{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T16:38:21Z","timestamp":1773765501259,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":4064,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2005,4]]},"abstract":"<jats:sec><jats:title>OBJECTIVE:<\/jats:title><jats:p>To correlate the levels of interleukins 1 \u03b2, 3, 4, and 5 before and after surgery and compare the levels between patients with and without recurrence of nasal polyposis.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND SETTING:<\/jats:title><jats:p>Thirty\u2010nine patients with NP were selected, 13 of them allergic and 26\u00a0nonallergic. A control group of 11\u00a0individuals was also studied. The concentrations of interleukins were measured by enzyme\u2010linked immunosorbent assay.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS:<\/jats:title><jats:p>There was a higher incidence of NP after the fourth decade of life and among men. The clinical symptoms were similar in both groups of patients with nasal polyposis and characterized by nasal obstruction and anosmia. A significant reduction of all interleukins studied was observed after surgical treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION:<\/jats:title><jats:p>Levels of interleukins 1\u03b2, 3, 4, and 5 were significantly reduced after surgery and the levels of interleukins 1\u03b2 and 5 were significantly lower in patients without recurrence of nasal polyposis after surgery when compared to those with recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2005.01.014","type":"journal-article","created":{"date-parts":[[2005,4,2]],"date-time":"2005-04-02T07:14:54Z","timestamp":1112426094000},"page":"613-619","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Expression of Interleukins in Patients with Nasal Polyposis"],"prefix":"10.1002","volume":"132","author":[{"given":"Richard Louis","family":"Voegels","sequence":"first","affiliation":[{"name":"Division of Otorhinolaryngological Clinic Clinical 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