{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:41:12Z","timestamp":1789706472366,"version":"4.0.1"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The purpose of this study was to determine the status of nasal airway and olfaction of adult subjects born with choanal atresia (CA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design and Setting<\/jats:title><jats:p>A case\u2010control study was conducted to compare the quality of nasal airway and olfaction in a group of adults born with CA to a similar group of normal subjects. Objective evaluation of nasal airway and olfaction were done respectively by acoustic rhinometry and the University of Pennsylvania Smell Identification Test (UPSIT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010six choanal atresia patients aged 16 to 36 were found in the medical records. Five bilateral and two unilateral cases were recruited for the study. An average score of 27\/40 (moderate hyposmia) was obtained by the bilateral cases compared with 37\/40 (normal) by the controls. These results were statistically significant (Wilcoxon signed rank test and sign test statistic, <jats:italic>P<\/jats:italic> = 0.03).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Using the UPSIT, the bilateral CA patients have shown, on average, a moderate loss of the sense of smell when compared with normal controls of a similar age group. Acoustic rhinometry is not a useful study for posterior nasal conditions.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2007.09.020","type":"journal-article","created":{"date-parts":[[2008,9,10]],"date-time":"2008-09-10T20:24:56Z","timestamp":1221078296000},"page":"43-49","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Choanal atresia: Long\u2010term follow\u2010up with objective evaluation of nasal airway and olfaction"],"prefix":"10.1002","volume":"138","author":[{"given":"Jacques E.","family":"Leclerc","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Laval University Quebec City Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Thomas","family":"Leclerc","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Laval University Quebec City Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,1]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(79)80513-2"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(87)90107-8"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(81)80454-4"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.155.2.3983384"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198702000-00008"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2006.01.009"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.127.11.1375"},{"key":"e_1_2_9_9_1","first-page":"139","article-title":"Choanal atresia: therapeutic management and results in a series of 58 children","volume":"124","author":"Triglia JM","year":"2003","journal-title":"Rev Laryngol Otol Rhinol (Bord)"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.05.009"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2005.05.032"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-2474"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-1970"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198911000-00011"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198402000-00004"},{"key":"e_1_2_9_16_1","first-page":"3","article-title":"Acoustic rhinometry: recommendations for technical specifications and standard operating procedures","volume":"16","author":"Hillberg O","year":"2000","journal-title":"Rhinol Suppl"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(97)00097-9"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940511401211"},{"key":"e_1_2_9_19_1","first-page":"169","article-title":"Standardisation Committee on Objective Assessment of the Nasal Airway, IRS, and ERS. 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