{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T09:24:13Z","timestamp":1778837053523,"version":"3.51.4"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":4064,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100009925","name":"Villadsen Family Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2005,4]]},"abstract":"<jats:sec><jats:title>BACKGROUND:<\/jats:title><jats:p>To evaluate the feasibility of endoscopic surgery with image guidance in the treatment of inverted papillomas.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND SETTING:<\/jats:title><jats:p>This prospective cohort study comprised 42 consecutive patients with biopsy\u2010confirmed inverted papillomas that were diagnosed between 1998 and 2003. All patients were treated by the first author (C.B.). Image guidance based on preacquired CT scans of the patients was used to assist the surgeon aiming at endoscopic resection of inverted papilloma. The success of the surgery was judged primarily by the recurrence rate and the treatment morbidity.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS:<\/jats:title><jats:p>The study group consisted of 30\u00a0males and 12 females with a median age of 61 years. The follow\u2010up period ranged from 9\u00a0months to 69\u00a0months (median, 37\u00a0months). The only additional procedure performed was the Caldwell\u2010Luc procedure (8 cases). Recurrence was diagnosed in 10 cases (24%), all in the original tumor site. Eight of these had undergone previous surgery for inverted papilloma. The recurrences were predominantly located in the maxillary or in the frontal sinus (8 cases). In 2 cases, the recurrence was simply removed endoscopically while performing the biopsy procedure. All recurrences were identified within the first 9\u00a0months. Associated malignancy was not shown. No severe complications occurred.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS:<\/jats:title><jats:p>A treatment based on endoscopic resection with image guidance appears to offer a safe treatment modality of inverted papilloma with insignificant morbidity. Predominantly cases with nonmedial involvement of the maxillary sinus still require a supplement with the Caldwell Luc procedure. Although all the recurrences were found within 9\u00a0months postoperatively, later recurrences cannot be excluded. Long\u2010term follow\u2010up is recommended.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2005.01.016","type":"journal-article","created":{"date-parts":[[2005,4,2]],"date-time":"2005-04-02T07:14:54Z","timestamp":1112426094000},"page":"602-607","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Endoscopic Surgery of Inverted Papillomas under Image Guidance\u2014A Prospective Study of 42 Consecutive Cases at a Danish University Clinic"],"prefix":"10.1002","volume":"132","author":[{"given":"Christian","family":"Von Buchwald","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Rigshospitalet University Hospital of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anders S.","family":"Von Larsen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Rigshospitalet University Hospital of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,17]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/978-3-642-84474-4","volume-title":"Histological typing of tumours of the upper respiratory tract and ear. World Health Organization","author":"Shanmugaratnam KSL","year":"1991"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199501000-00016"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200309000-00026"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200309000-00025"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200108000-00015"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200001000-00008"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200402000-00003"},{"key":"e_1_2_1_9_1","first-page":"1","article-title":"Image guided surgery of paranasal sinuses and anterior skull base\u2014five years experience with the InstaTrak\u2010System","volume":"40","author":"Koele W","year":"2002","journal-title":"Rhinology"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240201600403"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.5541121301"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200006000-00015"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199208000-00012"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200402000-00002"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200311000-00024"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200304000-00031"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0194599805000951?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2005.01.016","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0194599805000951?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2005.01.016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T09:27:53Z","timestamp":1760952473000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2005.01.016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,4]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,4]]}},"alternative-id":["10.1016\/j.otohns.2005.01.016"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2005.01.016","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,4]]},"assertion":[{"value":"2016-05-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}