{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T09:06:49Z","timestamp":1792055209703,"version":"4.4.0"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2008,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine if degree of lingual tonsil hypertrophy(LTH) correlates with pharyngeal reflux.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Prospective.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with flexible laryngoscopic evidence of LTH were included. Degree of LTH was graded mild, moderate, or severe by two otolaryngologists blinded to pH study results. Threesensor pH study results were correlated to LTH grade.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nineteen patients were included (five with mild LTH, eight with moderate LTH, and six with severe LTH). Nasopharyngeal reflux (NPR) events &lt;pH4 were found in four of six severe LTH patients but no mild or moderate LTH patients (P = 0.006). All severe LTH patients had NPR events &lt;pH5, compared with only 4 of 11\u00a0mild or moderate LTH patients (P = 0.017). Atthe UES, 4 of 6 severe LTH patients had pathologic reflux, compared with 4 of 13\u00a0mild or moderate (P = 0.025). Interobserver reliability calculated by Cohen's kappa was excellent (0.92).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study shows a continuum of increasing pharyngeal reflux with higher LTH severity. Severe LTH may be a reliable physical sign of pharyngeal reflux, especially NPR.<\/jats:p><jats:p>\u00a9 2008 American Academy of Otolaryngology\u2010Head and Neck Surgery Foundation. All rights reserved.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2007.12.023","type":"journal-article","created":{"date-parts":[[2008,3,25]],"date-time":"2008-03-25T00:19:43Z","timestamp":1206404383000},"page":"473-478","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Proximal pharyngeal reflux correlates with increasing severity of lingual tonsil hypertrophy"],"prefix":"10.1002","volume":"138","author":[{"given":"John M.","family":"DelGaudio","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Emory University Atlanta GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naseri","family":"Iman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Emory University Atlanta GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin 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