{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T10:51:21Z","timestamp":1779879081722,"version":"3.53.1"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2009,8,1]],"date-time":"2009-08-01T00:00:00Z","timestamp":1249084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2009,8]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>The purpose of this study was to evaluate changes in airway infantile hemangioma treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN<\/jats:title><jats:p>Retrospective.<\/jats:p><\/jats:sec><jats:sec><jats:title>SUBJECTS<\/jats:title><jats:p>Airway hemangioma patients, tertiary pediatric hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>Data collected included age at diagnosis, evaluation methods, hospitalizations, airway size, and interventions. Patients were divided into group A (1981\u20131993) and group B (1994\u20132005) and were analyzed using descriptive statistics, the Fisher exact test, and the Student <jats:italic>t<\/jats:italic> test.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Thirty\u2010two subjects were identified. Nasopharyngoscopy was used more in group B (11\/16 [69%]) than group A (4\/16 [25%], <jats:italic>P<\/jats:italic> = 0.032). CT angiography (3\/16 [19%]) and laryngeal distractors (11\/16 [69%]) were only used in group B; these techniques showed airway hemangiomas to be \u201ctransglottic,\u201d not just \u201csubglottic.\u201d Intralesional steroids alone (3\/16 [19%]) and primary hemangioma excision (2\/16 [13%]) were new treatments used in group B. Frequent direct laryngoscopies (&gt;six) correlated with tracheotomy (5\/32 [16%], <jats:italic>P<\/jats:italic> = 0.015). Presenting age (&lt;2\u00a0months) impacted treatment more than airway hemangioma size.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>New methods of airway infantile hemangioma assessment changed our concept of airway hemangiomas and their primary treatment.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2009.04.013","type":"journal-article","created":{"date-parts":[[2009,7,29]],"date-time":"2009-07-29T09:17:07Z","timestamp":1248859027000},"page":"207-212","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Emerging Concepts in Airway Infantile Hemangioma Assessment and Management"],"prefix":"10.1002","volume":"141","author":[{"given":"Jonathan A.","family":"Perkins","sequence":"first","affiliation":[{"name":"Division of Pediatric Otolaryngology Department of Otolaryngology\u2010Head and Neck Surgery Seattle Children's Hospital Seattle 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