{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T19:06:24Z","timestamp":1793473584015,"version":"4.5.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedics & Traumatology: Surgery & Research"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.otsr.2021.102877","type":"journal-article","created":{"date-parts":[[2021,2,27]],"date-time":"2021-02-27T11:32:22Z","timestamp":1614425542000},"page":"102877","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Risk factors for complications after primary intramedullary nailing to treat tibial shaft fractures: A cohort study of 184 consecutive patients"],"prefix":"10.1016","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6033-9485","authenticated-orcid":false,"given":"Paul-Henri","family":"Bauwens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthieu","family":"Malatray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaspard","family":"Fournier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Rongieras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Bertani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.otsr.2021.102877_bib0145","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.injury.2006.04.130","article-title":"Epidemiology of adult fractures: a review","volume":"37","author":"Court-Brown","year":"2006","journal-title":"Injury"},{"key":"10.1016\/j.otsr.2021.102877_bib0150","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1016\/j.injury.2011.10.015","article-title":"Prevalence of complications of open tibial shaft fractures stratified as per the Gustilo\u2013Anderson classification","volume":"42","author":"Papakostidis","year":"2011","journal-title":"Injury"},{"key":"10.1016\/j.otsr.2021.102877_bib0155","doi-asserted-by":"crossref","first-page":"e332","DOI":"10.3928\/01477447-20140401-52","article-title":"A meta-analysis of reamed versus unreamed intramedullary nailing for the treatment of closed tibial fractures","volume":"37","author":"Xia","year":"2014","journal-title":"Orthopedics"},{"key":"10.1016\/j.otsr.2021.102877_bib0160","first-page":"CD008241","article-title":"Intramedullary nailing for tibial shaft fractures in adults","volume":"1","author":"Duan","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.otsr.2021.102877_bib0165","doi-asserted-by":"crossref","first-page":"S74","DOI":"10.1016\/j.injury.2006.04.012","article-title":"Antibiotics in trauma and orthopedic surgery \u2013 a primer of evidence-based recommendations","volume":"37","author":"Jaeger","year":"2006","journal-title":"Injury"},{"key":"10.1016\/j.otsr.2021.102877_bib0170","series-title":"Antibioprophylaxie en chirurgie et m\u00e9decine interventionnelle (patients adultes) \u2013 La SFAR","author":"Admin_sfar.","year":"2015"},{"key":"10.1016\/j.otsr.2021.102877_bib0175","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0246-0521(07)41018-X","article-title":"Fractures ouvertes de jambe","volume":"2","author":"Dubrana","year":"2007","journal-title":"EMC Appar Locomoteur"},{"key":"10.1016\/j.otsr.2021.102877_bib0180","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1097\/00003086-199908000-00024","article-title":"Effect of smoking on tibial shaft fracture healing","volume":"365","author":"Schmitz","year":"1999","journal-title":"Clin Orthop"},{"key":"10.1016\/j.otsr.2021.102877_bib0185","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1016\/j.injury.2011.05.011","article-title":"Cigarette smoking influences the clinical and occupational outcome of patients with tibial shaft fractures","volume":"42","author":"Moghaddam","year":"2011","journal-title":"Injury"},{"key":"10.1016\/j.otsr.2021.102877_bib0190","first-page":"111","article-title":"The effects of smoking on fracture healing","volume":"8","author":"Sloan","year":"2010","journal-title":"Surg J R Coll Surg Edinb Irel"},{"key":"10.1016\/j.otsr.2021.102877_bib0195","doi-asserted-by":"crossref","first-page":"674","DOI":"10.2106\/JBJS.M.00081","article-title":"Cigarette smoking increases complications following fracture: a systematic review","volume":"96","author":"Scolaro","year":"2014","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.otsr.2021.102877_bib0200","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0020-1383(00)00121-2","article-title":"Cigarette smoking and open tibial fractures","volume":"32","author":"Adams","year":"2001","journal-title":"Injury"},{"key":"10.1016\/j.otsr.2021.102877_bib0205","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/j.injury.2010.03.014","article-title":"Cigarette smoking decreases TGF-b1 serum concentrations after long bone fracture","volume":"41","author":"Moghaddam","year":"2010","journal-title":"Injury"},{"key":"10.1016\/j.otsr.2021.102877_bib0210","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1302\/0301-620X.83B1.0830062","article-title":"Treatment of open fractures of the shaft of the tibia","volume":"83","author":"Bhandari","year":"2001","journal-title":"J Bone Joint Surg Br"},{"key":"10.1016\/j.otsr.2021.102877_bib0215","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1002\/jor.1100150414","article-title":"Influence of size and stability of the osteotomy gap on the success of fracture healing","volume":"15","author":"Claes","year":"1997","journal-title":"J Orthop Res"},{"key":"10.1016\/j.otsr.2021.102877_bib0220","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.otsr.2019.04.020","article-title":"Intramedullary