{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:49:53Z","timestamp":1792633793027,"version":"4.5.0"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":4034,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2005,5]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>Acute epiglottitis is a potentially disastrous disease seen occasionally in otolaryngology emergency service. This study reports our experiences in managing adult patients with acute epiglottitis in a Taiwanese setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN<\/jats:title><jats:p>Admission medical records from 46 adult patients with acute epiglottitis over a period of 8 years in a tertiary referral otolaryngology service were retrospectively reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>No mortality was reported; 4 (8.7%) patients were supported by artificial airway. A total of 16 (34.8%) patients had comorbid conditions; hypertension and diabetes mellitus were the most common systemic diseases. Patients who needed artificial airway support tended to have more systemic comorbidities (<jats:italic>P<\/jats:italic> = 0.001) and a higher level of hyperglycemia (<jats:italic>P<\/jats:italic> = 0.004) than those who did not need airway support. The incidences of drooling, stridor\/dyspnea, and muffled voice were significantly higher in the airway\u2010supported group (<jats:italic>P<\/jats:italic> &lt; 0.05). Stridor\/dyspnea is a reliable clinical predictor of airway compromise (odds ratio 2.94; <jats:italic>P<\/jats:italic> = 0.0277).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Dyspnea is a warning sign of impending airway collapse during an episode of acute epiglottitis. Adult patients with more systemic comorbidities might bear higher risk of airway compromise; the role of diabetes mellitus can't be overlooked. (Otolaryngol Head Neck Surg 2005;132:689\u2010693.)<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2005.01.011","type":"journal-article","created":{"date-parts":[[2005,5,11]],"date-time":"2005-05-11T07:51:09Z","timestamp":1115797869000},"page":"689-693","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Adult acute epiglottitis: Experiences in a Taiwanese setting"],"prefix":"10.1002","volume":"132","author":[{"given":"Yen\u2010Liang","family":"Chang","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Cathay General Hospital Taipei Taiwan"},{"name":"Fu Jen Catholic University School of Medicine College of Public Health China Medical University Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih\u2010Hung","family":"Lo","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Cathay General Hospital Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pa\u2010Chun","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Cathay General Hospital Taipei Taiwan"},{"name":"Department of Public Health College of Public Health China Medical University Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Hsiang","family":"Shu","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology College of Public Health National Taiwan University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198605013141801"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199801000-00012"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198605013141809"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(83)80045-3"},{"key":"e_1_2_6_6_1","first-page":"31","article-title":"Epiglottic abscess: its occurrence and management","volume":"6","author":"Heeneman H","year":"1977","journal-title":"J Otolaryngol"},{"key":"e_1_2_6_7_1","first-page":"332","article-title":"Adult epiglottitis: the Toronto hospital experience","volume":"27","author":"Solomon P","year":"1998","journal-title":"J Otolarygol"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1988.03720040055027"},{"key":"e_1_2_6_9_1","first-page":"23","article-title":"Acute epiglottitis in adults","volume":"10","author":"Black MJ","year":"1981","journal-title":"J Otolaryngol"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.104.3.964"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199308000-00002"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03036974"},{"key":"e_1_2_6_13_1","first-page":"194","article-title":"Epiglottitis: adult and pediatric comparisons","volume":"17","author":"Murrage KJ","year":"1988","journal-title":"J Otolaryngol"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199002000-00014"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199801000-00034"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100130087"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198503000-00009"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100117487"},{"key":"e_1_2_6_19_1","first-page":"29","article-title":"Acute epiglottitis in adults: a review of 40 cases","volume":"25","author":"Lau KK","year":"1990","journal-title":"J Taiwan Otolaryngological Society"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0194599805000902?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2005.01.011","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0194599805000902?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.otohns.2005.01.011","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2005.01.011","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T11:42:51Z","timestamp":1760960571000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2005.01.011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,5]]}},"alternative-id":["10.1016\/j.otohns.2005.01.011"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2005.01.011","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,5]]},"assertion":[{"value":"2016-05-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}