{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:44:13Z","timestamp":1761007453238,"version":"build-2065373602"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":3730,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:sec><jats:title>OBJECTIVES<\/jats:title><jats:p>This study aimed to investigate the prevalence of optic nerve protrusion (ONP) and its clinical indicators by using sinus computed tomography (CT) scan.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN<\/jats:title><jats:p>Sinus CT scans of 260 consecutive patients with chronic inflammatory sinus disease were reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>The prevalence of ONP in our study population was 28%. Nineteen percent of the optic nerves protruded into the sphenoid sinuses including indentation of the sinus wall (12%) and coursing through the sphenoid sinus (8%). In the presence of contralateral ONP and\/or ipsilateral anterior clinoid process pneumatization, the chance of ONP occurrence was significantly higher (both <jats:italic>P<\/jats:italic> &lt; 0.01). They were reliable indicators of ONP (<jats:italic>R<\/jats:italic> <jats:sup>2<\/jats:sup> = 0.47, <jats:italic>P<\/jats:italic> &lt; 0.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>ONP is a common anatomic variation observed in patients with chronic inflammatory sinus disease. To reduce optic nerve damage in surgeries, the presence of ONP according to sinus CT scans and the intraoperative findings should be carefully evaluated.<\/jats:p><jats:p>EBM rating: C\u20104<\/jats:p><jats:p>\u00a9 2006 American Academy of Otolaryngology\u2010Head and Neck Surgery Foundation, Inc. All rights reserved.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2005.10.036","type":"journal-article","created":{"date-parts":[[2006,2,22]],"date-time":"2006-02-22T07:28:35Z","timestamp":1140593315000},"page":"499-505","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Surgical Consideration to Optic Nerve Protrusion According to Sinus Computed Tomography"],"prefix":"10.1002","volume":"134","author":[{"given":"Ying\u2010Lin","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Chang Gung Memorial Hospital Department of Medical Imaging Buddhist Tzu Chi General Hospital Taipei Taiwan Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li\u2010Ang","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Chang Gung Memorial Hospital Department of Medical Imaging Buddhist Tzu Chi General Hospital Taipei Taiwan Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kun\u2010Eng","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,17]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_5_2_1","DOI":"10.1067\/mhn.2002.125759"},{"doi-asserted-by":"publisher","key":"e_1_2_5_3_1","DOI":"10.1002\/lary.1991.101.4.349"},{"doi-asserted-by":"publisher","key":"e_1_2_5_4_1","DOI":"10.1016\/S0161-6420(90)32535-6"},{"doi-asserted-by":"publisher","key":"e_1_2_5_5_1","DOI":"10.1288\/00005537-197210000-00004"},{"key":"e_1_2_5_6_1","first-page":"669","article-title":"Relationship of the optic nerve to the posterior paranasal sinuses: A CT anatomy study.","volume":"17","author":"Delano MC","year":"1996","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_5_7_1","first-page":"407","article-title":"Related structures of the lateral sphenoid wall anatomy studies in CT and MRI.","volume":"16","author":"Liu S","year":"2002","journal-title":"Lin Chuang Er Bi Yan Hou Ke Za Zhi"},{"doi-asserted-by":"publisher","key":"e_1_2_5_8_1","DOI":"10.1177\/019459988709600405"},{"doi-asserted-by":"publisher","key":"e_1_2_5_9_1","DOI":"10.1007\/BF00593511"},{"doi-asserted-by":"publisher","key":"e_1_2_5_10_1","DOI":"10.1007\/s003300051016"},{"doi-asserted-by":"publisher","key":"e_1_2_5_11_1","DOI":"10.1016\/j.otohns.2004.07.013"},{"doi-asserted-by":"publisher","key":"e_1_2_5_12_1","DOI":"10.1097\/00005537-199803000-00020"},{"key":"e_1_2_5_13_1","first-page":"85","article-title":"The optic nerves and their relations in the sphenoid region.","volume":"22","author":"Mellinger WJ","year":"1937","journal-title":"Pacific Coast Oto Ophth Soc"},{"doi-asserted-by":"publisher","key":"e_1_2_5_14_1","DOI":"10.1097\/00005537-200406000-00006"},{"key":"e_1_2_5_15_1","first-page":"1","article-title":"The recovery potential of the optic nerve.","volume":"105","author":"Sofferman RA","year":"1995","journal-title":"Laryngoscope"},{"key":"e_1_2_5_16_1","first-page":"88","volume-title":"Clinical Anatomy of the Nose, Nasal Cavity and Paranasal Sinuses.","author":"Lang J","year":"1989"},{"doi-asserted-by":"publisher","key":"e_1_2_5_17_1","DOI":"10.1177\/014556130308200314"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2005.10.036","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.otohns.2005.10.036","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2005.10.036","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:24:37Z","timestamp":1760966677000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2005.10.036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,3]]}},"alternative-id":["10.1016\/j.otohns.2005.10.036"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2005.10.036","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[2006,3]]},"assertion":[{"value":"2016-05-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}