{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T18:06:26Z","timestamp":1793383586071,"version":"4.5.0"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":3577,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2006,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the effect of concurrent uvulopalatopha\u2010ryngoplasty and hypopharyngeal procedures in obstructive sleep apnea (OSA) patients with diffuse airway narrowing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design and Setting<\/jats:title><jats:p>Forty\u2010eight patients were treated surgically by a single surgeon in private practice over 2 years. Symptoms, Epworth score, and polysomnographic outcome were assessed preoperatively and postoperatively. The Friedman staging system was applied. UPPP with genioglossus advancement, hyoid suspension, or radiofrequency treatment was carried out.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 37 patients with complete data, the average apnea\u2010hypopnea index (AHI) was reduced from 46.5 \u00b1 24.8 to 14.9 \u00b1 16.8. The Epworth score was reduced from 12.1 \u00b1 4.9 to 6.7 \u00b1 3.7. Most patients reported improved sleep quality, alertness, memory, concentration, and mood.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Successful outcome, defined by symptom and AHI reduction, was achieved with multilevel surgery for most patients with advanced Friedman stages 2 and 3.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>Multilevel surgery seems effective in treating severe OSA patients with diffuse airway narrowing.<\/jats:p><jats:p><jats:bold>EBM rating: C\u20104<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2006.03.029","type":"journal-article","created":{"date-parts":[[2006,8,7]],"date-time":"2006-08-07T10:36:57Z","timestamp":1154947017000},"page":"258-264","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Palatal and tongue base surgery for surgical treatment of obstructive sleep apnea: A prospective study"],"prefix":"10.1002","volume":"135","author":[{"given":"Ofer","family":"Jacobowitz","sequence":"first","affiliation":[{"name":"Columbia New York Presbyterian Department of Otolaryngology Middletown New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199304293281704"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00132580-200209000-00006"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2003.007187"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.11.001"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/147.4.887"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2105124"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/19.2.156"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(10)80412-4"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1053\/hn.1999.v120.a96956"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.01.012"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200403000-00013"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2002.126477"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/19.7.593"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59980300711-3"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2000.106707"},{"key":"e_1_2_7_17_1","first-page":"835","article-title":"An instrument to measure functional status outcomes for disorders of excessive sleepiness","volume":"20","author":"Weaver TE","year":"1997","journal-title":"Sleep"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2006.03.029","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.otohns.2006.03.029","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2006.03.029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:50:55Z","timestamp":1760968255000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2006.03.029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,8]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,8]]}},"alternative-id":["10.1016\/j.otohns.2006.03.029"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2006.03.029","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,8]]},"assertion":[{"value":"2016-05-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}