{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T06:49:57Z","timestamp":1793774997362,"version":"4.6.1"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,28]],"date-time":"2022-08-28T00:00:00Z","timestamp":1661644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004462","name":"Consiglio Nazionale delle Ricerche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004462","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005699","name":"Universit\u00e0 degli Studi del Piemonte Orientale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005699","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018693","name":"Horizon 2020","doi-asserted-by":"publisher","award":["801126"],"award-info":[{"award-number":["801126"]}],"id":[{"id":"10.13039\/100018693","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Photoacoustics"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.pacs.2022.100400","type":"journal-article","created":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T12:51:24Z","timestamp":1661863884000},"page":"100400","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"special_numbering":"C","title":["Early diagnosis of bladder cancer by photoacoustic imaging of tumor-targeted gold nanorods"],"prefix":"10.1016","volume":"28","author":[{"given":"Elisa","family":"Alchera","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Monieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirko","family":"Maturi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Locatelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica","family":"Locatelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Tortorella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelina","family":"Sacchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Corti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Nebuloni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Lucian\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Pederzoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Montorsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Salonia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jithin","family":"Jose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierangela","family":"Giustetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro Comes","family":"Franchini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio","family":"Curnis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Alfano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pacs.2022.100400_bib1","unstructured":"TNM classification of malignant tumors. UICC International Union Against Cancer. 8th edn., G.M. Brierley JD, Wittekind C., Editor. Wiley-Blackwell and UICC: New York, USA. (2017)."},{"issue":"2","key":"10.1016\/j.pacs.2022.100400_bib2","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.eururo.2012.07.033","article-title":"Epidemiology and risk factors of urothelial bladder cancer","volume":"63","author":"Burger","year":"2013","journal-title":"Eur Urol"},{"key":"10.1016\/j.pacs.2022.100400_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.eururo.2019.08.016","article-title":"European Association of Urology Guidelines on Non-muscle-invasive Bladder Cancer (TaT1 and Carcinoma In Situ) - 2019 Update","author":"Babjuk","year":"2019","journal-title":"Eur Urol"},{"issue":"3","key":"10.1016\/j.pacs.2022.100400_bib4","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.eururo.2009.06.028","article-title":"Recurrence and progression of disease in non-muscle-invasive bladder cancer: from epidemiology to treatment strategy","volume":"56","author":"van Rhijn","year":"2009","journal-title":"Eur Urol"},{"issue":"5","key":"10.1016\/j.pacs.2022.100400_bib5","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.urology.2007.01.077","article-title":"Effect of bladder carcinoma location on detection rates by ultrasonography and computed tomography","volume":"69","author":"Ozden","year":"2007","journal-title":"Urology"},{"key":"10.1016\/j.pacs.2022.100400_bib6","unstructured":"\u3008https:\/\/uroweb.org\/guideline\/non-muscle-invasive-bladder-cancer\/#5\u3009, (2020)."