nailing for adult open tibial shaft fracture. An 85-case series","volume":"105","author":"Laigle","year":"2019","journal-title":"Orthop Traumatol Surg Res"},{"key":"10.1016\/j.otsr.2021.102877_bib0225","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.otsr.2019.01.015","article-title":"Predictors of mechanical complications after intramedullary nailing of tibial fractures","volume":"105","author":"Manon","year":"2019","journal-title":"Orthop Traumatol Surg Res"},{"key":"10.1016\/j.otsr.2021.102877_bib0230","first-page":"432","article-title":"Residual interfragmentary gap after intramedullary nailing of fragility fractures of the humeral diaphysis: short and midterm term results","volume":"90","author":"Ferrara","year":"2019","journal-title":"Acta Biomed"},{"key":"10.1016\/j.otsr.2021.102877_bib0235","doi-asserted-by":"crossref","first-page":"S40","DOI":"10.1016\/S0020-1383(17)30793-3","article-title":"Influence of gap size, screw configuration, and nail materials in the stability of anterograde reamed intramedullary nail in femoral transverse fractures","volume":"48","author":"Gabarre","year":"2017","journal-title":"Injury"},{"key":"10.1016\/j.otsr.2021.102877_bib0240","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1016\/j.injury.2017.03.038","article-title":"Comparing hospital outcomes between open and closed tibia fractures treated with intramedullary fixation","volume":"48","author":"Smith","year":"2017","journal-title":"Injury"},{"key":"10.1016\/j.otsr.2021.102877_bib0245","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.otsr.2016.09.019","article-title":"Does weight-bearing assignment after intramedullary nail placement alter healing of tibial shaft fractures?","volume":"103","author":"Greenhill","year":"2017","journal-title":"Orthop Traumatol Surg Res"},{"key":"10.1016\/j.otsr.2021.102877_bib0250","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1007\/s00590-018-2190-2","article-title":"Delay in weight bearing in surgically treated tibial shaft fractures is associated with impaired healing: a cohort analysis of 166 tibial fractures","volume":"28","author":"Houben","year":"2018","journal-title":"Eur J Orthop Surg Traumatol"},{"key":"10.1016\/j.otsr.2021.102877_bib0255","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/1471-2474-9-91","article-title":"Study to prospectively evaluate reamed intramedually nails in patients with tibial fractures (S.P.R.I.N.T.): study rationale and design","volume":"9","author":"SPRINT Investigators.","year":"2008","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.otsr.2021.102877_bib0260","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/00003086-199506000-00003","article-title":"Factors influencing the outcome of closed tibial fractures treated with functional bracing","volume":"315","author":"Sarmiento","year":"1995","journal-title":"Clin Orthop"},{"key":"10.1016\/j.otsr.2021.102877_bib0265","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.2106\/00004623-199408000-00006","article-title":"Interobserver agreement in the classification of open fractures of the tibia. The results of a survey of two hundred and forty-five orthopaedic surgeons","volume":"76","author":"Brumback","year":"1994","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.otsr.2021.102877_bib0270","doi-asserted-by":"crossref","first-page":"653","DOI":"10.3109\/17453674.2012.747054","article-title":"Patient-related risk factors for fracture-healing complications in the United Kingdom general practice research database","volume":"83","author":"Hernandez","year":"2012","journal-title":"Acta Orthop"},{"key":"10.1016\/j.otsr.2021.102877_bib0275","doi-asserted-by":"crossref","first-page":"410","DOI":"10.4103\/0019-5413.43385","article-title":"Immediate versus delayed intramedullary nailing for open fractures of the tibial shaft: a multivariate analysis of factors affecting deep infection and fracture healing","volume":"42","author":"Yokoyama","year":"2008","journal-title":"Indian J Orthop"},{"key":"10.1016\/j.otsr.2021.102877_bib0280","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/1471-2474-14-103","article-title":"Predictors of non-union and reoperation in patients with fractures of the tibia: an observational study","volume":"14","author":"Fong","year":"2013","journal-title":"BMC Musculoskelet Disord"}],"container-title":["Orthopaedics & Traumatology: Surgery & Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S187705682100089X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S187705682100089X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T03:45:41Z","timestamp":1761795941000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S187705682100089X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["S187705682100089X"],"URL":"https:\/\/doi.org\/10.1016\/j.otsr.2021.102877","relation":{},"ISSN":["1877-0568"],"issn-type":[{"value":"1877-0568","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk factors for complications after primary intramedullary nailing to treat tibial shaft fractures: A cohort study of 184 consecutive patients","name":"articletitle","label":"Article Title"},{"value":"Orthopaedics & Traumatology: Surgery & Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.otsr.2021.102877","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}],"article-number":"102877"}}