{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T17:59:15Z","timestamp":1778867955151,"version":"3.51.4"},"reference-count":7,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Otorrinolaringol\u00f3gica Espa\u00f1ola"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1016\/j.otorri.2009.10.008","type":"journal-article","created":{"date-parts":[[2010,2,12]],"date-time":"2010-02-12T04:27:19Z","timestamp":1265948839000},"page":"452-454","source":"Crossref","is-referenced-by-count":3,"title":["Respuesta a quimioterapia metron\u00f3mica en un carcinoma adenoide qu\u00edstico metast\u00e1sico de par\u00f3tida"],"prefix":"10.1016","volume":"61","author":[{"given":"Laura","family":"Visa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Caballero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan J.","family":"Grau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.otorri.2009.10.008_bib1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s12094-007-0018-3","article-title":"Metronomic chemotherapy: an antiangiogenic scheduling","volume":"9","author":"Laquente","year":"2007","journal-title":"Clin Transl Oncol"},{"key":"10.1016\/j.otorri.2009.10.008_bib2","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/jnci\/92.3.205","article-title":"New guidelines to evaluate the response to treatment in solid tumors","volume":"92","author":"Therase","year":"2000","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.otorri.2009.10.008_bib3","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/hed.20327","article-title":"Phase II trial of taxol in salivary gland malignancies (E1394): a trial of the Eastern Cooperative Oncology Group","volume":"28","author":"Gilbert","year":"2006","journal-title":"Head Neck"},{"key":"10.1016\/j.otorri.2009.10.008_bib4","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1001\/archotol.133.11.1143","article-title":"M. Serum vascular endothelial growth factor as prognostic factor in metronomic (weekly) paclitaxel treatment for advanced head and neck cancer","volume":"133","author":"Caballero","year":"2007","journal-title":"Arch Otolaryngol"},{"key":"10.1016\/j.otorri.2009.10.008_bib5","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1097\/00001813-200301000-00003","article-title":"Paclitaxel at ultra low concentrations inhibits angiogenesis without affecting cellular microtubule assembly","volume":"14","author":"Wang","year":"2003","journal-title":"Anticancer Drugs"},{"key":"10.1016\/j.otorri.2009.10.008_bib6","first-page":"427","article-title":"The antiangiogenic scheduling of lower dose cancer chemotherapy","volume":"7","author":"Gately","year":"2001","journal-title":"Cancer J"},{"key":"10.1016\/j.otorri.2009.10.008_bib7","first-page":"1878","article-title":"Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer","volume":"60","author":"Browder","year":"2000","journal-title":"Cancer Res"}],"container-title":["Acta Otorrinolaringol\u00f3gica Espa\u00f1ola"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001651909001435?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001651909001435?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,13]],"date-time":"2018-12-13T03:53:14Z","timestamp":1544673194000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0001651909001435"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":7,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["S0001651909001435"],"URL":"https:\/\/doi.org\/10.1016\/j.otorri.2009.10.008","relation":{},"ISSN":["0001-6519"],"issn-type":[{"value":"0001-6519","type":"print"}],"subject":[],"published":{"date-parts":[[2010,11]]}}}