{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T19:34:46Z","timestamp":1773084886659,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":3881,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2005,10]]},"abstract":"<jats:sec><jats:title>OBJECTIVE:<\/jats:title><jats:p>Patients with acid reflux can occasionally present with atypical symptoms such as globus pharyngeus, constant throat clearing, chronic cough, hoarseness, catarrh, choking episodes or asthma\u2010like symptoms. The aim of this survey was to determine whether general practitioners are aware of the atypical manifestations of reflux and the differences in treatment between laryngopharyngeal reflux and gastroesophageal reflux.<\/jats:p><\/jats:sec><jats:sec><jats:title>DESIGN:<\/jats:title><jats:p>Questionnaire Survey.<\/jats:p><\/jats:sec><jats:sec><jats:title>SETTING:<\/jats:title><jats:p>Primary Care<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS:<\/jats:title><jats:p>One hundred and sixty general practitioners who routinely refer patients to our Department of Otolaryngology were selected and a postal survey was conducted. One hundred and fifty of these responded (94% response rate). The commonest symptoms for which proton pump inhibitors are prescribed are heartburn (65%), followed by a combination of heartburn and other symptoms (15%), chronic cough (4%), choking episodes (4%), asthmalike symptoms (3%), hoarseness (2%), globus (2%), catarrh (1%), dysphagia (1.5%), frequent throat clearing (1.5%), halitosis and\/or bitter taste (1%).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS:<\/jats:title><jats:p>Our results suggest that the majority of the general practitioners surveyed are unaware of the entity laryngopharyngeal reflux or reflux symptom index. More awareness is required in the primary care setting for early recognition of patients with suspected laryngopharyngeal reflux.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2005.06.013","type":"journal-article","created":{"date-parts":[[2005,10,18]],"date-time":"2005-10-18T16:49:23Z","timestamp":1129654163000},"page":"505-508","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Awareness of General Practitioners towards Treatment of Laryngopharyngeal Reflux: A British Survey"],"prefix":"10.1002","volume":"133","author":[{"given":"P.D.","family":"Karkos","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Countess of Chester Hospital Chester UK"},{"name":"Department of Otolaryngology The Freeman Hospital Newcastle upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Countess of Chester Hospital Chester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.H.","family":"Temple","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Countess of Chester Hospital Chester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.J.","family":"Issing","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology The Freeman Hospital Newcastle upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,17]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"7","article-title":"Laryngopharyngeal reflux is different from classic gastroesophageal reflux disease","volume":"9","author":"Koufman JA","year":"2002","journal-title":"Ear Nose Throat J"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/014107680309601002"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365529509090292"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200205000-00019"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(02)00097-8"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.1991.101.s53.1"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-200405000-00002"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200311000-00013"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2001.03681.x"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520310001860"},{"key":"e_1_2_1_12_1","first-page":"A99","article-title":"Long term follow\u2010up of patients treated with acid suppressive therapy for suspected reflux related laryngeal signs and symptoms","volume":"126","author":"Swoger JM","year":"2004","journal-title":"Gastroenterology"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/000164800454468"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2002.125760"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(96)80001-4"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0194599805013173?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2005.06.013","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0194599805013173?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2005.06.013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:08:04Z","timestamp":1760954884000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2005.06.013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,10]]}},"alternative-id":["10.1016\/j.otohns.2005.06.013"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2005.06.013","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,10]]},"assertion":[{"value":"2016-05-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}