{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T21:59:41Z","timestamp":1791583181947,"version":"4.3.4"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2008,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Assess paranasal sinus distribution of topical solutions following endoscopic sinus surgery (ESS) using various delivery devices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Experimental prospective study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods<\/jats:title>\n                    <jats:p>Ten cadaver sinus systems were irrigated with Gastroview before surgery, after ESS, and after medial maxillectomy. Delivery was via pressurized spray (NasaMist), neti pot (NasaFlo), and squeeze bottle (Sinus Rinse). Scans were performed before and after each delivery with a portable CT machine (Xoran xCAT), and blinded assessments were made for distribution to individual sinuses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Total sinus distribution was greater post\u2010ESS (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001). Additional distribution was gained with medial maxillectomy (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.02). Influence of delivery device on distribution was significantly higher with neti pot &gt; squeeze bottle &gt; pressurized spray (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001). Frontal sinus penetration was greatest after surgery (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>ESS greatly enhances the delivery of nasal solutions, regardless of delivery device. Pressurized spray solutions in un\u2010operated sinuses provide little more than nasal cavity distribution. Use of squeeze bottle\/neti pot post\u2010ESS offers a greatly enhanced ability to deliver solutions to the paranasal sinuses.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.otohns.2008.04.020","type":"journal-article","created":{"date-parts":[[2008,6,28]],"date-time":"2008-06-28T05:10:22Z","timestamp":1214629822000},"page":"137-142","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":190,"title":["Effects of endoscopic sinus surgery and delivery device on cadaver sinus irrigation"],"prefix":"10.1002","volume":"139","author":[{"given":"Richard J.","family":"Harvey","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Medical University of South Carolina Charleston SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John C.","family":"Goddard","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Medical University of South Carolina Charleston SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah K.","family":"Wise","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Emory University Atlanta GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney J.","family":"Schlosser","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Medical University of South Carolina Charleston SC"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,7]]},"reference":[{"issue":"3","key":"e_1_2_8_2_1","article-title":"Functional endoscopic sinus surgery for chronic rhinosinusitis.","author":"Khalil H","year":"2006","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"e_1_2_8_3_1","first-page":"3","article-title":"Biofilms and chronic rhinosinusitis: systematic review of evidence, current concepts and directions for research.","volume":"45","author":"Harvey RJ","year":"2007","journal-title":"Rhinology"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240301700303"},{"key":"e_1_2_8_5_1","first-page":"249","article-title":"Intracellular residency is frequently associated with recurrent Staphylococcus aureus rhinosinusitis.","volume":"44","author":"Plouin\u2010Gaudon I","year":"2006","journal-title":"Rhinology"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.moo.0000124938.46948.c7"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2007.06.726"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240501900601"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100117463"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100128014"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200405000-00027"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198708002-00001"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200001000-00021"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.2500\/105065897781446612"},{"key":"e_1_2_8_15_1","first-page":"131","article-title":"Comparison of radical (nasalisation) and functional ethmoidectomy in patients with severe sinonasal polyposis. 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