{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T10:30:20Z","timestamp":1761647420778,"version":"build-2065373602"},"reference-count":3,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":3608,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2006,7]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>A review of the treatment of pediatric acute mastoiditis requiring surgical intervention managed with and without PICC therapy postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND SETTING<\/jats:title><jats:p>Retrospective study of 42 cases from 1989 to 2004 treated at a regional children's hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Sixteen patients received postoperative PICC therapy and 26 received a course of oral antibiotics. The PICC group received on average 12.12\u00a0days of intravenous antibiotics compared to only 3.53\u00a0days for the non\u2010PICC group (<jats:italic>P<\/jats:italic> &lt; 0.001). No differences were observed between the two groups in treatment outcomes. One patient from each group required rehospitalization. One minor complication was experienced in a patient in the PICC group. There were no surgical complications. The total cost for outpatient PICC therapy increased treatment costs by approximately $1500 to $2500.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>Oral antibiotic therapy is sufficient after surgical intervention for acute pediatric suppurative mastoiditis without intracranial complications and does not result in adverse treatment outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>SIGNIFICANCE<\/jats:title><jats:p>Use of PICC therapy after surgical intervention for mastoiditis should be limited.<\/jats:p><jats:p>EBM rating: B\u20103b<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2006.02.016","type":"journal-article","created":{"date-parts":[[2006,7,1]],"date-time":"2006-07-01T09:40:19Z","timestamp":1151746819000},"page":"106-110","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Treatment of Pediatric Suppurative Mastoiditis: Is Peripherally Inserted Central Catheter (PICC) Antibiotic Therapy Necessary?"],"prefix":"10.1002","volume":"135","author":[{"given":"A. Moore","family":"Jeremy","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery University of Kansas School of Medicine Kansas City Kansas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. Wei","family":"Julie","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery University of Kansas School of Medicine Kansas City Kansas"},{"name":"Section of Otolaryngology\u2014Head and Neck Surgery Children's Mercy Hospitals and Clinic Kansas City Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Smith","family":"Holly","sequence":"additional","affiliation":[{"name":"Center for Biostatistics and Advanced Informatics University of Kansas Medical Center Kansas City Kansas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. Mayo","family":"Matthew","sequence":"additional","affiliation":[{"name":"Center for Biostatistics and Advanced Informatics University of Kansas Medical Center Kansas City Kansas"},{"name":"Preventive Medicine and Public Health University of Kansas School of Medicine Kansas City Kansas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,17]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_7_2_1","DOI":"10.1016\/0165-5876(92)90022-H"},{"key":"e_1_2_7_3_1","first-page":"280","article-title":"Pediatric peripherally inserted central catheter program report. A summary of 4536 catheter days","volume":"18","author":"Frey AM","year":"1995","journal-title":"J Intraven Nurs"},{"doi-asserted-by":"publisher","key":"e_1_2_7_4_1","DOI":"10.1016\/S0002-9610(98)00121-4"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2006.02.016","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.otohns.2006.02.016","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2006.02.016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:42:18Z","timestamp":1760956938000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2006.02.016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7]]},"references-count":3,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,7]]}},"alternative-id":["10.1016\/j.otohns.2006.02.016"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2006.02.016","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[2006,7]]},"assertion":[{"value":"2016-05-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}