{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:33:32Z","timestamp":1764995612795,"version":"build-2065373602"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":3942,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2005,8]]},"abstract":"<jats:sec><jats:title>Objective:<\/jats:title><jats:p>This study was designed to compare desflurane and sevoflurane anesthesia for middle ear microsurgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design:<\/jats:title><jats:p>One hundred healthy adults undergoing middle ear surgery were assigned to receive either desflurane or sevoflurane as their anesthetic. Intraoperative hemodynamics and BIS numbers were recorded. Hemodynamics, pain, nausea\/vomiting, discharge readiness, and other parameters were compared postoperatively and 24 hours later.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>No intraoperative differences were noted except in BIS scores which trended lower with desflurane. PACU blood pressures were higher after desflurane but pain scores, nausea\/vomiting, rescue anti\u2010emetics, recovery scores, and discharge times were similar. A significant difference was noted in anesthetic costs (desflurane &gt; sevoflurane), and in patients with the lowest BIS scores associated with more nausea\/vomiting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Both anesthetics may be used for ototic surgery but propofol anesthesia should still be considered in patients with a history of emetic sequelae.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance:<\/jats:title><jats:p>Short\u2010acting inhalational anesthetics produce excellent operating conditions and reduce costs for otologic surgery.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2005.04.011","type":"journal-article","created":{"date-parts":[[2005,8,7]],"date-time":"2005-08-07T09:47:55Z","timestamp":1123408075000},"page":"269-274","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Standard Anesthetic Technique for Middle Ear Surgical Procedures: A Comparison of Desflurane and Sevoflurane"],"prefix":"10.1002","volume":"133","author":[{"given":"W. 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