},{"issue":"1","key":"10.1016\/j.pacs.2022.100400_bib7","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s12957-018-1310-0","article-title":"Clinical rationale and safety of restaging transurethral resection in indication-stratified patients with high-risk non-muscle-invasive bladder cancer","volume":"16","author":"Zapala","year":"2018","journal-title":"World J Surg Oncol"},{"issue":"11","key":"10.1016\/j.pacs.2022.100400_bib8","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1007\/s40273-014-0194-2","article-title":"The health economics of bladder cancer: an updated review of the published literature","volume":"32","author":"Yeung","year":"2014","journal-title":"PharmacoEconomics"},{"issue":"1","key":"10.1016\/j.pacs.2022.100400_bib9","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s12929-019-0594-x","article-title":"Photoacoustic imaging of cells in a three-dimensional microenvironment","volume":"27","author":"Liu","year":"2020","journal-title":"J Biomed Sci"},{"key":"10.1016\/j.pacs.2022.100400_bib10","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.pacs.2019.05.001","article-title":"Photoacoustic clinical imaging","volume":"14","author":"Steinberg","year":"2019","journal-title":"Photoacoustics"},{"issue":"2","key":"10.1016\/j.pacs.2022.100400_bib11","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1152\/physrev.00049.2010","article-title":"A molecular imaging primer: modalities, imaging agents, and applications","volume":"92","author":"James","year":"2012","journal-title":"Physiol Rev"},{"key":"10.1016\/j.pacs.2022.100400_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.pacs.2020.100207","article-title":"Towards non-contact photoacoustic imaging [review]","volume":"20","author":"Hosseinaee","year":"2020","journal-title":"Photoacoustics"},{"issue":"11\u201312","key":"10.1016\/j.pacs.2022.100400_bib13","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1002\/jbio.201400143","article-title":"Handheld photoacoustic probe to detect both melanoma depth and volume at high speed in vivo","volume":"8","author":"Zhou","year":"2015","journal-title":"J Biophotonics"},{"key":"10.1016\/j.pacs.2022.100400_bib14","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.cbpa.2020.06.008","article-title":"Acoustic-based chemical tools for profiling the tumor microenvironment","volume":"57","author":"Yadav","year":"2020","journal-title":"Curr Opin Chem Biol"},{"key":"10.1016\/j.pacs.2022.100400_bib15","doi-asserted-by":"crossref","first-page":"6889","DOI":"10.1038\/srep06889","article-title":"High-speed intravascular photoacoustic imaging of lipid-laden atherosclerotic plaque enabled by a 2-kHz barium nitrite raman laser","volume":"4","author":"Wang","year":"2014","journal-title":"Sci Rep"},{"issue":"6","key":"10.1016\/j.pacs.2022.100400_bib16","doi-asserted-by":"crossref","DOI":"10.1117\/1.3584847","article-title":"In vivo photoacoustic tomography of mouse cerebral edema induced by cold injury","volume":"16","author":"Xu","year":"2011","journal-title":"J Biomed Opt"},{"issue":"8","key":"10.1016\/j.pacs.2022.100400_bib17","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1038\/nmeth.3929","article-title":"Contrast agents for molecular photoacoustic imaging","volume":"13","author":"Weber","year":"2016","journal-title":"Nat Methods"},{"issue":"5","key":"10.1016\/j.pacs.2022.100400_bib18","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1039\/C8BM01444B","article-title":"Current concepts in nanostructured contrast media development for in vivo photoacoustic imaging","volume":"7","author":"Maturi","year":"2019","journal-title":"Biomater Sci"},{"issue":"9","key":"10.1016\/j.pacs.2022.100400_bib19","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1038\/s41568-018-0038-z","article-title":"Every step of the way: integrins in cancer progression and metastasis","volume":"18","author":"Hamidi","year":"2018","journal-title":"Nat Rev Cancer"},{"issue":"9","key":"10.1016\/j.pacs.2022.100400_bib20","article-title":"Exploring the Role of RGD-Recognizing Integrins in Cancer","volume":"9","author":"Nieberler","year":"2017","journal-title":"Cancers ((Basel))"},{"issue":"2","key":"10.1016\/j.pacs.2022.100400_bib21","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1158\/1541-7786.MCR-12-0300","article-title":"CLT1 targets bladder cancer through integrin alpha5beta1 and CLIC3","volume":"11","author":"Knowles","year":"2013","journal-title":"Mol Cancer Res"},{"issue":"3","key":"10.1016\/j.pacs.2022.100400_bib22","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/bjc.1996.57","article-title":"Correlation between integrin alpha 5 expression and the malignant phenotype of transitional cell carcinoma","volume":"73","author":"Saito","year":"1996","journal-title":"Br J Cancer"},{"key":"10.1016\/j.pacs.2022.100400_bib23","unstructured":"\u3008https:\/\/www.proteinatlas.org\/ENSG00000115414-FN1\/pathology\/urothelial+cancer\u3009."