{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T04:01:29Z","timestamp":1782878489217,"version":"3.54.5"},"reference-count":38,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","theclinics.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngologic Clinics of North America"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.otc.2024.12.002","type":"journal-article","created":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T08:35:20Z","timestamp":1737707720000},"page":"475-483","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Dysphonia and Laryngopharyngeal Reflux"],"prefix":"10.1016","volume":"58","author":[{"given":"H. Steven","family":"Sims","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Blumenstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.otc.2024.12.002_bib1","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1136\/gut.2004.051821","article-title":"Epidemiology of gastro-oesophageal reflux disease: a systematic review","volume":"54","author":"Dent","year":"2005","journal-title":"Gut"},{"issue":"3","key":"10.1016\/j.otc.2024.12.002_bib2","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.bpg.2013.06.008","article-title":"Epidemiology of reflux symptoms and GORD","volume":"27","author":"Ronkainen","year":"2013","journal-title":"Best Pract Res Clin Gastroenterol"},{"issue":"4","key":"10.1016\/j.otc.2024.12.002_bib3","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/1753-6405.12623","article-title":"Culture and healthy lifestyles: a qualitative exploration of the role of food and physical activity in three urban Australian Indigenous communities","volume":"41","author":"Crowe","year":"2017","journal-title":"Aust N Z J Public Health"},{"key":"10.1016\/j.otc.2024.12.002_bib4","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1136\/jech-2023-220311","article-title":"Causal links between socioeconomic status, leisure sedentary behaviors and gastro-oesophageal reflux disease: a multivariable two-sample Mendelian randomisation study","volume":"77","author":"Lian","year":"2023","journal-title":"J Epidemiol Community Health"},{"issue":"3","key":"10.1016\/j.otc.2024.12.002_bib5","doi-asserted-by":"crossref","first-page":"194","DOI":"10.24871\/1732016194-199","article-title":"Inducing and aggravating factors of gastroesophageal reflux symptoms","volume":"17","author":"Mardhiyah","year":"2017","journal-title":"The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy"},{"issue":"1","key":"10.1016\/j.otc.2024.12.002_bib6","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1002\/lio2.715","article-title":"Analysis of socioeconomic factors in laryngology clinic utilization for treatment of dysphonia","volume":"7","author":"White","year":"2021","journal-title":"Laryngoscope Investig Otolaryngol"},{"issue":"11","key":"10.1016\/j.otc.2024.12.002_bib7","first-page":"e6103","article-title":"Depression and anxiety in patients with gastroesophageal reflux disorder with and without chest pain","volume":"11","author":"Mohammad","year":"2019","journal-title":"Cureus"},{"issue":"5","key":"10.1016\/j.otc.2024.12.002_bib8","first-page":"457","article-title":"Depression promotes gastroesophageal reflux disease: new evidence based on mendelian randomization","volume":"34","author":"Chen","year":"2023","journal-title":"Turk J Gastroenterol"},{"issue":"8","key":"10.1016\/j.otc.2024.12.002_bib9","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1002\/lary.25819","article-title":"Voice problems and depression among adults in the United States","volume":"126","author":"Marmor","year":"2016","journal-title":"Laryngoscope"},{"issue":"1","key":"10.1016\/j.otc.2024.12.002_bib10","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1038\/s41467-023-36223-7","article-title":"Long-term gastrointestinal outcomes of COVID-19","volume":"14","author":"Xu","year":"2023","journal-title":"Nat Commun"},{"issue":"6","key":"10.1016\/j.otc.2024.12.002_bib11","doi-asserted-by":"crossref","first-page":"971.e17","DOI":"10.1016\/j.jvoice.2021.07.001","article-title":"Persistent dysphonia in hospitalized COVID-19 patients","volume":"37","author":"Leis-Cofi\u00f1o","year":"2023","journal-title":"J Voice"},{"issue":"11","key":"10.1016\/j.otc.2024.12.002_bib12","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1002\/jmv.26080","article-title":"The association between laryngopharyngeal reflux and COVID-19 is still not demonstrated","volume":"92","author":"Lechien","year":"2020","journal-title":"J Med Virol"},{"key":"10.1016\/j.otc.2024.12.002_bib13","doi-asserted-by":"crossref","first-page":"95S","DOI":"10.1177\/01455613221075222","article-title":"The