{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T20:54:30Z","timestamp":1793048070064,"version":"4.5.0"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":3151,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2007,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The Lund\u2010Mackay score is widely used in assessment of chronic rhinosinusitis. We aimed to describe its relationship to other measures of pre\u2010 and post\u2010treatment health status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Multicenter prospective study of 1840 patients undergoing surgery for chronic rhinosinusitis in the UK.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was no absolute threshold for surgery, but patients with higher Lund\u2010Mackay scores underwent more extensive surgery. There was no correlation between Lund\u2010Mackay and SNOT\u201022 scores. The Lund\u2010Mackay increased with increasing grade of polyposis. The Lund\u2010Mackay score was associated with symptom reduction (coefficient = 0.24,\n                      <jats:italic>P<\/jats:italic>\n                      = 0.02) complication rates (odds ratio, 1.08, 95%CI 1.06 to 1.1), and revision rates (odds ratio, 1.03, 95% CI 1.001 to 1.06).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The Lund\u2010Mackay score measures a different aspect of disease to \u201csubjective\u201d symptom scores. However, it correlates well with other markers of disease severity, the nature of surgery offered, and its outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Significance<\/jats:title>\n                    <jats:p>This demonstrates the strengths and limitations of a commonly used staging system.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.otohns.2007.02.004","type":"journal-article","created":{"date-parts":[[2007,11,14]],"date-time":"2007-11-14T10:28:06Z","timestamp":1195036086000},"page":"555-561","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":452,"title":["The Lund\u2010Mackay staging system for chronic rhinosinusitis: How is it used and what does it predict?"],"prefix":"10.1002","volume":"137","author":[{"given":"Claire","family":"Hopkins","sequence":"first","affiliation":[{"name":"The Clinical Effectiveness Unit Royal College of Surgeons of England London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Browne","sequence":"additional","affiliation":[{"name":"The Clinical Effectiveness Unit Royal College of Surgeons of England London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob","family":"Slack","sequence":"additional","affiliation":[{"name":"Royal United Hospital Bath Bath UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie","family":"Lund","sequence":"additional","affiliation":[{"name":"The Royal National Throat Nose and Ear Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Brown","sequence":"additional","affiliation":[{"name":"Milton Keynes General Hospital NHS Trust Buckinghamshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,17]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"87","article-title":"European position paper on rhinosinusitis and nasal polyps","volume":"18","author":"Fokkens W","year":"2005","journal-title":"EAACI Task Force. 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