},{"key":"10.1016\/j.pacs.2022.100400_bib24","doi-asserted-by":"crossref","first-page":"418","DOI":"10.4137\/BMI.S294","article-title":"The role of structural extracellular matrix proteins in urothelial bladder cancer (review)","volume":"2","author":"Brunner","year":"2007","journal-title":"Biomark Insights"},{"issue":"5","key":"10.1016\/j.pacs.2022.100400_bib25","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1002\/smll.201202310","article-title":"IsoDGR-Tagged Albumin: A New ?v?3 Selective Carrier for Nanodrug Delivery to Tumors","volume":"9","author":"Curnis","year":"2013","journal-title":"Small"},{"issue":"5","key":"10.1016\/j.pacs.2022.100400_bib26","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1002\/smll.201202310","article-title":"IsoDGR-tagged albumin: a new alphavbeta3 selective carrier for nanodrug delivery to tumors","volume":"9","author":"Curnis","year":"2013","journal-title":"Small"},{"issue":"6","key":"10.1016\/j.pacs.2022.100400_bib27","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1093\/neuonc\/nos132","article-title":"The value of cell line validation","volume":"14","author":"Yung","year":"2012","journal-title":"Neuro-oncology"},{"issue":"1","key":"10.1016\/j.pacs.2022.100400_bib28","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/his.13734","article-title":"Staging of bladder cancer","volume":"74","author":"Magers","year":"2019","journal-title":"Histopathology"},{"issue":"13\u201314","key":"10.1016\/j.pacs.2022.100400_bib29","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1089\/ten.tea.2013.0588","article-title":"Cellular localization, invasion, and turnover are differently influenced by healthy and tumor-derived extracellular matrix","volume":"20","author":"Genovese","year":"2014","journal-title":"Tissue Eng Part A"},{"issue":"98","key":"10.1016\/j.pacs.2022.100400_bib30","doi-asserted-by":"crossref","first-page":"14777","DOI":"10.1039\/C9CC08518A","article-title":"A stapled chromogranin A-derived peptide is a potent dual ligand for integrins alphavbeta6 and alphavbeta8","volume":"55","author":"Nardelli","year":"2019","journal-title":"Chem. Commun. (Camb. )"},{"issue":"2","key":"10.1016\/j.pacs.2022.100400_bib31","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.pacs.2013.08.001","article-title":"Optical wavelength selection for improved spectroscopic photoacoustic imaging","volume":"1","author":"Luke","year":"2013","journal-title":"Photoacoustics"},{"issue":"1","key":"10.1016\/j.pacs.2022.100400_bib32","doi-asserted-by":"crossref","DOI":"10.5334\/jors.334","article-title":"PIVlab \u2013 Towards User-friendly, Affordable and Accurate Digital Particle Image Velocimetry in MATLAB","volume":"2","author":"Thielicke","year":"2014","journal-title":"Journal of open research software"},{"issue":"1","key":"10.1016\/j.pacs.2022.100400_bib33","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1080\/02656736.2020.1771437","article-title":"Influence of natural convection on gold nanorods-assisted photothermal treatment of bladder cancer in mice","volume":"37","author":"Ooi","year":"2020","journal-title":"Int J Hyperthermia"},{"issue":"2","key":"10.1016\/j.pacs.2022.100400_bib34","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3233\/BLC-180167","article-title":"Systematic Review: Characteristics and Preclinical Uses of Bladder Cancer Cell Lines","volume":"4","author":"Zuiverloon","year":"2018","journal-title":"Bladder Cancer"},{"issue":"8","key":"10.1016\/j.pacs.2022.100400_bib35","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0161284","article-title":"Imaging Approach for Longitudinal Evaluation of Bladder Tumor Development in an Orthotopic Murine Model","volume":"11","author":"Scheepbouwer","year":"2016","journal-title":"PLoS