{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T16:39:24Z","timestamp":1761237564011,"version":"build-2065373602"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2008,9]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate the epidemiologic and microbiological characteristics of community\u2010acquired methicillin\u2010resistant <jats:italic>Staphylococcus aureus<\/jats:italic> (CA\u2010MRSA) and hospital\u2010acquired methicillin\u2010resistant <jats:italic>Staphylococcus aureus<\/jats:italic> (HA\u2010MRSA) infections in the otorrhea of chronic suppurative otitis media (COM) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Retrospective study of patients with newly identified MRSA infections from January 1998 through December 2006. A total of 2773 patients with a diagnosis of COM were included in this study. An antibiotic sensitivity test was performed for each isolate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of MRSA in COM was 4.9 percent (137 of 2773 patients). The proportion of CA\u2010MRSA rose from 0.7 percent in 1998 to 11.4 percent in 2006. However, the proportion of HA\u2010MRSA did not change significantly, from 0.7 percent in 1999 to 1.3 percent in 2006. All of the CA\u2010MRSA strains identified in our study were susceptible to trimethoprim\/sulfamethoxazole (TMP\/SMX). Rifampin susceptibility was also noted in 90 percent of the cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CA\u2010MRSA infections have risen dramatically in the past decade. CA\u2010MRSA and HA\u2010MRSA in COM differed in both clinical and microbiological aspects. \u00a9 2008 American Academy of Otolaryngology\u2010Head and Neck Surgery Foundation. All rights reserved.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2008.06.025","type":"journal-article","created":{"date-parts":[[2008,8,23]],"date-time":"2008-08-23T07:18:53Z","timestamp":1219475933000},"page":"395-398","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["The changes of MRSA infections in chronic suppurative otitis media"],"prefix":"10.1002","volume":"139","author":[{"given":"Moo Kyun","family":"Park","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Korea University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung Ho","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Korea University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hee Joon","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Korea University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong\u2010Soo","family":"Woo","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Korea University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heung\u2010Man","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Korea University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hak Hyun","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Korea University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soon Jae","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Korea University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Won","family":"Chae","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Korea University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5219.124-a"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199808203390806"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-97-3-309"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268800029496"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/427701"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa042859"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.279.8.593"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.22.2976"},{"volume-title":"Performance standards for antimicrobial susceptibility testing; 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