{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:02:17Z","timestamp":1789948937863,"version":"4.0.1"},"reference-count":6,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":4064,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2005,4]]},"abstract":"<jats:sec><jats:title>OBJECTIVES:<\/jats:title><jats:p>TNO\u2010AZL Preschool Quality of Life Questionnaire (TAPQOL) is one of the few instruments designed to assess health\u2010related quality of life in preschool children but its applicability to otolaryngology is unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND SETTING:<\/jats:title><jats:p>We studied a consecutive series of children aged 1 to 5 years referred to hospital with recurrent sore throats, recurrent acute otitis media, or otitis media with effusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS:<\/jats:title><jats:p>TAPQOL domain scores were not influenced by age, sex, or socio\u2010economic class, but correlated with markers of disease severity (frequency of sore throat or pyrexia, time off school), ear\u2010related handicap (assessed with the OM6 questionnaire), and other measures of health\u2010related quality of life (visual analogue scale, 5\u2010point rating scale and the Health Utilities Index mark III). Comparison with published data from healthy children suggests that these common otolaryngologic problems have a large impact on a child's quality of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS:<\/jats:title><jats:p>TAPQOL seems to be appropriate for use in this context. Marked ceiling effects in some domains, however, may limit their sensitivity.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2005.01.028","type":"journal-article","created":{"date-parts":[[2005,4,2]],"date-time":"2005-04-02T07:14:54Z","timestamp":1112426094000},"page":"647-652","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Measuring Quality of Life in Preschool Children with Sore Throats and Otitis Media Using the Tapqol Questionnaire"],"prefix":"10.1002","volume":"132","author":[{"given":"Haytham","family":"Kubba","sequence":"first","affiliation":[{"name":"MRC Institute for Hearing Research (Scottish Section) Glasgow Royal Infirmary Glasgow Scotland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iain R. 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