{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T10:11:28Z","timestamp":1792059088874,"version":"4.4.0"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":4003,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2005,6]]},"abstract":"<jats:sec><jats:title>BACKGROUND AND OBJECTIVE<\/jats:title><jats:p>Patients who require surgery for chronic otitis media with perforation and cholesteatoma frequently provide no residual tympanic membrane that is usable in grafting procedures. A novel technique of total tympanic membrane reconstruction (TTMR) is described that maximizes perforation closure rate in these situations while minimizing mucosalization, incomplete healing, and anterior blunting. The specific aim of this report is to assess the safety and efficacy of TTMR and to compare the results obtained with AlloDerm compared with temporalis fascia as a grafting material.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>The records of 50 patients operated within the years 1999 and the 2004 were reviewed. TTMR with intact canal wall was performed in all cases. Both clinical and audiometric data were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Overall perforation closure rate was 92%. There was no statistical significance in closure rate when grafting with AlloDerm versus temporalis fascia. A statistically significant shortened healing time was observed with AlloDerm grafting.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>TTMR is a highly effective and safe technique.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2004.12.013","type":"journal-article","created":{"date-parts":[[2005,6,10]],"date-time":"2005-06-10T11:47:16Z","timestamp":1118404036000},"page":"906-915","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Total tympanic membrane reconstruction: AlloDerm versus temporalis fascia"],"prefix":"10.1002","volume":"132","author":[{"given":"Andrew J.","family":"Fishman","sequence":"first","affiliation":[{"name":"Department of Otolaryngology New York University School of Medicine New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle S.","family":"Marrinan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology New York University School of Medicine New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina C.","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology New York University School of Medicine New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seth J.","family":"Kanowitz","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology New York University School of Medicine New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199712001-00001"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199712001-00002"},{"key":"e_1_2_7_4_1","first-page":"15","article-title":"Annular wedge tympanoplasty: a variation of overlay myringoplasty","volume":"17","author":"Albera R","year":"1997","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"e_1_2_7_5_1","first-page":"15","article-title":"Overlay versus underlay tympanoplasty. 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