{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:19:29Z","timestamp":1767651569532,"version":"build-2065373602"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":3820,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2005,12]]},"abstract":"<jats:sec><jats:title>BACKGROUND AND OBJECTIVE<\/jats:title><jats:p>To evaluate the ability of optical coherence tomography (OCT) (a noncontact, high\u2010resolution imaging technique that generates detailed cross\u2010sectional images of tissue structure) to image and document acute response to trauma in the larynx.<\/jats:p><\/jats:sec><jats:sec><jats:title>MATERIALS AND METHODS<\/jats:title><jats:p>Porcine larynges were dissected to expose the vocal cords. Vocal cords were imaged with 1310\u00a0nanometer (nm) light source with a bandwidth of 75\u00a0nm at 1 frame\/second (s). Vocal cord injuries were simulated by applying topical phenolic acid, injecting titanium dioxide into the submucosa, and carbon dioxide laser irradiation.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>The epithelium, basement membrane, and lamina propria were clearly delineated, and the effect of each intervention could be monitored as lesions progressed. The OCT image corresponded closely with histology.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>OCT is a powerful imaging tool with the potential for use in real time and has potential for multiple clinical applications in the larynx.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2005.09.013","type":"journal-article","created":{"date-parts":[[2005,12,20]],"date-time":"2005-12-20T10:21:35Z","timestamp":1135074095000},"page":"845-850","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Measurement of Morphologic Changes Induced by Trauma with the Use of Coherence Tomography in Porcine Vocal Cords"],"prefix":"10.1002","volume":"133","author":[{"given":"Nader A.","family":"Nassif","sequence":"first","affiliation":[{"name":"Department of Physics and Astronomy University of California Irvine California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William 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