{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T15:56:21Z","timestamp":1789833381244,"version":"4.0.1"},"reference-count":37,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["oto.theclinics.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","theclinics.com","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngologic Clinics of North America"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1016\/j.otc.2015.04.002","type":"journal-article","created":{"date-parts":[[2015,6,23]],"date-time":"2015-06-23T05:05:29Z","timestamp":1435035929000},"page":"533-545","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":38,"title":["Functional Anatomy and Oncologic Barriers of the Larynx"],"prefix":"10.1016","volume":"48","author":[{"given":"Niv","family":"Mor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Blitzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.otc.2015.04.002_bib1","series-title":"Neurologic disorders of the larynx","first-page":"3","article-title":"Anatomy of the larynx","author":"Cooper","year":"2009"},{"issue":"3","key":"10.1016\/j.otc.2015.04.002_bib2","first-page":"252","article-title":"Posterior commissure of the human larynx revisited","volume":"24","author":"Tucker","year":"2010","journal-title":"J\u00a0Voice"},{"key":"10.1016\/j.otc.2015.04.002_bib3","first-page":"173","article-title":"The periepiglottic space: topographic relations and histological organization","volume":"188","author":"Reidenbach","year":"1996","journal-title":"J\u00a0Anat"},{"issue":"7","key":"10.1016\/j.otc.2015.04.002_bib4","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1288\/00005537-199407000-00019","article-title":"The innervation of the human posterior cricoarytenoid muscle: evidence for at least two neuromuscular compartments","volume":"104","author":"Sanders","year":"1994","journal-title":"Laryngoscope"},{"key":"10.1016\/j.otc.2015.04.002_bib5","series-title":"Dynamic aspects of speech production","first-page":"13","article-title":"Structure and vibratory behavior of the vocal folds","author":"Hirano","year":"1977"},{"key":"10.1016\/j.otc.2015.04.002_bib6","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1002\/ca.22015","article-title":"The laryngeal saccule: clinical significance","volume":"25","author":"Porter","year":"2012","journal-title":"Clin Anat"},{"key":"10.1016\/j.otc.2015.04.002_bib7","first-page":"46","article-title":"Anatomische Untesuchungen uber das Larynxodem","volume":"42","author":"Hajek","year":"1891","journal-title":"Arch Klin Chir"},{"issue":"11","key":"10.1016\/j.otc.2015.04.002_bib8","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1288\/00005537-198211000-00001","article-title":"Regional behavioral variations of epidermoid carcinoma of the head and neck: a study in an animal model","volume":"92","author":"Blitzer","year":"1982","journal-title":"Laryngoscope"},{"key":"10.1016\/j.otc.2015.04.002_bib9","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1177\/000348945606500409","article-title":"Further studies upon the submucosal compartments and lymphatics of the larynx by injection of dyes and radioisotopes","volume":"65","author":"Pressman","year":"1956","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"10.1016\/j.otc.2015.04.002_bib10","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S0030-6665(20)30488-6","article-title":"Anatomy of the larynx, trachea, and bronchi","volume":"28","author":"Armstrong","year":"1995","journal-title":"Otolaryngol Clin North Am"},{"key":"10.1016\/j.otc.2015.04.002_bib11","first-page":"156","article-title":"The development of the larynx","volume":"44","author":"Frazer","year":"1909","journal-title":"J\u00a0Anat Physiol"},{"key":"10.1016\/j.otc.2015.04.002_bib12","first-page":"308","article-title":"A\u00a0histological demonstration of the development of laryngeal connective tissue compartments","volume":"66","author":"Tucker","year":"1962","journal-title":"Trans Am Acad Ophthalmol Otolaryngol"},{"issue":"10","key":"10.1016\/j.otc.2015.04.002_bib13","doi-asserted-by":"crossref","first-page":"2648","DOI":"10.1002\/1097-0142(19940515)73:10<2648::AID-CNCR2820731029>3.0.CO;2-D","article-title":"New barriers to ventricular invasion in paraglottic laryngeal cancer","volume":"73","author":"Beitler","year":"1994","journal-title":"Cancer"},{"issue":"11","key":"10.1016\/j.otc.2015.04.002_bib14","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1177\/0003489414538398","article-title":"Hajek revisited: a histological examination of the quadrangular membrane","volume":"123","author":"Young","year":"2014","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"10.1016\/j.otc.2015.04.002_bib15","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1288\/00005537-199208000-00008","article-title":"Neoplastic infiltration of laryngeal cartilages: histocytochemical study","volume":"102","author":"Gallo","year":"1992","journal-title":"Laryngoscope"},{"key":"10.1016\/j.otc.2015.04.002_bib16","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1084\/jem.141.2.427","article-title":"Inhibition of tumor angiogenesis mediated by cartilage","volume":"141","author":"Brem","year":"1975","journal-title":"J\u00a0Exp Med"},{"issue":"2A","key":"10.1016\/j.otc.2015.04.002_bib17","first-page":"311","article-title":"A\u00a0clonal human chondrosarcoma cell line produces an anti-angiogenic antitumor factor","volume":"10","author":"Takigawa","year":"1990","journal-title":"Anticancer Res"},{"issue":"7","key":"10.1016\/j.otc.2015.04.002_bib18","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/0309-1651(85)90054-2","article-title":"Cartilage-derived anti-tumor factor (CATF) inhibits the proliferation of endothelial cells in culture","volume":"9","author":"Takigawa","year":"1985","journal-title":"Cell Biol Int Rep"},{"issue":"2","key":"10.1016\/j.otc.2015.04.002_bib19","first-page":"357","article-title":"A\u00a0factor in conditioned medium of rabbit costal chondrocytes inhibits the proliferation of cultured endothelial cells and angiogenesis induced