{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T09:25:19Z","timestamp":1792056319411,"version":"4.4.0"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":3424,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2007,1]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>To review the clinical manifestations and the follow\u2010up hearing results of the treatment modalities in the patients with otosyphilis.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND SETTINGS<\/jats:title><jats:p>A retrospective review between 1984 and 2000 at a university hospital. Patients who presented with cochleovestibular symptoms and were confirmed seropositive for specific treponemal tests were included. Excluded were patients older than 70, or who had other identified causes of cochleovestibular symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Subjects included 56\u00a0males and 29 females with an average age of 59.5 years (range, 40 to 70). Common presenting symptoms included hearing loss (90.6%), tinnitus (72.9%), and vertigo (52.9%). The cerebrospinal fluid analysis was positive in 5.4%. The overall respective hearing results in the short\u2010 and long\u2010term follow\u2010up were improved or stable in 93.4% and 83.3% of patients. Even though adding steroids and neurosyphilis regimens tended to improve and stabilize hearing, the results were not statistically significant among treatment modalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Further study about hearing outcomes among treatment modalities is suggested.<\/jats:p><jats:p>\u00a9 2007 American Academy of Otolaryngology\u2010Head and Neck Surgery Foundation. All rights reserved.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2006.08.026","type":"journal-article","created":{"date-parts":[[2007,1,9]],"date-time":"2007-01-09T13:55:25Z","timestamp":1168350925000},"page":"67-71","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":80,"title":["Otosyphilis: A review of 85 cases"],"prefix":"10.1002","volume":"136","author":[{"given":"Kwanchanok","family":"Yimtae","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Faculty of Medicine Khon Kaen University Khon Kaen Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somchai","family":"Srirompotong","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Faculty of Medicine Khon Kaen University Khon Kaen Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krisna","family":"Lertsukprasert","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Ramathibodi Hospital Mahidol University Khon Kaen Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198312000-00003"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348948609500308"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.12.2.187"},{"key":"e_1_2_6_5_1","first-page":"117","article-title":"Hearing and equilibrium disorders in patients with neurosyphilis.","volume":"31","author":"Schroder M","year":"1983","journal-title":"HNO"},{"key":"e_1_2_6_6_1","first-page":"247","volume-title":"Pathology of the ear","author":"Schuknecht HF","year":"1993"},{"key":"e_1_2_6_7_1","first-page":"28","article-title":"1998 guidelines for treatment of sexually transmitted diseases.","volume":"47","author":"Centers for Disease Control and Prevention.","year":"1998","journal-title":"Morbid Mortal Weekly Rep"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/21.6.1361"},{"key":"e_1_2_6_9_1","first-page":"420","article-title":"On syphilis and the ear: an otologist's veiw.","volume":"68","author":"Morrison A","year":"1992","journal-title":"Genitourinary Med"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198406000-00005"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.1979.89.8.1273"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199211000-00010"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100131147"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1985.00360030105020"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198904000-00001"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2006.08.026","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.otohns.2006.08.026","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2006.08.026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T08:50:22Z","timestamp":1760950222000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2006.08.026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["10.1016\/j.otohns.2006.08.026"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2006.08.026","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,1]]},"assertion":[{"value":"2016-05-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}