{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T03:03:02Z","timestamp":1770433382026,"version":"3.49.0"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":3455,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:sec><jats:title>OBJECTIVES<\/jats:title><jats:p>To describe the results of a 1\u00a0phase surgical procedure for the treatment of severe obstructive sleep apnea (OSA) attributable to tongue base obstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND SETTING<\/jats:title><jats:p>A retrospective nonrandomized study at S Orsola Malpighi University Hospital of Bologna, Italy.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>Ten male patients affected by severe OSA (mean apnea\/hypopnea index [AHI] of 54.7), underwent uvulopalatopharyngoplasty (UPPP) associated with tongue base reduction and hyoepiglottoplasty (TBRHE). The indications to this surgical procedure were based on the presence of hyolingual abnormalities and absence of craniofacial deficiencies determined by preoperative assessment.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Mean AHI decreased from 54.7 + 11.5 to 9.4 + 5.4 whereas the mean low SaO<jats:sub>2<\/jats:sub> value went from 77% + 6.2 to 90.7% + 3 and the time of sleep with SaO<jats:sub>2<\/jats:sub> &lt; 90% improved from 53% + 17.2 to 7.3% + 8. The overall success rate was 100%.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS AND SIGNIFICANCE<\/jats:title><jats:p>TBRHE is an effective and safe treatment in patients with severe OSA attributable to tongue base obstruction and in absence of craniofacial deficiencies.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2006.06.1253","type":"journal-article","created":{"date-parts":[[2006,11,30]],"date-time":"2006-11-30T09:44:54Z","timestamp":1164879894000},"page":"906-910","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["One\u2010phase management of severe obstructive sleep apnea: Tongue base reduction with hyoepiglottoplasty plus uvulopalatopharyngoplasty"],"prefix":"10.1002","volume":"135","author":[{"given":"Giovanni","family":"Sorrenti","sequence":"first","affiliation":[{"name":"ENT Department S Orsola\u2010Malpighi Hospital Bologna University Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ottavio","family":"Piccin","sequence":"additional","affiliation":[{"name":"ENT Department S Orsola\u2010Malpighi Hospital Bologna University Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanna","family":"Mondini","sequence":"additional","affiliation":[{"name":"Sleep Unit S Orsola\u2010Malpighi Hospital Bologna University Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto Rinaldi","family":"Ceroni","sequence":"additional","affiliation":[{"name":"ENT Department S Orsola\u2010Malpighi Hospital Bologna University Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.53.5.414"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/19.2.156"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/smrv.2002.0242"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(10)80412-4"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/17.7.624"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199908000-00017"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199912000-00002"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/22.5.667"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/6.4.303"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1983.00800220009003"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199108000-00001"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459989210700107"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016489209136818"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199705000-00011"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016480410018034"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016480410017378"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2006.06.1253","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.otohns.2006.06.1253","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2006.06.1253","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T14:13:19Z","timestamp":1760969599000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2006.06.1253"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["10.1016\/j.otohns.2006.06.1253"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2006.06.1253","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,12]]},"assertion":[{"value":"2016-05-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}