{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:20:28Z","timestamp":1792714828682,"version":"4.5.0"},"reference-count":46,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,3]]},"DOI":"10.1016\/j.pain.2005.12.006","type":"journal-article","created":{"date-parts":[[2006,2,10]],"date-time":"2006-02-10T07:29:52Z","timestamp":1139556592000},"page":"43-52","source":"Crossref","is-referenced-by-count":165,"title":["Motor cortex stimulation for long-term relief of chronic neuropathic pain: A 10 year experience"],"prefix":"10.1097","volume":"121","author":[{"given":"Dirk","family":"Rasche","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Ruppolt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Stippich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Unterberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker M.","family":"Tronnier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-6-20210227","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0304-3959(03)00209-4","article-title":"Motor cortex stimulation for central and neuropathic pain: current status.","volume":"104","author":"Brown","year":"2003","journal-title":"Pain"},{"key":"R3-6-20210227","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1227\/01.NEU.0000148905.75845.98","article-title":"Motor cortex stimulation for central and neuropathic facial pain: a prospective study of 10 patients and observations of enhanced sensory and motor function during stimulation.","volume":"56","author":"Brown","year":"2005","journal-title":"Neurosurgery"},{"key":"R4-6-20210227","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3171\/jns.1999.91.1.0121","article-title":"Painful supernumerary phantom arm following motor cortex stimulation for central poststroke pain. Case report.","volume":"91","author":"Canavero","year":"1999","journal-title":"J Neurosurg"},{"key":"R5-6-20210227","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1097\/00002508-200201000-00008","article-title":"Therapeutic extradural cortical stimulation for central and neuropathic pain: a review.","volume":"18","author":"Canavero","year":"2002","journal-title":"Clin J Pain"},{"issue":"3-4","key":"R6-6-20210227","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1159\/000068965","article-title":"Transcranial magnetic cortical stimulation relieves central pain.","volume":"78","author":"Canavero","year":"2002","journal-title":"Stereotact Funct Neurosurg"},{"key":"R7-6-20210227","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0304-3959(99)00245-6","article-title":"Motor cortex stimulation for chronic neuropathic pain: a preliminary study of 10 cases.","volume":"84","author":"Carroll","year":"2000","journal-title":"Pain"},{"key":"R8-6-20210227","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1093\/brain\/awf161","article-title":"The antalgetic effect of chronic motor cortex stimulation is related to sensory changes in the painful zone.","volume":"125","author":"Drouot","year":"2002","journal-title":"Brain"},{"key":"R9-6-20210227","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1007\/BF01411059","article-title":"Chronic precentral stimulation in trigeminal neuropathic pain.","volume":"138","author":"Ebel","year":"1996","journal-title":"Acta Neurochir"},{"key":"R10-6-20210227","first-page":"1435","article-title":"Neuropathic cancer pain: the role of adjuvant analgesics.","volume":"15","author":"Farrar","year":"2001","journal-title":"Oncology (Williston Park)"},{"key":"R11-6-20210227","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s002210050334","article-title":"Cortical reorganization and phantom phenomena in congenital and traumatic upper-extremity amputees.","volume":"119","author":"Flor","year":"1998","journal-title":"Exp Brain Res"},{"issue":"2","key":"R13-6-20210227","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1179\/016164103101201319","article-title":"Motor cortex stimulation in patients with post-stroke pain: conscious somatosensory response and pain control.","volume":"25","author":"Fukaya","year":"2003","journal-title":"Neurol Res"},{"key":"R14-6-20210227","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1159\/000099915","article-title":"Positron emission tomography during motor cortex stimulation for pain control.","volume":"68","author":"Garcia-Larrea","year":"1997","journal-title":"Stereotact Funct Neurosurg"},{"key":"R15-6-20210227","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0304-3959(99)00114-1","article-title":"Electrical stimulation of motor cortex for