{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T07:44:17Z","timestamp":1778139857174,"version":"3.51.4"},"reference-count":9,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":4034,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2005,5]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>To histologically evaluate the long\u2010term outcomes of autologous fat grafts after injection laryngoplasty in the human larynx.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND SETTING<\/jats:title><jats:p>We injected liposuctioned fat for vocal fold augmentation in patients with vocal fold paralysis. We suctioned autologous fat from the low abdomen with an 18\u2010G disposable needle and a 20\u2010mL disposable syringe under negative pressure. This is different from the conventional liposuction technique and avoids the use of special equipment. In this article, we report the histological evaluation of 2 patients (patient 1: 12\u00a0months, patient 2: 41\u00a0months) who required total laryngectomy after autologous fat injection into the vocal folds.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Histological examination revealed normal\u2010appearing viable adipocytes with minimal inflammatory response in both patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>Our liposuctioned autologous fat injection histologically offered long\u2010term improvement in patients with impaired glottal closure from vocal fold paralysis. (Otolaryngol Head Neck Surg 2005;132:685\u2010688.)<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2005.01.005","type":"journal-article","created":{"date-parts":[[2005,5,11]],"date-time":"2005-05-11T07:51:09Z","timestamp":1115797869000},"page":"685-688","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Long\u2010term histological outcomes of injected autologous fat into human vocal folds after secondary laryngectomy"],"prefix":"10.1002","volume":"132","author":[{"given":"Hisanori","family":"Sasai","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery Osaka General Medical Center Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Tokyo Senbai Hospital Tokyo 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