{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T03:14:43Z","timestamp":1791429283299,"version":"4.3.3"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":3850,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2005,11]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>To study the clinical course and outcome of deep neck infections (DNI), with special emphasis on microbiology and histopathology.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN<\/jats:title><jats:p>Two hundred thirty\u2010four patients with DNIs were included in this study. Patients with peritonsillar or dental infections, infections arising from salivary glands, as well as subjects with abscesses caused by neck trauma were excluded.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>Clinical analysis of all patients with DNIs who were treated between January 1, 1997 and May 31, 2005\u00a0in a single center.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>In 13 patients, the DNI was the first manifestation of a malignant tumor. In 17 cases, the DNI was associated with cat\u2010scratch disease (CSD). Six patients suffered from tuberculosis, and in another 7, an infected lateral cleft cyst was found. In 176 patients, the origin of DNI remained unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>Our results demonstrate that CSD, tuberculosis, and malignant tumors must be considered as possible causes of DNIs. The current study represents one of the largest series of DNIs in the modern medical literature.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2005.07.001","type":"journal-article","created":{"date-parts":[[2005,11,5]],"date-time":"2005-11-05T07:38:11Z","timestamp":1131176291000},"page":"709-714","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":105,"title":["Spectrum and Management of Deep Neck Space Infections: An 8\u2010Year Experience of 234 Cases"],"prefix":"10.1002","volume":"133","author":[{"given":"Gerd J\u00dcRgen","family":"Ridder","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Institute of Medical Microbiology and Hygiene University of Freiburg Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Technau\u2010Ihling","sequence":"additional","affiliation":[{"name":"Department of Pathology Institute of Medical Microbiology and Hygiene University of Freiburg Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Sander","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Hygiene Institute of Medical Microbiology and Hygiene University of Freiburg Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten Christof","family":"Boedeker","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Institute of Medical Microbiology and Hygiene University of Freiburg Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,17]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(96)90013-7"},{"key":"e_1_2_5_3_1","first-page":"1700","volume-title":"Otolaryngology\u2014Otol Head and Neck Surgery","author":"Weed HG","year":"1998"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940111001111"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100126106"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59989570270-9"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-003-0634-7"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59989770345-0"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/CDLI.5.4.486-490.1998"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.4.993-997.1999"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1086\/342058"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200108000-00018"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0347(200102)23:2<126::AID-HED1007>3.0.CO;2-N"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199702000-00002"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.09.019"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2000.110613"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.1965.tb04454.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100135273"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100143191"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459989411100608"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199806000-00002"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S019459980501421X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2005.07.001","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S019459980501421X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.otohns.2005.07.001","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2005.07.001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:40:02Z","timestamp":1760956802000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2005.07.001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["10.1016\/j.otohns.2005.07.001"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2005.07.001","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,11]]},"assertion":[{"value":"2016-05-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}