pain control: a combined PET-scan and electrophysiological study.","volume":"83","author":"Garcia-Larrea","year":"1999","journal-title":"Pain"},{"key":"R16-6-20210227","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/S0188-4409(00)00083-7","article-title":"Functional imaging and neurophysiological assessment of spinal and brain therapeutic modulation in humans.","volume":"31","author":"Garcia-Larrea","year":"2000","journal-title":"Arch Med Res"},{"key":"R17-6-20210227","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/978-3-7091-9419-5_29","article-title":"Cortical stimulation for central neuropathic pain: 3-D surface MRI for easy determination of the motor cortex.","volume":"64","author":"Herregodts","year":"1995","journal-title":"Acta Neurochirur Suppl"},{"key":"R18-6-20210227","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1177\/019459988509300202","article-title":"Facial nerve grading system.","volume":"93","author":"House","year":"1985","journal-title":"Otolaryngol Head Neck Surg"},{"key":"R19-6-20210227","doi-asserted-by":"crossref","first-page":"3609","DOI":"10.1523\/JNEUROSCI.21-10-03609.2001","article-title":"Reorganization of motor and somatosensory cortex in upper extremity amputees with phantom limb pain.","volume":"21","author":"Karl","year":"2001","journal-title":"J Neurosci"},{"key":"RU20-6-20210227","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1159\/000098635","article-title":"Chronic motor cortex stimulation for central deafferentation pain: experience with bulbar pain secondary to Wallenberg syndrome.","volume":"62","author":"Katayama","year":"1994","journal-title":"Stereotact Funct Neurosurg"},{"key":"R21-6-20210227","doi-asserted-by":"crossref","first-page":"585","DOI":"10.3171\/jns.1998.89.4.0585","article-title":"Poststroke pain control by chronic motor cortex stimulation: neurological characteristics predicting a favourable response.","volume":"89","author":"Katayama","year":"1998","journal-title":"J Neurosurg"},{"key":"R22-6-20210227","doi-asserted-by":"crossref","first-page":"210","DOI":"10.3171\/jns.1987.67.2.0210","article-title":"Cortical localisation and monitoring during cerebral operations.","volume":"67","author":"King","year":"1987","journal-title":"J Neurosurg"},{"key":"R23-6-20210227","first-page":"226","article-title":"Electrical stimulation of the second somatosensory cortex for intractable pain: a case report and experimental study.","volume":"74","author":"Kuroda","year":"2000","journal-title":"Stereotact Funct Neurosurg"},{"key":"R24-6-20210227","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1136\/jnnp.2003.022236","article-title":"Neurogenic pain relief by repetitive transcranial magnetic cortical stimulation depends on the origin and the site of pain.","volume":"75","author":"Lefaucheur","year":"2004","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"R25-6-20210227","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1159\/000029769","article-title":"Precentral cortex stimulation for the treatment of central neuropathic pain: results of a prospective study in a 20-patient series.","volume":"73","author":"Mertens","year":"1999","journal-title":"Stereotact Funct Neurosurg"},{"key":"R26-6-20210227","first-page":"150","article-title":"Motor cortex stimulation as treatment of trigeminal neuropathic pain.","volume":"58","author":"Meyerson","year":"1993","journal-title":"Acta Neurochir (Wien) Suppl"},{"key":"R27-6-20210227","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1227\/00006123-199505000-00025","article-title":"Transcranial magnetic coil stimulation of the motor cortex in patients with central pain.","volume":"36","author":"Migita","year":"1995","journal-title":"Neurosurgery"},{"key":"R28-6-20210227","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0304-3959(99)00062-7","article-title":"Chronic motor cortex stimulation in the treatment of central and neuropathic pain. Correlations between clinical, electrophysiological and anatomical data.","volume":"82","author":"Nguyen","year":"1999","journal-title":"Pain"},{"key":"R29-6-20210227","first-page":"483","article-title":"Treatment of central and neuropathic facial pain by chronic stimulation of the motor cortex: value of neuronavigation guidance for the localization of the motor cortex.","volume":"46","author":"Nguyen","year":"2000","journal-title":"Neurochirurgie"},{"issue":"s1","key":"R30-6-20210227","first-page":"126","article-title":"Headache Classification Committee of the International Headache Society. The International Classification of Headache Disorders. 