{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T11:11:00Z","timestamp":1760958660612,"version":"build-2065373602"},"reference-count":35,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":4460,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2004,3]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Topical nasal steroids such as beclomethasone dipropionate and fluticasone propionate have been widely used in the treatment of rhinitis and polyposis. An increase in infection has occurred with the use of fluticasone propionate after endoscopic polypectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>The purpose of this study was to determine the prevalence of nasal and paranasal infections with the use of topic nasal steroids after endoscopic polypectomy and to compare the recurrence rates of the polyposis.<\/jats:p><\/jats:sec><jats:sec><jats:title>DESIGN AND SETTING<\/jats:title><jats:p>We conducted a prospective, comparative, open, experimental, longitudinal study at an academic tertiary referral medical center.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>One hundred sixty\u2010two patients in whom endoscopic polypectomy had been indicated were randomly divided into 3\u00a0groups of 54 patients each. The patients from the first group were treated with saline lavage only. Patients from the second group also received fluticasone propionate 400 \u03bcg\/day in nasal spray after lavage. Patients from the third group received beclomethasone dipropionate 600 \u03bcg\/day after lavage. The prevalence of infections and recurrence of polyposis was compared in the 3\u00a0groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Three patients, 2\u00a0in the placebo group and 1\u00a0in the beclomethasone group, developed infections during the first 3\u00a0months after surgical procedure. The recurrence of polyps in the group without steroids was 44%. In contrast, 15% from the patients treated with fluticasone showed recurrence of polyposis; furthermore, 26% of the patients treated with beclomethasone showed recurrence of polypsosis, with a minimum follow\u2010up of 12\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>The use of nasal steroids does not seem to increase the prevalence of infections after endoscopic polypectomy. (Otolaryngol Head Neck Surg 2004;130:319\u201322.)<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2003.09.021","type":"journal-article","created":{"date-parts":[[2004,4,9]],"date-time":"2004-04-09T05:21:57Z","timestamp":1081488117000},"page":"319-322","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Infections after Endoscopic Polypectomy Using Nasal Steroids"],"prefix":"10.1002","volume":"130","author":[{"given":"Daniel","family":"Bross\u2010Soriano","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u201cManuel Gea Gonzalez\u201d General Hospital Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose R.","family":"Arrieta\u2010G\u00f3mez","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u201cManuel Gea Gonzalez\u201d General Hospital Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9ctor","family":"Prado\u2010Calleros","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u201cManuel Gea Gonzalez\u201d General Hospital Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,17]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"123","article-title":"Endoscopy of the nose","volume":"104","author":"Messerklinger W.","year":"1978","journal-title":"Arch Otolaryngol"},{"volume-title":"Functional endoscopic sinus surgery","year":"1991","author":"Stammberger H.","key":"e_1_2_6_3_1"},{"key":"e_1_2_6_4_1","first-page":"5","article-title":"Cirug\u00eda endosc\u00f3pica de senos paranasales","volume":"16","author":"Friedman M.","year":"1989","journal-title":"Clin Otorrinolaringol Norte Am"},{"key":"e_1_2_6_5_1","first-page":"1861","volume-title":"Otolaryngology Head Neck Surgery","author":"Kennedy DW","year":"1993"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198901000-00001"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459989110500514"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198303000-00006"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198812000-00004"},{"key":"e_1_2_6_10_1","first-page":"179","volume-title":"Surgery of the paranasal sinuses","author":"Blitzer A.","year":"1985"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)31895-8"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)31893-4"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1991.01870130025006"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988910100107"},{"key":"e_1_2_6_15_1","first-page":"35","article-title":"The physiology of drainage of nasal mucus","volume":"53","author":"Hilding AC","year":"1984","journal-title":"Ann Otolaryngol"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1985.00800120037003"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988609400202"},{"key":"e_1_2_6_18_1","first-page":"82","article-title":"Prognosis factors, outcome and staging in ethmoid sinus surgery","volume":"102","author":"Kennedy DW","year":"1992","journal-title":"Laryngoscope"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1985.00800110054002"},{"key":"e_1_2_6_20_1","first-page":"6","article-title":"Complications of endoscopic sinus surgery","volume":"118","author":"Blemming M.","year":"1992","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198907000-00004"},{"key":"e_1_2_6_22_1","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1288\/00005537-198903000-00008","article-title":"Fatal and major complications secondary to nasal and sinus surgery","volume":"99","author":"Maniglia AJ","year":"1989","journal-title":"Laryngoscope"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1996.01890190025007"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100089957"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1994.00420230086010"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.1996.tb00103.x"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1994.tb03320.x"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.50.10.1044"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.104.5.1352"},{"volume-title":"Primer for biostatistics","year":"1992","author":"Glantz SA","key":"e_1_2_6_30_1"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348948909801112"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1985.00800120037003"},{"volume-title":"Endoscopy of the paranasal sinuses","year":"1983","author":"Stammberger H","key":"e_1_2_6_33_1"},{"key":"e_1_2_6_34_1","first-page":"125","article-title":"Endoscopic surgery of the nose and the paranasal sinuses","volume":"65","author":"Kennedy DW","year":"1986","journal-title":"Ear Nose Throat J"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199409000-00006"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198304000-00019"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2003.09.021","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.otohns.2003.09.021","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2003.09.021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:47:44Z","timestamp":1760957264000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2003.09.021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["10.1016\/j.otohns.2003.09.021"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2003.09.021","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[2004,3]]},"assertion":[{"value":"2016-05-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}