{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:32:25Z","timestamp":1761006745137,"version":"build-2065373602"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,11,21]],"date-time":"2016-11-21T00:00:00Z","timestamp":1479686400000},"content-version":"vor","delay-in-days":3704,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>To evaluate the short\u2010term safety and efficacy of palatal implants in patients with mild and moderate obstructive sleep apnea (OSA).<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND SETTING<\/jats:title><jats:p>A prospective, non\u2010randomized study conducted at 5 clinical sites. Three polyester implants were placed in the soft palate under local anesthesia during a single\u2010stage office procedure. Polysomnography was conducted at baseline and 90\u00a0days post\u2010procedure. Subjective quality of life data were collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Fifty\u2010three patients were evaluated; the apnea hypopnea index (AHI) decreased from 25.0 \u00b1 13.9 to 22.0 \u00b1 14.8 events\/hour (<jats:italic>P<\/jats:italic> = 0.05). The Epworth Sleepiness Scale (ESS) decreased from 11.0 \u00b1 5.1 to 6.9 \u00b1 4.5 (<jats:italic>P<\/jats:italic> &lt; 0.001), and the snore score decreased from 7.9 \u00b1 2.1 to 4.0 \u00b1 3.0 (<jats:italic>P<\/jats:italic> &lt; 0.001). No serious complications occurred during the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Palatal implants can be an effective initial low morbidity treatment option for patients diagnosed with mild to moderate OSA.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2006.02.020","type":"journal-article","created":{"date-parts":[[2006,9,28]],"date-time":"2006-09-28T08:34:42Z","timestamp":1159432482000},"page":"549-554","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Palatal Implants: A New Approach for the Treatment of Obstructive Sleep Apnea"],"prefix":"10.1002","volume":"135","author":[{"given":"Regina P.","family":"Walker","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Loyola University Medical Center Maywood IL"},{"name":"Hinsdale Hospital Hinsdale IL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard L.","family":"Levine","sequence":"additional","affiliation":[{"name":"Cleveland Nasal Sinus and Sleep Center Head and Neck Institute Marymount Outpatient Care Center Cleveland Clinic Foundation Cleveland OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin L.","family":"Hopp","sequence":"additional","affiliation":[{"name":"Cedars\u2010Sinai Medical Center Los Angeles CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Greene","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Florida Naples FL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenny","family":"Pang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Medical College of Georgia Augusta GA"},{"name":"Tan Tock Seng Hospital Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,11,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4636(199611)32:3<293::AID-JBM2>3.0.CO;2-N"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820220705"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1006\/jsre.1994.1058"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0142-9612(83)90049-2"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1975.01360180039008"},{"key":"e_1_2_6_7_1","first-page":"93","article-title":"Biostability and morphology of tissue reaction of some synthetic polymers","author":"Waitzova D","year":"1986","journal-title":"Polim Med"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.120.1.156"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016480310017090"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.09.015"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-004-0791-3"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.130.6.753"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199912000-00002"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199409000-00017"},{"key":"e_1_2_6_15_1","first-page":"639","article-title":"Laser\u2010assisted uvulopalatoplasty. Six and eighteen month results","volume":"221","author":"Wareing M","year":"1998","journal-title":"J Otolaryngol"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2000.102183"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/19.2.156"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.26336"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.11.001"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2006.02.020","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.otohns.2006.02.020","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2006.02.020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:05:46Z","timestamp":1760954746000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2006.02.020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["10.1016\/j.otohns.2006.02.020"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2006.02.020","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[2006,10]]},"assertion":[{"value":"2016-11-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}