{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T11:10:11Z","timestamp":1783941011848,"version":"3.55.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Otolaryngologic Clinics of North America"],"published-print":{"date-parts":[[2008,4]]},"DOI":"10.1016\/j.otc.2007.11.014","type":"journal-article","created":{"date-parts":[[2008,3,7]],"date-time":"2008-03-07T19:13:58Z","timestamp":1204917238000},"page":"347-358","source":"Crossref","is-referenced-by-count":17,"title":["Allergic Rhinitis\u2014Current Pharmacotherapy"],"prefix":"10.1016","volume":"41","author":[{"given":"John H.","family":"Krouse","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.otc.2007.11.014_bib1","unstructured":"Asthma and Allergy Foundation of America (AAFA). Consumer survey 2005. Available at: www.aafa.org\/display.cfm?id=7&sub=92&cont=529. Accessed September 30, 2007."},{"key":"10.1016\/j.otc.2007.11.014_bib2","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/S0194-5998(03)00257-2","article-title":"Allergic rhinitis: broader disease effects and implications for management","volume":"128","author":"Baroody","year":"2003","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.otc.2007.11.014_bib3","doi-asserted-by":"crossref","first-page":"929","DOI":"10.2165\/00019053-200422140-00003","article-title":"Cost-benefit analysis of first-generation antihistamines in the treatment of allergic rhinitis","volume":"22","author":"Sullivan","year":"2004","journal-title":"Pharmacoeconomics"},{"key":"10.1016\/j.otc.2007.11.014_bib4","first-page":"5","article-title":"Second generation H1-receptor antagonists","volume":"66","author":"Simons","year":"1991","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"Suppl 3","key":"10.1016\/j.otc.2007.11.014_bib5","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1046\/j.1365-2222.1999.0290s3212.x","article-title":"Cardiovascular safety of fexofenadine HCl","volume":"29","author":"Pratt","year":"1999","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.otc.2007.11.014_bib6","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2500\/108854100778249033","article-title":"Safety of second-generation antihistamines","volume":"21","author":"Philpot","year":"2000","journal-title":"Asthma Allergy Prox"},{"key":"10.1016\/j.otc.2007.11.014_bib7","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/j.1398-9995.2006.01277.x","article-title":"Efficacy of desloratadine in the treatment of allergic rhinitis: a meta-analysis of randomized, double-blind, controlled trials","volume":"62","author":"Canonica","year":"2007","journal-title":"Allergy"},{"key":"10.1016\/j.otc.2007.11.014_bib8","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.jaci.2004.05.070","article-title":"Levocetirizine improves quality of life and reduces costs in long-term management of persistent allergic rhinitis","volume":"114","author":"Bachert","year":"2004","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.otc.2007.11.014_bib9","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S1081-1206(10)60804-6","article-title":"Impact of azelastine nasal spray on symptoms and quality of life compared with cetirizine oral tablets in patients with seasonal allergic rhinitis","volume":"97","author":"Berger","year":"2006","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.otc.2007.11.014_bib10","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.clinthera.2005.04.012","article-title":"Effectiveness of azelastine nasal spray compared with oral cetirizine in patients with seasonal allergic rhinitis","volume":"27","author":"Corren","year":"2005","journal-title":"Clin Ther"},{"key":"10.1016\/j.otc.2007.11.014_bib11","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.1056\/NEJM200012213432501","article-title":"Phenylpropanolamine and the risk of hemorrhagic stroke","volume":"343","author":"Kernan","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.otc.2007.11.014_bib12","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1056\/NEJM198406213102502","article-title":"Peptide leukotriene release after antigen challenge in patients sensitive to ragweed","volume":"310","author":"Creticos","year":"1984","journal-title":"N Engl J Med"},{"key":"10.1016\/j.otc.2007.11.014_bib13","doi-asserted-by":"crossref","first-page":"887","DOI":"10.2165\/00003495-200767060-00005","article-title":"Montelukast in the treatment of allergic rhinitis: an evidence-based review","volume":"67","author":"Nayak","year":"2007","journal-title":"Drugs"},{"key":"10.1016\/j.otc.2007.11.014_bib14","doi-asserted-by":"crossref","first-page":"S147","DOI":"10.1067\/mai.2001.118891","article-title":"Allergic rhinitis and its impact on asthma","volume":"108","author":"Bousquet","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.otc.2007.11.014_bib15","series-title":"Rhinitis: mechanisms and management","article-title":"Intranasal corticosteroids","author":"Mygind","year":"1999"},{"key":"10.1016\/j.otc.2007.11.014_bib16","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S1081-1206(10)63030-X","article-title":"Comparison of once daily mometasone furoate (Nasonex) and fluticasone propionate aqueous nasal sprays for the treatment of perennial rhinitis","volume":"79","author":"Mandl","year":"1997","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.otc.2007.11.014_bib17","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/S1081-1206(10)62085-6","article-title":"Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis","volume":"89","author":"Yanez","year":"2002","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.otc.2007.11.014_bib18","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/BF03256639","article-title":"Comparison of intranasal corticosteroids and antihistamines in allergic rhinitis: a review of randomized, controlled trials","volume":"2","author":"Nielsen","year":"2003","journal-title":"Am J Respir Med"},{"key":"10.1016\/j.otc.2007.11.014_bib19","doi-asserted-by":"crossref","first-page":"E23","DOI":"10.1542\/peds.105.2.e23","article-title":"Detection of growth suppression in children during treatment with beclomethasone dipropionate","volume":"105","author":"Skoner","year":"2000","journal-title":"Pediatrics"},{"key":"10.1016\/j.otc.2007.11.014_bib20","doi-asserted-by":"crossref","first-page":"E22","DOI":"10.1542\/peds.105.2.e22","article-title":"Absence of growth retardation in children with perennial allergic rhinitis after one year of treatment with mometasone furoate aqueous nasal spray","volume":"105","author":"Schenkel","year":"2000","journal-title":"Pediatrics"},{"key":"10.1016\/j.otc.2007.11.014_bib21","first-page":"407","article-title":"No growth suppression in children treated with the maximum recommended dose of fluticasone propionate aqueous nasal spray for one year","volume":"23","author":"Allen","year":"2002","journal-title":"Allergy Asthma Proc"},{"key":"10.1016\/j.otc.2007.11.014_bib22","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s11882-005-0044-6","article-title":"Therapeutic approaches to mucus hypersecretion","volume":"5","author":"Yuta","year":"2005","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.otc.2007.11.014_bib23","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1177\/01945998901030S508","article-title":"Adjuncts to medical management of sinusitis","volume":"103","author":"Druce","year":"1990","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.otc.2007.11.014_bib24","first-page":"S29","article-title":"Treatment of allergic rhinitis and other immunoglobulin E-mediated diseases with anti-immunoglobulin E antibody","volume":"27","author":"Berger","year":"2006","journal-title":"Allergy Asthma Proc"}],"container-title":["Otolaryngologic Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0030666507002198?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0030666507002198?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,31]],"date-time":"2018-12-31T06:21:08Z","timestamp":1546237268000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0030666507002198"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["S0030666507002198"],"URL":"https:\/\/doi.org\/10.1016\/j.otc.2007.11.014","relation":{},"ISSN":["0030-6665"],"issn-type":[{"value":"0030-6665","type":"print"}],"subject":[],"published":{"date-parts":[[2008,4]]}}}