first case report of bilateral vagal neuropathy presenting with dysphonia following COVID-19 infection","volume":"103","author":"An","year":"2022","journal-title":"Ear Nose Throat J"},{"issue":"4","key":"10.1016\/j.otc.2024.12.002_bib14","first-page":"e57617","article-title":"COVID-19 and its sequelae masquerading as gastrointestinal ailments: a report of gastroesophageal reflux disease (GERD) and review of recent cases","volume":"16","author":"Shweikeh","year":"2024","journal-title":"Cureus"},{"issue":"11","key":"10.1016\/j.otc.2024.12.002_bib15","doi-asserted-by":"crossref","first-page":"2631","DOI":"10.1002\/lary.28506","article-title":"The reflux symptom index and symptom overlap in dysphonic patients","volume":"130","author":"Kavookjian","year":"2020","journal-title":"Laryngoscope"},{"issue":"4","key":"10.1016\/j.otc.2024.12.002_bib16","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1007\/s11605-022-05574-9","article-title":"Voice hoarseness with reflux as a suspected etiology: incidence, evaluation, treatment, and symptom outcomes","volume":"27","author":"Korsunsky","year":"2023","journal-title":"J Gastrointest Surg"},{"issue":"1","key":"10.1016\/j.otc.2024.12.002_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4103\/jlv.JLV_6_19","article-title":"A study of relationship between reflux symptom index and reflux finding score in patients with laryngopharyngeal reflux","volume":"9","author":"Nilakhe","year":"2019","journal-title":"J Laryngol Voice"},{"issue":"5","key":"10.1016\/j.otc.2024.12.002_bib18","doi-asserted-by":"crossref","first-page":"C1038","DOI":"10.1152\/ajpcell.00266.2006","article-title":"Gastric type H+, K+-ATPase in the cochlear lateral wall is critically involved in formation of the endocochlear potential","volume":"291","author":"Shibata","year":"2006","journal-title":"Am J Physiol Cell Physiol"},{"issue":"1","key":"10.1016\/j.otc.2024.12.002_bib19","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/AUD.0000000000000347","article-title":"Prospective study of gastroesophageal reflux, use of proton pump inhibitors and H2-receptor antagonists, and risk of hearing loss","volume":"38","author":"Lin","year":"2017","journal-title":"Ear Hear"},{"key":"10.1016\/j.otc.2024.12.002_bib20","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1097\/00005537-200108000-00001","article-title":"The validity and reliability of the reflux finding score (RFS)","volume":"111","author":"Belafsky","year":"2001","journal-title":"Laryngoscope"},{"issue":"1","key":"10.1016\/j.otc.2024.12.002_bib21","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/nyas.14728","article-title":"An update on current treatment strategies for laryngopharyngeal reflux symptoms","volume":"1510","author":"Krause","year":"2022","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.otc.2024.12.002_bib22","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.14309\/ajg.0000000000000734","article-title":"ACG clin-ical guidelines: clinical use of esophageal physiologic testing","volume":"115","author":"Gyawali","year":"2020","journal-title":"Am J Gastroenterol"},{"issue":"9","key":"10.1016\/j.otc.2024.12.002_bib23","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1111\/j.1572-0241.2004.30273.x","article-title":"The influence of rapid food intake on postprandial reflux: studies in healthy volunteers","volume":"99","author":"Wildi","year":"2004","journal-title":"Am J Gastroenterol"},{"issue":"5","key":"10.1016\/j.otc.2024.12.002_bib24","doi-asserted-by":"crossref","first-page":"379","DOI":"10.4318\/tjg.2013.0568","article-title":"The effect of the speed of eating on acid reflux and symptoms of patients with gastroesophageal reflux disease","volume":"24","author":"Valitova","year":"2013","journal-title":"Turk J Gastroenterol"},{"issue":"5","key":"10.1016\/j.otc.2024.12.002_bib25","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1002\/lary.27591","article-title":"Clinical outcomes of laryngopharyngeal reflux treatment: a systematic review and meta-analysis","volume":"129","author":"Lechien","year":"2019","journal-title":"Laryngoscope"},{"issue":"21","key":"10.1016\/j.otc.2024.12.002_bib26","first-page":"00563","article-title":"Distinct clinical physiologic phenotypes of patients with laryngeal symptoms referred for reflux evaluation","volume":"S1542-3565","author":"Yadlapati","year":"2021","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.otc.2024.12.002_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.mehy.2020.110460","article-title":"Laryngopharyngeal reflux: