{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T21:05:17Z","timestamp":1770843917007,"version":"3.50.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Orthopaedics &amp; Traumatology: Surgery &amp; Research"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.otsr.2025.104437","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T04:43:42Z","timestamp":1758602622000},"page":"104437","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"S","title":["Pathologies of the cervical spine in skeletal syndromes and dysplasias"],"prefix":"10.1016","volume":"112","author":[{"given":"Rapha\u00ebl","family":"Vialle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.otsr.2025.104437_bib0005","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1007\/s002470050156","article-title":"The cervical spine in the skeletal dysplasias and associated disorders","volume":"27","author":"Lachman","year":"1997","journal-title":"Pediatr Radiol"},{"issue":"12","key":"10.1016\/j.otsr.2025.104437_bib0010","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1038\/gim.2018.50","article-title":"Expanding the phenome and variome of skeletal dysplasia","volume":"20","author":"Maddirevula","year":"2018","journal-title":"Genet Med"},{"issue":"10","key":"10.1016\/j.otsr.2025.104437_bib0015","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1111\/pan.13481","article-title":"Cervical instability in patients with trisomy 21: the eternal gamble","volume":"28","author":"Bertolizio","year":"2018","journal-title":"Paediatr Anaesth"},{"issue":"6","key":"10.1016\/j.otsr.2025.104437_bib0020","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/j.jspd.2019.01.012","article-title":"An updated algorithm for radiographic screening of upper cervical instability in patients with Down syndrome","volume":"7","author":"Bouchard","year":"2019","journal-title":"Spine Deform"},{"issue":"8","key":"10.1016\/j.otsr.2025.104437_bib0025","doi-asserted-by":"crossref","first-page":"e646","DOI":"10.1097\/BPO.0000000000001884","article-title":"Repeat pediatric trisomy 21 radiographic exam: does atlantoaxial instability develop over time?","volume":"41","author":"Bauer","year":"2021","journal-title":"J Pediatr Orthop"},{"issue":"42","key":"10.1016\/j.otsr.2025.104437_bib0030","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000040113","article-title":"Risk and clinical characteristics of spinal cord compression across different mucopolysaccharidosis types: a retrospective cohort study","volume":"103","author":"Kim","year":"2024","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.otsr.2025.104437_bib0035","doi-asserted-by":"crossref","first-page":"e157","DOI":"10.1016\/j.wneu.2022.10.100","article-title":"A review of spinal lesions in neurofibromatosis type 1 in a large neurofibromatosis type 1 center","volume":"169","author":"Sial","year":"2023","journal-title":"World Neurosurg"},{"key":"10.1016\/j.otsr.2025.104437_bib0040","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1186\/s12891-021-04864-8","article-title":"Halo traction combined with posterior-only approach correction for cervical kyphosis with Neurofibromatosis-1: minimum 2 years follow-up","volume":"22","author":"Zhang","year":"2021","journal-title":"BMC Musculoskelet Disord"},{"issue":"2","key":"10.1016\/j.otsr.2025.104437_bib0045","article-title":"Aortic size distribution among normal, hypertension, bicuspid, and Marfan populations","volume":"1","author":"Wu","year":"2023","journal-title":"Eur Heart J Imaging Methods Pract"},{"issue":"9","key":"10.1016\/j.otsr.2025.104437_bib0050","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1097\/00007632-199705010-00010","article-title":"The cervical spine in Marfan syndrome","volume":"22","author":"Hobbs","year":"1997","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.1016\/j.otsr.2025.104437_bib0055","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s13023-020-1310-3","article-title":"Neurofibromatosis 1 French national guidelines based on an extensive literature review since 1966","volume":"15","author":"Bergqvist","year":"2020","journal-title":"Orphanet J Rare Dis"},{"issue":"7","key":"10.1016\/j.otsr.2025.104437_bib0060","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1136\/jmg.2009.072785","article-title":"The revised Ghent nosology for the Marfan syndrome","volume":"47","author":"Loeys","year":"2010","journal-title":"J Med Genet"},{"issue":"1","key":"10.1016\/j.otsr.2025.104437_bib0065","doi-asserted-by":"crossref","first-page":"e4","DOI":"10.1097\/BPO.0000000000000656","article-title":"Spontaneous fatal intraoperative rupture of great vessel during growing rod lengthening: do children with Ehlers-Danlos syndrome require the availability of vascular expertise? A case report and review of the literature","volume":"37","author":"Working","year":"2017","journal-title":"J Pediatr Orthop"},{"issue":"1","key":"10.1016\/j.otsr.2025.104437_bib0070","doi-asserted-by":"crossref","first-page":"75","DOI":"10.3390\/diagnostics13010075","article-title":"Mucopolysaccharidosis: what pediatric rheumatologists and orthopedics need to know","volume":"13","author":"Costi","year":"2022","journal-title":"Diagnostics (Basel)"},{"key":"10.1016\/j.otsr.2025.104437_bib0075","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1186\/s13023-022-02593-2","article-title":"Understanding the challenges, unmet needs, and expectations of mucopolysaccharidoses I, II and VI patients and their caregivers in France: a survey study","volume":"17","author":"Guffon","year":"2022","journal-title":"Orphanet J Rare Dis"},{"issue":"1123","key":"10.1016\/j.otsr.2025.104437_bib0080","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20210223","article-title":"Pictorial review: imaging of the spinal manifestations of achondroplasia","volume":"94","author":"Khalid","year":"2021","journal-title":"Br