{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:40:21Z","timestamp":1760971221824,"version":"build-2065373602"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":4399,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2004,5]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>At present, endonasal paraseptal splints are devices frequently employed in rhinosurgery. We evaluated the local tolerance of a newly shaped device, the Guastella\/Mantovani splint (G\/M\u2010SVS), with respect to the physiological mechanism of mucociliary clearance.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND SETTING<\/jats:title><jats:p>The study involved 20 patients who underwent septoplasty and\/or turbinoplasty or other nasal surgical procedures. A sample of ciliated cells was obtained by nasal brushing and was examined ex vivo to determine the ciliary beat frequency (CBF) and morphology, before and 15\u00a0days after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Before surgery the mean CBF was 10.87\u00a0Hz \u00b1 0.56\u00a0Hz and when splints were removed it was 10.25\u00a0Hz \u00b1 1.9\u00a0Hz. Morphological evaluation of the ciliary motion after surgery demonstrated a normal, coordinated beat.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>The G\/M\u2010SVS does not appear to interfere with the physiological mechanism of mucociliary clearance since CBF remain within a normal range.<\/jats:p><\/jats:sec><jats:sec><jats:title>SIGNIFICANCE<\/jats:title><jats:p>This is the first study that demonstrates an optimal tolerability and safety of the septo\u2010valvular splints on nasal mucosa. (Otolaryngol Head Neck Surg 2004;130:558\u201062.)<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2003.07.013","type":"journal-article","created":{"date-parts":[[2004,5,13]],"date-time":"2004-05-13T09:27:24Z","timestamp":1084440444000},"page":"558-562","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Nasal Ciliary Beat After Insertion of Septo\u2010Valvular Splints"],"prefix":"10.1002","volume":"130","author":[{"suffix":"MD, PHD","given":"G.","family":"Piatti","sequence":"first","affiliation":[{"name":"Institute of Respiratory Diseases Ospedale Maggiore di Milano, IRCCS University of Milan Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"MD","given":"A.","family":"Scotti","sequence":"additional","affiliation":[{"name":"Department of Otolaringology Ospedale Maggiore di Milano, IRCCS University of Milan Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"MD","given":"U.","family":"Ambrosetti","sequence":"additional","affiliation":[{"name":"Department of Otolaringology Ospedale Maggiore di Milano, IRCCS University of Milan Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,17]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-997334"},{"key":"e_1_2_5_3_1","first-page":"220","volume-title":"Cilia, mucus and mucociliary interactions.","author":"Mladina R","year":"1988"},{"issue":"3","key":"e_1_2_5_4_1","first-page":"197","article-title":"The postoperative nasal dressing: a new intranasal splint.","volume":"28","author":"Bernal\u2010Sprekelsen M","year":"1990","journal-title":"Rhinology"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100103391"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199704000-00020"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1992.tb00982.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200008000-00039"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199404001-00004"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1955.03830020055011"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-197509000-00008"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199405000-00010"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988108900123"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1986.03780030093019"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459989511300519"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198606000-00003"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.48.10.1018"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1955.00720020435007"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198505000-00005"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199211000-00015"},{"key":"e_1_2_5_21_1","first-page":"613","volume-title":"Rhinoplasty.","author":"Kern EB","year":"1993"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2003.07.013","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.otohns.2003.07.013","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2003.07.013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:58:50Z","timestamp":1760968730000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2003.07.013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,5]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2004,5]]}},"alternative-id":["10.1016\/j.otohns.2003.07.013"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2003.07.013","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[2004,5]]},"assertion":[{"value":"2016-05-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}