the microbiota theory","volume":"146","author":"Lechien","year":"2021","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.otc.2024.12.002_bib28","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.clnesp.2022.09.015","article-title":"What is the efficacy of dietary, nutraceutical, and probiotic interventions for the management of gastroesophageal reflux disease symptoms? A systematic literature review and meta-analysis","volume":"52","author":"Martin","year":"2022","journal-title":"Clinical Nutrition ESPEN"},{"key":"10.1016\/j.otc.2024.12.002_bib29","series-title":"Laryngopharyngeal reflux disease: integrative approaches","year":"2019"},{"issue":"2","key":"10.1016\/j.otc.2024.12.002_bib30","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1159\/000479000","article-title":"The ameliorating effect of Lactobacillus gasseri OLL2716 on functional dyspepsia in Helicobacter pylori-uninfected individuals: a randomized controlled study","volume":"96","author":"Ohtsu","year":"2017","journal-title":"Digestion"},{"key":"10.1016\/j.otc.2024.12.002_bib31","article-title":"The effect of ginger (Zingiber officinalis) and artichoke (Cynara cardunculus) extract supplementation on functional dyspepsia: a randomised, double-blind, and placebo-controlled clinical trial","volume":"1","author":"Giacosa","year":"2015","journal-title":"Evid base Compl Alternative Med"},{"issue":"7","key":"10.1016\/j.otc.2024.12.002_bib32","doi-asserted-by":"crossref","first-page":"3756.e68","DOI":"10.1002\/ptr.7074","article-title":"A standardized extract of Opuntia ficus-indica (L.) Mill and Olea europaea L. improves gastrointestinal discomfort: a double-blinded randomizedcontrolled study","volume":"35","author":"Malfa","year":"2021","journal-title":"Phytother Res"},{"issue":"21","key":"10.1016\/j.otc.2024.12.002_bib33","doi-asserted-by":"crossref","first-page":"2291.e9","DOI":"10.3748\/wjg.v24.i21.2291","article-title":"Fiber-enriched diet helps to control symptoms and improves esophageal motility in patients with non-erosive gastroesophageal reflux disease","volume":"24","author":"Morozov","year":"2018","journal-title":"World J Gastroenterol"},{"issue":"6","key":"10.1016\/j.otc.2024.12.002_bib34","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.3390\/nu13061956","article-title":"Colostrum therapy for human gastrointestinal health and disease","volume":"13","author":"Chandwe","year":"2021","journal-title":"Nutrients"},{"issue":"6","key":"10.1016\/j.otc.2024.12.002_bib35","doi-asserted-by":"crossref","first-page":"724","DOI":"10.2174\/1389557520666201127104907","article-title":"Fenugreek cultivation with emphasis on historical aspects and its uses in traditional medicine and modern pharmaceutical science","volume":"21","author":"Sun","year":"2021","journal-title":"Mini Rev Med Chem"},{"issue":"7","key":"10.1016\/j.otc.2024.12.002_bib36","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1001\/jamaoto.2019.0315","article-title":"Surgical treatment for laryngopharyngeal reflux disease: a systematic review","volume":"145","author":"Lechien","year":"2019","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"issue":"3","key":"10.1016\/j.otc.2024.12.002_bib37","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1159\/000444147","article-title":"Effect of vagus nerve injury on the outcome of antireflux surgery: an extensive literature review","volume":"33","author":"van Rijn","year":"2016","journal-title":"Dig Surg"},{"issue":"10","key":"10.1016\/j.otc.2024.12.002_bib38","doi-asserted-by":"crossref","first-page":"2566","DOI":"10.1007\/s00268-017-4058-8","article-title":"Surgical treatment of extraesophageal manifestations of gastroesophageal reflux disease","volume":"41","author":"Sidwa","year":"2017","journal-title":"World J Surg"}],"container-title":["Otolaryngologic Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0030666524001981?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0030666524001981?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T04:22:22Z","timestamp":1746764542000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0030666524001981"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["S0030666524001981"],"URL":"https:\/\/doi.org\/10.1016\/j.otc.2024.12.002","relation":{},"ISSN":["0030-6665"],"issn-type":[{"value":"0030-6665","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dysphonia and Laryngopharyngeal Reflux","name":"articletitle","label":"Article Title"},{"value":"Otolaryngologic Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.otc.2024.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}