J Radiol"},{"issue":"1","key":"10.1016\/j.otsr.2025.104437_bib0085","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/s00381-025-06777-6","article-title":"Flexion-extension cervical MRI imaging in pediatric patients with achondroplasia unsupervised by neurosurgery or radiology, is it safe?","volume":"41","author":"Masarwy","year":"2025","journal-title":"Childs Nerv Syst"},{"issue":"4","key":"10.1016\/j.otsr.2025.104437_bib0090","doi-asserted-by":"crossref","first-page":"378","DOI":"10.3171\/2017.5.PEDS16554","article-title":"Surgical management of cervical spine deformity in chondrodysplasia punctata","volume":"20","author":"Morota","year":"2017","journal-title":"J Neurosurg Pediatr"},{"issue":"7","key":"10.1016\/j.otsr.2025.104437_bib0095","article-title":"Larsen syndrome and associated spinal deformities","volume":"15","author":"Siafaka","year":"2023","journal-title":"Cureus"},{"issue":"8","key":"10.1016\/j.otsr.2025.104437_bib0100","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1002\/ajmg.a.32191","article-title":"Revisiting metatropic dysplasia: presentation of a series of 19 novel patients and review of the literature","volume":"146A","author":"Genevi\u00e8ve","year":"2008","journal-title":"Am J Med Genet A"},{"issue":"2","key":"10.1016\/j.otsr.2025.104437_bib0105","doi-asserted-by":"crossref","DOI":"10.2106\/JBJS.RVW.21.00166","article-title":"Klippel-Feil syndrome: clinical presentation and management","volume":"10","author":"Jae-Min Park","year":"2022","journal-title":"JBJS Rev"},{"issue":"3","key":"10.1016\/j.otsr.2025.104437_bib0110","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1007\/s43390-023-00641-w","article-title":"Rate and risk factors for pediatric cervical spine fusion pseudarthrosis: opportunity for improvement","volume":"11","author":"Compton","year":"2023","journal-title":"Spine Deform"},{"key":"10.1016\/j.otsr.2025.104437_bib0115","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.wneu.2017.01.048","article-title":"Congenital cervical fusion as a risk factor for development of degenerative cervical myelopathy","volume":"100","author":"Nouri","year":"2017","journal-title":"World Neurosurg"},{"key":"10.1016\/j.otsr.2025.104437_bib0120","article-title":"Cranio-cervical decompression associated with non-instrumented occipito-C2 fusion in children with mucopolysaccharidoses: report of twenty-one cases","volume":"12","author":"Zairi","year":"2022","journal-title":"N Am Spine Soc J"},{"issue":"21","key":"10.1016\/j.otsr.2025.104437_bib0125","doi-asserted-by":"crossref","first-page":"e95","DOI":"10.2106\/JBJS.16.00096","article-title":"Outcomes of spinal fusion for cervical kyphosis in children with neurofibromatosis","volume":"98","author":"Helenius","year":"2016","journal-title":"J Bone Joint Surg Am"},{"issue":"2","key":"10.1016\/j.otsr.2025.104437_bib0130","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/s00381-021-05409-z","article-title":"Pediatric cervical kyphosis in the MRI era (1984\u20132008) with long-term follow up: literature review","volume":"38","author":"Menezes","year":"2022","journal-title":"Childs Nerv Syst"},{"issue":"4","key":"10.1016\/j.otsr.2025.104437_bib0135","doi-asserted-by":"crossref","first-page":"599","DOI":"10.3171\/2022.2.SPINE211316","article-title":"Proximal and distal reciprocal changes following cervical deformity malalignment correction","volume":"37","author":"Lafage","year":"2022","journal-title":"J Neurosurg Spine"},{"issue":"3","key":"10.1016\/j.otsr.2025.104437_bib0140","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21031171","article-title":"Surgical management of spinal disorders in people with mucopolysaccharidoses","volume":"21","author":"Terai","year":"2020","journal-title":"Int J Mol Sci"},{"issue":"4","key":"10.1016\/j.otsr.2025.104437_bib0145","doi-asserted-by":"crossref","first-page":"e266","DOI":"10.1097\/BPO.0000000000001416","article-title":"Intraoperative use of O-arm in pediatric cervical spine surgery","volume":"40","author":"Verhofste","year":"2020","journal-title":"J Pediatr Orthop"},{"issue":"1","key":"10.1016\/j.otsr.2025.104437_bib0150","doi-asserted-by":"crossref","first-page":"32","DOI":"10.3171\/2022.9.PEDS22319","article-title":"Developing consensus for the management of pediatric cervical spine disorders and stabilization: a modified Delphi study","volume":"31","author":"Dastagirzada","year":"2022","journal-title":"J Neurosurg Pediatr"},{"key":"10.1016\/j.otsr.2025.104437_bib0155","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2022.928276","article-title":"Pediatric neurosurgery AC-after COVID-19: what has really changed? A review of the literature","volume":"10","author":"Noris","year":"2022","journal-title":"Front Pediatr"}],"container-title":["Orthopaedics &amp; Traumatology: Surgery &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1877056825002865?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1877056825002865?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T20:09:21Z","timestamp":1770840561000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1877056825002865"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S1877056825002865"],"URL":"https:\/\/doi.org\/10.1016\/j.otsr.2025.104437","relation":{},"ISSN":["1877-0568"],"issn-type":[{"value":"1877-0568","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pathologies of the cervical spine in skeletal syndromes and dysplasias","name":"articletitle","label":"Article Title"},{"value":"Orthopaedics & Traumatology: Surgery & Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.otsr.2025.104437","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.rcot.2025.05.003","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Masson SAS. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"104437"}}