One"},{"issue":"17","key":"10.1016\/j.pacs.2022.100400_bib36","doi-asserted-by":"crossref","first-page":"7073","DOI":"10.1158\/0008-5472.CAN-08-1272","article-title":"Isoaspartate-glycine-arginine: A new tumor vasculature-targeting motif","volume":"68","author":"Curnis","year":"2008","journal-title":"Cancer Res"},{"issue":"9","key":"10.1016\/j.pacs.2022.100400_bib37","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073076","article-title":"The human urine metabolome","volume":"8","author":"Bouatra","year":"2013","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.pacs.2022.100400_bib38","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.euo.2020.04.002","article-title":"Sex-specific Alterations in the Urinary and Tissue Microbiome in Therapy-naive Urothelial Bladder Cancer Patients","volume":"3","author":"Pederzoli","year":"2020","journal-title":"Eur Urol Oncol"},{"key":"10.1016\/j.pacs.2022.100400_bib39","unstructured":"\u3008https:\/\/uroweb.org\/guideline\/non-muscle-invasive-bladder-cancer\/#note_228\u3009."},{"issue":"5","key":"10.1016\/j.pacs.2022.100400_bib40","doi-asserted-by":"crossref","DOI":"10.1117\/1.JBO.19.5.056004","article-title":"Deep optical imaging of tissue using the second and third near-infrared spectral windows","volume":"19","author":"Sordillo","year":"2014","journal-title":"J Biomed Opt"},{"issue":"6","key":"10.1016\/j.pacs.2022.100400_bib41","doi-asserted-by":"crossref","DOI":"10.1117\/1.2818045","article-title":"Deep reflection-mode photoacoustic imaging of biological tissue","volume":"12","author":"Song","year":"2007","journal-title":"J Biomed Opt"},{"issue":"8","key":"10.1016\/j.pacs.2022.100400_bib42","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1016\/j.biomaterials.2009.11.079","article-title":"Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rats","volume":"31","author":"Balasubramanian","year":"2010","journal-title":"Biomaterials"},{"issue":"8","key":"10.1016\/j.pacs.2022.100400_bib43","doi-asserted-by":"crossref","DOI":"10.3390\/molecules23081848","article-title":"Histopathology of the Liver, Kidney, and Spleen of Mice Exposed to Gold Nanoparticles","volume":"23","author":"Ibrahim","year":"2018","journal-title":"Molecules"},{"issue":"3","key":"10.1016\/j.pacs.2022.100400_bib44","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.eururo.2021.05.018","article-title":"Is There a Detrimental Effect of Antibiotic Therapy in Patients with Muscle-invasive Bladder Cancer Treated with Neoadjuvant Pembrolizumab?","volume":"80","author":"Pederzoli","year":"2021","journal-title":"Eur Urol"},{"key":"10.1016\/j.pacs.2022.100400_bib45","doi-asserted-by":"crossref","DOI":"10.1021\/acsami.0c15430","article-title":"Multimodal Imaging of Pancreatic Ductal Adenocarcinoma Using Multifunctional Nanoparticles as Contrast Agents","author":"Zhao","year":"2020","journal-title":"ACS Appl Mater Interfaces"},{"key":"10.1016\/j.pacs.2022.100400_bib46","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.colsurfb.2019.03.068","article-title":"Small gold nanorods-loaded hybrid albumin nanoparticles with high photothermal efficacy for tumor ablation","volume":"179","author":"Seo","year":"2019","journal-title":"Colloids Surf B Biointerfaces"},{"issue":"25","key":"10.1016\/j.pacs.2022.100400_bib47","doi-asserted-by":"crossref","first-page":"11656","DOI":"10.7150\/thno.51287","article-title":"Rationally designed dual-plasmonic gold nanorod@cuprous selenide hybrid heterostructures by regioselective overgrowth for in vivo photothermal tumor ablation in the second near-infrared biowindow","volume":"10","author":"Shan","year":"2020","journal-title":"Theranostics"},{"key":"10.1016\/j.pacs.2022.100400_bib48","article-title":"Dual Ultrasound and Photoacoustic Tracking of Magnetically Driven Micromotors: From In Vitro to In Vivo, Adv Healthc","author":"Aziz","year":"2021","journal-title":"Mater"},{"issue":"6","key":"10.1016\/j.pacs.2022.100400_bib49","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/j.eururo.2006.08.025","article-title":"New frontiers in intravesical therapies and drug delivery","volume":"50","author":"Giannantoni","year":"2006","journal-title":"Eur Urol"},{"issue":"1","key":"10.1016\/j.pacs.2022.100400_bib50","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1186\/s12885-018-5134-7","article-title":"ElectroMotive