{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T02:34:42Z","timestamp":1782786882474,"version":"3.54.5"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":3393,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2007,2]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the effect of preoperative high\u2010dose systemic corticosteroids on the radiographic and endoscopic appearance of allergic fungal rhinosinusitis (AFRS) and chronic rhinosinusitis with nasal polyposis (CRSwNP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design and Setting<\/jats:title><jats:p>Eight AFRS and 10 CRSwNP patients underwent computed tomographic (CT) scans and then received preoperative 1\u00a0mg\/kg prednisone for 10\u00a0days. CT scans were repeated 1\u00a0day before surgery and compared with pretreatment scans (Lund\u2010MacKay radiologic scoring system). The endoscopic appearance was recorded intraoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The score dropped from 16 (66.4%) to 4.75\u00a0in the AFRS group and from 18.4 (23%) to 14.1\u00a0in the CRSwNP group (<jats:italic>P<\/jats:italic> = 0.0064). Intraoperatively, most sinus mucosal surfaces appeared normal in the AFRS patients but were markedly edematous in the CRSwNP patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Radiographic response of AFRS to systemic corticosteroids is significantly greater compared with CRSwNP. 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