{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T19:56:23Z","timestamp":1792439783901,"version":"4.5.0"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:sec><jats:title>OBJECTIVES<\/jats:title><jats:p>OK\u2010432 has been widely used to treat lymphangioma and ranula; however, there are few studies for its use in treatment of branchial cleft cyst (BCC). We conducted this study to evaluate the effectiveness of sclerotherapy using OK\u2010432\u00a0in treatment of BCC.<\/jats:p><\/jats:sec><jats:sec><jats:title>STUDY DESIGN AND SETTING<\/jats:title><jats:p>Case series with planned data collection.<\/jats:p><\/jats:sec><jats:sec><jats:title>SUBJECTS AND METHODS<\/jats:title><jats:p>From 2004 to 2007, we treated 23 patients with BCC using OK\u2010432 sclerotherapy. Of these 23 patients, 18 had unilocular cysts and five had multilocular cysts. The sizes of the BCCs were measured and compared before and after treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Of the 23 cases, 14 (60.8%) showed complete regression; all of these were unilocular cysts. Of the remaining individuals with unilocular cysts, only one patient failed to show any response. This individual subsequently underwent surgical excision. A total of five patients with multilocular cysts showed no or partial response and subsequently underwent surgical excision. Minor adverse effects including fever and local pain were reported by 13 (56.5%) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>These results suggest that sclerotherapy using OK\u2010432 is an effective and safe treatment modality for BCC, especially for unilocular cysts. Sclerosing of unilocular BCC with OK\u2010432 should therefore be considered before surgical excision.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2009.05.022","type":"journal-article","created":{"date-parts":[[2009,8,26]],"date-time":"2009-08-26T06:13:53Z","timestamp":1251267233000},"page":"329-334","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Sclerotherapy of Branchial Cleft Cysts Using OK\u2010432"],"prefix":"10.1002","volume":"141","author":[{"given":"Myung\u2010Gu","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Masan Samsung Hospital Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"No\u2010Hee","family":"Lee","sequence":"additional","affiliation":[{"name":"Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Seoul 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