{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T21:47:40Z","timestamp":1767649660184,"version":"build-2065373602"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":3973,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"publisher","award":["92\u20102314\u2010B\u2010195\u2010024"],"award-info":[{"award-number":["92\u20102314\u2010B\u2010195\u2010024"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2005,7]]},"abstract":"<jats:sec><jats:title>OBJECTIVES:<\/jats:title><jats:p>To evaluate the effects of successful laser\u2010assisted uvulopalatoplasty (LAUP) on cardiopulmonary exercise testing (CPET) in patients with obstructive sleep apnea syndrome (OSAS).<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND SETTING:<\/jats:title><jats:p>Twenty\u2010five subjects with moderately severe or severe OSAS who desired LAUP were enrolled. All patients had an overnight sleep study and CPET before and 3\u00a0months after LAUP. Patients were divided into 2\u00a0groups based on the success (group I) or failure (group II) of LAUP to improve their sleep apnea.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS:<\/jats:title><jats:p>Successful LAUP in group I was followed by improvement in right ventricular ejection fraction, maximal work rate (WRmax), VO<jats:sub>2<\/jats:sub>max\/kg, anaerobic threshold, oxygen pulse, and a lower breathing reserve. CPET results were unchanged after LAUP in group II subjects.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION:<\/jats:title><jats:p>Patients with OSAS before LAUP had abnormal CPET as reflected by low VO2peak\/kg, WRmax, anaerobic threshold, and oxygen pulse. 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