{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T03:18:06Z","timestamp":1769311086137,"version":"3.49.0"},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":3546,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p><jats:italic>Corynebacterium mucifaciens<\/jats:italic> was first proposed as a novel <jats:italic>Corynebacterium<\/jats:italic> species in 1997. This report describes our experience with the unexpectedly frequent isolation of <jats:italic>C mucifaciens.<\/jats:italic><\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>By using agar supplemented with several antibiotics, microbiological studies were performed on specimens collected from the ear and nose.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>A primary and secondary referral hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The organisms grew slowly. Five strains of <jats:italic>C mucifaciens<\/jats:italic> were found in specimens of middle ear effusion (MEE) from patients with otitis media with effusion (OME), and four strains were isolated from the nasal polyps and nasal discharge of patients with chronic sinusitis (CRS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:italic>C mucifaciens<\/jats:italic> was isolated from nine otorhinological specimens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>This is the first report about the isolation of <jats:italic>C mucifaciens<\/jats:italic> from MEE, nasal polyps, and nasal discharge. Although its pathogenetic role is unknown, the characteristics of this microorganism might make it a potential cause of OME and\/or CRS, so further studies are necessary.<\/jats:p><jats:p><jats:bold>EBM rating: C\u20104<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2006.05.017","type":"journal-article","created":{"date-parts":[[2006,9,2]],"date-time":"2006-09-02T07:22:32Z","timestamp":1157181752000},"page":"392-396","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Unusual Corynebacterium mucifaciens isolated from ear and nasal specimens"],"prefix":"10.1002","volume":"135","author":[{"given":"Setsuko","family":"Morinaka","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Kobe Japanpost Hospital Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manabu","family":"Kurokawa","sequence":"additional","affiliation":[{"name":"Department of Microbiology Kobe Institute of Health Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masafumi","family":"Nukina","sequence":"additional","affiliation":[{"name":"Department of Microbiology Kobe Institute of Health Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Research Institute Osaka Medical Center for Cancer and Cardiovascular Diseases Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,17]]},"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2006.05.017","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.otohns.2006.05.017","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2006.05.017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:21:47Z","timestamp":1760970107000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2006.05.017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,9]]}},"alternative-id":["10.1016\/j.otohns.2006.05.017"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2006.05.017","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,9]]},"assertion":[{"value":"2016-05-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}