drug administration (EMDA) of Mitomycin C as first-line salvage therapy in high risk \"BCG failure\" non muscle invasive bladder cancer: 3 years follow-up outcomes","volume":"18","author":"Racioppi","year":"2018","journal-title":"BMC Cancer"},{"issue":"34","key":"10.1016\/j.pacs.2022.100400_bib51","doi-asserted-by":"crossref","first-page":"57766","DOI":"10.18632\/oncotarget.17714","article-title":"Insights from animal models of bladder cancer: recent advances, challenges, and opportunities","volume":"8","author":"John","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.pacs.2022.100400_bib52","article-title":"Urothelial Carcinoma In Situ of the Bladder: Correlation of CK20 Expression With Adaptive Immune Resistance, Response to BCG Therapy, and Clinical Outcome","author":"Lombardo","year":"2020","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.1016\/j.pacs.2022.100400_bib53","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ejca.2021.01.001","article-title":"A multimodal molecular imaging approach targeting urokinase plasminogen activator receptor for the diagnosis, resection and surveillance of urothelial cell carcinoma","volume":"146","author":"Baart","year":"2021","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.pacs.2022.100400_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.compbiomed.2021.104881","article-title":"A numerical study to investigate the effects of tumour position on the treatment of bladder cancer in mice using gold nanorods assisted photothermal ablation","volume":"138","author":"Cheong","year":"2021","journal-title":"Comput Biol Med"},{"key":"10.1016\/j.pacs.2022.100400_bib55","article-title":"EM2D9, a monoclonal antibody against Integrin a5b1, has potent antitumor activity on endometrial cancer in vitro and in vivo","author":"Xu","year":"2020","journal-title":"Cancer Lett"},{"issue":"7","key":"10.1016\/j.pacs.2022.100400_bib56","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1007\/s12094-013-1133-y","article-title":"Increased expression of alpha5beta1-integrin is a prognostic marker for patients with gastric cancer","volume":"16","author":"Ren","year":"2014","journal-title":"Clin Transl Oncol"},{"issue":"3","key":"10.1016\/j.pacs.2022.100400_bib57","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/s10549-016-3844-6","article-title":"Therapeutic inhibition of breast cancer bone metastasis progression and lung colonization: breaking the vicious cycle by targeting alpha5beta1 integrin","volume":"157","author":"Yao","year":"2016","journal-title":"Breast Cancer Res Treat"},{"issue":"1","key":"10.1016\/j.pacs.2022.100400_bib58","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3390\/cancers5010027","article-title":"Integrin alpha5beta1, the Fibronectin Receptor, as a Pertinent Therapeutic Target in Solid Tumors","volume":"5","author":"Schaffner","year":"2013","journal-title":"Cancers ((Basel))"},{"issue":"1","key":"10.1016\/j.pacs.2022.100400_bib59","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.biotechadv.2017.11.004","article-title":"alphavbeta3 and alpha5beta1 integrin-specific ligands: From tumor angiogenesis inhibitors to vascularization promoters in regenerative medicine?","volume":"36","author":"Rocha","year":"2018","journal-title":"Biotechnol Adv"}],"container-title":["Photoacoustics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213597922000659?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213597922000659?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T09:20:25Z","timestamp":1761988825000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213597922000659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":59,"alternative-id":["S2213597922000659"],"URL":"https:\/\/doi.org\/10.1016\/j.pacs.2022.100400","relation":{},"ISSN":["2213-5979"],"issn-type":[{"value":"2213-5979","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early diagnosis of bladder cancer by photoacoustic imaging of tumor-targeted gold nanorods","name":"articletitle","label":"Article Title"},{"value":"Photoacoustics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pacs.2022.100400","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s). Published by Elsevier GmbH.","name":"copyright","label":"Copyright"}],"article-number":"100400"}}