{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:31:33Z","timestamp":1791909093770,"version":"4.3.4"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":3638,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2006,6]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>Present and evaluate the currently available literature reporting on the effectiveness of adenotonsillectomy (T\/A) in treating obstructive sleep apnea\/hypopnea syndrome (OSAHS) in uncomplicated pediatric patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>STUDY DESIGN AND SETTING<\/jats:title>\n                    <jats:p>Systematic review of the literature and meta\u2010analysis of the reduction of the polysomnogram (PSG)\u2010measured Apnea Hypopnea Index (AHI events\/hour) resulting from T\/A and the overall success rate of T\/A in normalizing PSG measurements (%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      Fourteen studies met the inclusion criteria. Mean sample size was 28. All were case series (level 4 evidence). The summary change in AHI was a reduction of 13.92 events per hour (random effects model 95% CI 10.05\u201317.79,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001) from T\/A. The summary success rate of T\/A in normalizing PSG was 82.9% (random effects model 95% CI 76.2%\u201389.5%,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION\/SIGNIFICANCE<\/jats:title>\n                    <jats:p>T\/A is effective in the treatment of OSAHS. However, success rates are far below 100%, which could have far\u2010reaching pediatric public health consequences.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.otohns.2006.02.033","type":"journal-article","created":{"date-parts":[[2006,5,26]],"date-time":"2006-05-26T07:27:42Z","timestamp":1148628462000},"page":"979-984","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":338,"title":["The Effectiveness of Tonsillectomy and Adenoidectomy in the Treatment of Pediatric Obstructive Sleep Apnea\/Hypopnea Syndrome: A Meta\u2010Analysis"],"prefix":"10.1002","volume":"134","author":[{"given":"Scott E.","family":"Brietzke","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Walter Reed Army Medical Center Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Gallagher","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Walter Reed Army Medical Center Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1389-9457(03)00100-X"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.120.6.1930"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1526-0542(04)90066-8"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949009900305"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.moo.0000186076.53986.71"},{"key":"e_1_2_6_7_1","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1002\/9780470693926","volume-title":"Systematic reviews in health care: meta\u2010analysis in health care","author":"Egger M","year":"2001"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1980.00790320044011"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.71.5.737"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1995.01890050023005"},{"key":"e_1_2_6_11_1","first-page":"231","article-title":"Effect of surgery on obstructive sleep apnea","volume":"523","author":"Nashimura T","year":"1996","journal-title":"Acta Otolaryngol Suppl"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(97)00065-7"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(98)00047-0"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(98)70377-8"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(99)70331-8"},{"key":"e_1_2_6_16_1","first-page":"893","article-title":"Objektiver nutzen der adenotonsillektomie biem kin","volume":"88","author":"Nuyens MR","year":"1999","journal-title":"Praxis"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.126.4.481"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0034-72992002000300003"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.3.948"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2003.08.034"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200401000-00024"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.07.002"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2006.02.033","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.otohns.2006.02.033","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2006.02.033","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T08:56:35Z","timestamp":1760950595000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2006.02.033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["10.1016\/j.otohns.2006.02.033"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2006.02.033","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,6]]},"assertion":[{"value":"2016-05-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}