{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:37:24Z","timestamp":1761007044235,"version":"build-2065373602"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine whether there is a difference in the pneumatization of temporal bones with otosclerosis versus normal temporal bones.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study of 46 ears from 24 adult patients with otosclerosis and 64 ears from 47 adult patients in a control group. The study group included temporal bone CT scans available from patients with otosclerosis. The control group consisted of patients who had temporal bone CTs for reasons likely unrelated to a history of middle ear disease. Data were obtained with a virtual reality system that allows three\u2010dimensional manipulation and analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The temporal bone pneumatization for the otosclerosis group was 4.82 \u00b1 2.27\u00a0cm<jats:sup>3<\/jats:sup> vs 6.06 \u00b1 2.71\u00a0cm<jats:sup>3<\/jats:sup> for the control group. Two\u2010sample <jats:italic>t<\/jats:italic> test analysis revealed no statistical significance (<jats:italic>P<\/jats:italic> = 0.059) between pneumatization in the control vs otosclerosis groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There is no difference in temporal bone pneumatization between patients with otosclerosis and a control population. Therefore, temporal bone pneumatization by itself is not an adequate explanation for the apparent protective effect of otosclerosis against otitis media.<\/jats:p><jats:p>\u00a9 2008 American Academy of Otolaryngology\u2010Head and Neck Surgery Foundation. All rights reserved.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2008.09.004","type":"journal-article","created":{"date-parts":[[2008,11,28]],"date-time":"2008-11-28T05:11:24Z","timestamp":1227849084000},"page":"850-853","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Temporal bone Pneumatization in Otosclerosis"],"prefix":"10.1002","volume":"139","author":[{"given":"Daniel T.","family":"Ganc","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery New Jersey Medical School \u2010 University of Medicine and Dentistry of New Jersey (UMDNJ) Newark NJ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert W.","family":"Jyung","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery New Jersey Medical School \u2010 University of Medicine and Dentistry of New Jersey (UMDNJ) Newark NJ"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200311000-00007"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1992.tb01004.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(81)90008-2"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016489009124811"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949710600107"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348948909800611"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016489950180991"},{"issue":"4","key":"e_1_2_8_9_1","first-page":"319","article-title":"Mastoid pneumatization in otosclerosis","volume":"49","author":"Pyd M","year":"1995","journal-title":"Otolaryngol Pol"},{"volume-title":"Statistical power analysis for the behavioral sciences","year":"1988","author":"Cohen J","key":"e_1_2_8_10_1"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940111000516"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2007.04.019"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.145.3.473"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348946707600207"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.2007.01475.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000150702.28451.35"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000191466.09210.9a"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2008.09.004","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.otohns.2008.09.004","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2008.09.004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T11:33:14Z","timestamp":1760959994000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2008.09.004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["10.1016\/j.otohns.2008.09.004"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2008.09.004","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[2008,12]]},"assertion":[{"value":"2008-06-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-09-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-12-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}