{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:27:45Z","timestamp":1761006465115,"version":"build-2065373602"},"reference-count":8,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2010,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To analyze the long\u2010term results and the complications related to an expanded series of maxillary removal and reinsertion (MRRI) with 18\u2010year surgical experience.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case series with chart review of the MRRI patients in the last 18 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>The Ohio State University Comprehensive Cancer Center, James Cancer Hospital and Solove Research Institute.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Seventy\u2010eight patients who underwent MRRI from February 1990 through February 2007. The median age was 51 years (range 11\u201077 yrs). Sixty\u2010two (80%) patients had malignant lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>MRRI has been successfully completed in all 78 patients, with no intraoperative mortality. The most commonly encountered malignant neoplasm was squamous cell cancer (40.3%), followed by esthesioneuroblastoma (24.1%), adenoid cystic cancer (8%), and other neoplasms (27.4%). The most commonly encountered postoperative complication was diplopia, which has persisted in five (6.4%) patients in the short\u2010term and in three (4%) patients in the long\u2010term follow\u2010up. Nasal asymmetry was the most common long\u2010term complication (17.9%), followed by plate\u2010associated problems (10.2%) and midface asymmetry (10.2%). Overall five\u2010year survival for the patients with squamous cell carcinoma was 62 percent.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MRRI is a favorable surgical technique for the treatment of anterior cranial base (ACB) tumors in adults and even in children. It improves operative morbidity by preserving both function and form of the maxillary region and gives excellent exposure to ACB.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.otohns.2009.11.027","type":"journal-article","created":{"date-parts":[[2010,1,25]],"date-time":"2010-01-25T02:04:45Z","timestamp":1264385085000},"page":"322-326","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Maxillary removal and reinsertion: A favorable approach for extensive anterior cranial base tumors"],"prefix":"10.1002","volume":"142","author":[{"given":"Enver","family":"Ozer","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Comprehensive Cancer Center the Ohio State University Columbus OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumit","family":"Bapna","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Comprehensive Cancer Center the Ohio State University Columbus OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Agrawal","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Comprehensive Cancer Center the Ohio State University Columbus OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David E.","family":"Schuller","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Comprehensive Cancer Center the Ohio State University Columbus OH"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11630"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-199501000-00017"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.10250"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199202000-00017"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.124.2.149"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.128.1.29"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198410000-00018"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.05.029"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2009.11.027","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.otohns.2009.11.027","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.otohns.2009.11.027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T09:03:21Z","timestamp":1760951001000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.otohns.2009.11.027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["10.1016\/j.otohns.2009.11.027"],"URL":"https:\/\/doi.org\/10.1016\/j.otohns.2009.11.027","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"type":"print","value":"0194-5998"},{"type":"electronic","value":"1097-6817"}],"subject":[],"published":{"date-parts":[[2010,3]]},"assertion":[{"value":"2009-08-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-11-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-03-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}