{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:45:42Z","timestamp":1761007542012,"version":"build-2065373602"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":3181,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:sec><jats:title>OBJECTIVES<\/jats:title><jats:p>The study goal was to analyze the role of planned neck dissection for squamous cell carcinoma of the base of the tongue treated with definitive radiotherapy or chemoradiation.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN, SETTING<\/jats:title><jats:p>We conducted a retrospective study of patients with squamous cell carcinoma of the base of the tongue undergoing planned neck dissection after definitive radiotherapy or chemoradiation.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Twenty\u2010two of 41 (53.7%) patients had one to six positive residual lymph nodes after receiving definitive radiotherapy or chemoradiation. Neck control rates were 92.3% and 88.3% at two and five years, respectively. Three of 22 (13.6%) patients with pathological residual nodal disease had regional or locore\u2010gional failures, compared with 1 of 19 (5.3%) patients with a pathologically complete response (<jats:italic>P<\/jats:italic> = 0.39).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>We observed a high incidence of pathologically residual lymph nodes after definitive radiotherapy or chemoradiation.<\/jats:p><\/jats:sec><jats:sec><jats:title>SIGNIFICANCE<\/jats:title><jats:p>Planned neck dissection following definitive radiotherapy or chemoradiation is highly effective in achieving regional control of squamous cell carcinoma of the base of the tongue.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2007.03.008","type":"journal-article","created":{"date-parts":[[2007,8,31]],"date-time":"2007-08-31T07:14:53Z","timestamp":1188544493000},"page":"422-427","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Planned Neck Dissection after Definitive Radiotherapy or Chemoradiation for Base of Tongue Cancers"],"prefix":"10.1002","volume":"137","author":[{"given":"Ying J.","family":"Hitchcock","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology University of Utah Salt Lake City UT"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon G.","family":"Bentz","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pramod K.","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University 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