{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:47:04Z","timestamp":1761896824412},"reference-count":15,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Otorrinolaringol\u00f3gica Espa\u00f1ola"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.otorri.2018.06.001","type":"journal-article","created":{"date-parts":[[2018,8,11]],"date-time":"2018-08-11T12:12:50Z","timestamp":1533989570000},"page":"229-234","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["l-Thyroxine does not prevent immunemediated sensorineural hearing loss in autoimmune thyroid diseases"],"prefix":"10.1016","volume":"70","author":[{"given":"Antonio","family":"Rodr\u00edguez-Valiente","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d3scar","family":"\u00c1lvarez-Montero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"G\u00f3rriz-Gil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Ram\u00f3n","family":"Garc\u00eda-Berrocal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.otorri.2018.06.001_bib0080","series-title":"Werner and Ingbar's the thyroid: a fundamental and clinical text","first-page":"p398","article-title":"The epidemiology of thyroid diseases","author":"Vanderpump","year":"2005"},{"key":"10.1016\/j.otorri.2018.06.001_bib0085","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1258\/002221503770716188","article-title":"Sudden presentation of immune-mediated inner ear disease: characterization and acceptance of a cochleovestibular dysfunction","volume":"117","author":"Garc\u00eda-Berrocal","year":"2003","journal-title":"J Laryngol Otol"},{"key":"10.1016\/j.otorri.2018.06.001_bib0090","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/BF02993744","article-title":"Hearing profile in hypothyroidism","volume":"54","author":"Malik","year":"2002","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.otorri.2018.06.001_bib0095","first-page":"30","article-title":"The hearing system under thyroid hypofunction","author":"Khechinaschvili","year":"2007","journal-title":"Georgian Med News"},{"key":"10.1016\/j.otorri.2018.06.001_bib0100","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/s12020-011-9515-9","article-title":"Evaluation of hearing loss in patients with Graves\u2019 disease","volume":"41","author":"Berker","year":"2012","journal-title":"Endocrine"},{"key":"10.1016\/j.otorri.2018.06.001_bib0105","doi-asserted-by":"crossref","first-page":"138","DOI":"10.4103\/0971-7749.155310","article-title":"Is sensorineural hearing loss related with thyroid metabolism disorders","volume":"21","author":"Karakus","year":"2015","journal-title":"Indian J Otol"},{"key":"10.1016\/j.otorri.2018.06.001_bib0110","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1177\/000348940411300512","article-title":"Controversies and criticisms in experimental autoimmune labyrinthitis designs","volume":"11","author":"Garc\u00eda-Berrocal","year":"2004","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"10.1016\/j.otorri.2018.06.001_bib0115","doi-asserted-by":"crossref","first-page":"222","DOI":"10.3109\/08916934.2012.751981","article-title":"Lower proportions of CD4+ CD25high and CD4+ Foxp3+, but not CD4+ CD25+ CD127low Foxp3+ T cell levels in children with autoimmune thyroid diseases","volume":"46","author":"Bossowski","year":"2013","journal-title":"Autoimmunity"},{"key":"10.1016\/j.otorri.2018.06.001_bib0120","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1001\/archotol.1997.01900070056009","article-title":"Deficiency of naive T cells in patients with sudden deafness","volume":"123","author":"Garc\u00eda-Berrocal","year":"1997","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.otorri.2018.06.001_bib0125","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1177\/000348940211101107","article-title":"Sudden sensorineural hearing loss: supporting the immunologic theory","volume":"111","author":"Garc\u00eda Berrocal","year":"2002","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"10.1016\/j.otorri.2018.06.001_bib0130","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/nri3464","article-title":"The plasticity and stability of regulatory T cells","volume":"13","author":"Sakaguchi","year":"2013","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.otorri.2018.06.001_bib0135","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1007\/s12020-015-0759-7","article-title":"T regulatory (Treg) and T helper 17 (Th17) lymphocytes in thyroid autoimmunity","volume":"52","author":"Gonz\u00e1lez-Amaro","year":"2016","journal-title":"Endocrine"},{"key":"10.1016\/j.otorri.2018.06.001_bib0140","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.mehy.2006.02.044","article-title":"Central role of supporting cells in cochlear homeostasis and pathology","volume":"67","author":"Ram\u00edrez-Camacho","year":"2006","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.otorri.2018.06.001_bib0145","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.rx.2016.10.006","article-title":"Diagnosis of endolymphatic hydrops by means of 3T magnetic resonance imaging after intratympanic administration of gadolinium","volume":"59","author":"Tu\u00f1\u00f3n G\u00f3mez","year":"2017","journal-title":"Radiologia"},{"key":"10.1016\/j.otorri.2018.06.001_bib0150","doi-asserted-by":"crossref","first-page":"91","DOI":"10.5662\/wjm.v4.i2.91","article-title":"New prospects in the diagnosis and treatment of immune-mediated inner ear disease","volume":"4","author":"Lobo","year":"2014","journal-title":"World J Methodol"}],"container-title":["Acta Otorrinolaringol\u00f3gica Espa\u00f1ola"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001651918301237?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001651918301237?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T02:32:17Z","timestamp":1661740337000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0001651918301237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["S0001651918301237"],"URL":"https:\/\/doi.org\/10.1016\/j.otorri.2018.06.001","relation":{},"ISSN":["0001-6519"],"issn-type":[{"value":"0001-6519","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"l-Thyroxine does not prevent immunemediated sensorineural hearing loss in autoimmune thyroid diseases","name":"articletitle","label":"Article Title"},{"value":"Acta Otorrinolaringol\u00f3gica Espa\u00f1ola","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.otorri.2018.06.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Sociedad Espa\u00f1ola de Otorrinolaringolog\u00eda y Cirug\u00eda de Cabeza y Cuello. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}