by B16 melanoma: its relation with cartilage-derived anti-tumor factor (CATF)","volume":"14","author":"Takigawa","year":"1987","journal-title":"Biochem Int"},{"issue":"1","key":"10.1016\/j.otc.2015.04.002_bib20","first-page":"65","article-title":"Regulation of tumor invasion by cartilage derived anti-invasion factor in\u00a0vitro","volume":"67","author":"Pauli","year":"1981","journal-title":"J\u00a0Natl Cancer Inst"},{"issue":"1","key":"10.1016\/j.otc.2015.04.002_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/bbrc.1999.0610","article-title":"Cartilage-derived growth factor and antitumor factor: past, present, and future studies","volume":"259","author":"Suzuki","year":"1999","journal-title":"Biochem Biophys Res Commun"},{"issue":"4","key":"10.1016\/j.otc.2015.04.002_bib22","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1288\/00005537-198204000-00015","article-title":"Anatomical routes for cancer invasion of laryngeal cartilages","volume":"92","author":"Yeager","year":"1982","journal-title":"Laryngoscope"},{"key":"10.1016\/j.otc.2015.04.002_bib23","first-page":"342","article-title":"The anterior commissure tendon","volume":"52","author":"Broyles","year":"1943","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"3","key":"10.1016\/j.otc.2015.04.002_bib24","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1288\/00005537-198303000-00020","article-title":"Behavior of cancer at the anterior commissure of the larynx","volume":"93","author":"Bagatella","year":"1983","journal-title":"Laryngoscope"},{"issue":"Suppl.1","key":"10.1016\/j.otc.2015.04.002_bib25","first-page":"S 117","article-title":"Staging of laryngeal cancer: endoscopy, computed tomography and magnetic resonance versus histopathology","volume":"254","author":"Zbfiren","year":"1997","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"3","key":"10.1016\/j.otc.2015.04.002_bib26","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/S0720-048X(99)00144-8","article-title":"Neoplastic invasion of laryngeal cartilage: radiologic diagnosis and therapeutic implications","volume":"33","author":"Becker","year":"2000","journal-title":"Eur J Radiol"},{"issue":"3","key":"10.1016\/j.otc.2015.04.002_bib27","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1002\/hed.2890040304","article-title":"Framework invasion by laryngeal carcinomas","volume":"4","author":"Pittam","year":"1982","journal-title":"Head Neck Surg"},{"key":"10.1016\/j.otc.2015.04.002_bib28","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/0002-9610(89)90027-5","article-title":"Framework invasion by laryngeal carcinoma","volume":"154","author":"Gregor","year":"1987","journal-title":"Am J Surg"},{"key":"10.1016\/j.otc.2015.04.002_bib29","series-title":"Surgical pathology of the head and neck","first-page":"109","article-title":"Diseases of the larynx, hypopharynx, and trachea","author":"Barnes","year":"2009"},{"issue":"4","key":"10.1016\/j.otc.2015.04.002_bib30","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1177\/000348949610500412","article-title":"Carcinoma of the anterior commissure of the larynx: I embryological and anatomic","volume":"105","author":"Rucci","year":"1996","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"5","key":"10.1016\/j.otc.2015.04.002_bib31","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1177\/000348949610500512","article-title":"Carcinoma of the anterior commissure of the larynx: II proposal of a new staging","volume":"105","author":"Rucci","year":"1996","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"10.1016\/j.otc.2015.04.002_bib32","first-page":"41","article-title":"Effects of ageing on the insertion zones of the human vocal fold","volume":"196","author":"Paulsen","year":"2000","journal-title":"J\u00a0Anat"},{"key":"10.1016\/j.otc.2015.04.002_bib33","first-page":"637","article-title":"Anterior commissure cancer- a clinical and laboratory study of 39 cases","volume":"4","author":"Kirchner","year":"1975","journal-title":"Can J Otolaryngol"},{"key":"10.1016\/j.otc.2015.04.002_bib34","doi-asserted-by":"crossref","first-page":"392","DOI":"10.3109\/00016488409132910","article-title":"Invasion of the framework by laryngeal cancer","volume":"97","author":"Kirchner","year":"1984","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.otc.2015.04.002_bib35","first-page":"503","article-title":"Intralaryngeal barriers to the spread of cancer","volume":"103","author":"Kirchner","year":"1987","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.otc.2015.04.002_bib36","first-page":"1","article-title":"Functional organ preservation in laryngeal and hypopharyngeal cancer","volume":"10","author":"Ambrosch","year":"2011","journal-title":"GMS Curr Top Otorhinolaryngol Head Neck Surg"},{"key":"10.1016\/j.otc.2015.04.002_bib37","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/bjc.1980.31","article-title":"Prostaglandin-like material extracted from squamous cell carcinomas of the head and neck","volume":"41","author":"Bennett","year":"1980","journal-title":"Br J Cancer"}],"container-title":["Otolaryngologic Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0030666515000481?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0030666515000481?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,4]],"date-time":"2020-09-04T00:40:55Z","timestamp":1599180055000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0030666515000481"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":37,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["S0030666515000481"],"URL":"https:\/\/doi.org\/10.1016\/j.otc.2015.04.002","relation":{},"ISSN":["0030-6665"],"issn-type":[{"value":"0030-6665","type":"print"}],"subject":[],"published":{"date-parts":[[2015,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Functional Anatomy and Oncologic Barriers of the Larynx","name":"articletitle","label":"Article Title"},{"value":"Otolaryngologic Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.otc.2015.04.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}