2nd ed.","volume":"24","author":"Olesen","year":"2004","journal-title":"Cephalalgia"},{"key":"R31-6-20210227","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0987-7053(00)00227-6","article-title":"Functional imaging of brain responses to pain. A review and analysis.","volume":"30","author":"Peyron","year":"2000","journal-title":"Neurophysiol Clin"},{"key":"RU32-6-20210227","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1179\/016164103101201328","article-title":"Motor cortex stimulation for neuropathic facial pain.","volume":"25","author":"Rainov","year":"2003","journal-title":"Neurol Res"},{"key":"R33-6-20210227","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1212\/WNL.45.5.919","article-title":"Somatotopic mapping of the human primary motor cortex with functional magnetic resonance imaging.","volume":"45","author":"Rao","year":"1995","journal-title":"Neurology"},{"key":"R34-6-20210227","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1097\/00006123-200103000-00050","article-title":"Chronic motor cortex stimulation for phantom limb pain: a functional magnetic resonance imaging study: technical case report.","volume":"48","author":"Roux","year":"2001","journal-title":"Neurosurgery"},{"key":"RU35-6-20210227","doi-asserted-by":"crossref","first-page":"150","DOI":"10.3171\/jns.2000.92.1.0150","article-title":"Motor cortex stimulation for central and peripheral deafferentation pain.","volume":"92","author":"Saitoh","year":"2000","journal-title":"J Neurosurg"},{"key":"R36-6-20210227","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/foc.2001.11.3.2","article-title":"Motor cortex stimulation for deafferentation pain.","volume":"11","author":"Saitoh","year":"2001","journal-title":"Neurosurg Focus"},{"key":"R37-6-20210227","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1159\/000064616","article-title":"Chronic motor cortex stimulation for phantom limb pain: correlations between pain relief and functional imaging studies.","volume":"77","author":"Sol","year":"2001","journal-title":"Stereotact Funct Neurosurg"},{"key":"R38-6-20210227","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1111\/j.1460-9568.2004.03669.x","article-title":"Transcranial magnetic stimulation of the human motor cortex influences the neuronal activity of subthalamic nucleus.","volume":"20","author":"Starafella","year":"2004","journal-title":"Eur J Neurosci"},{"key":"R39-6-20210227","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/S0304-3940(02)00826-1","article-title":"Somatotopic mapping of the human primary sensorimotor cortex during motor imagery and motor execution by functional magnetic resonance imaging.","volume":"331","author":"Stippich","year":"2002","journal-title":"Neurosci Lett"},{"key":"R40-6-20210227","first-page":"1042","article-title":"Preoperative fMRI in patients with rolandic brain tumors: indication, investigation strategy, possibilities and limitations of clinical application.","volume":"175","author":"Stippich","year":"2003","journal-title":"Fortsch Rontgenstr"},{"key":"R41-6-20210227","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.neulet.2004.04.015","article-title":"Fully automated localization of the human primary somatosensory cortex in one minute by functional magnetic resonance imaging.","volume":"364","author":"Stippich","year":"2004","journal-title":"Neurosci Lett"},{"key":"R42-6-20210227","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.neuroscience.2004.05.020","article-title":"Plastic interactions between hand and face cortical representation in patients with trigeminal neuralgia: a somatosensory-evoked potentials study.","volume":"127","author":"Tinazzi","year":"2004","journal-title":"Neuroscience"},{"key":"RU43-6-20210227","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1055\/s-2004-830092","article-title":"Image-guided motor cortex stimulation in patients with central pain.","volume":"47","author":"Tirakotai","year":"2004","journal-title":"Minim Invas Neurosurg"},{"key":"R44-6-20210227","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/978-3-7091-9160-6_37","article-title":"Chronic motor cortex stimulation for the treatment of central pain.","volume":"52","author":"Tsubokawa","year":"1991","journal-title":"Acta Neurochirur (Wien) Suppl"},{"key":"R45-6-20210227","doi-asserted-by":"crossref","first-page":"393","DOI":"10.3171\/jns.1993.78.3.0393","article-title":"Chronic motor cortex stimulation in patients with thalamic pain.","volume":"78","author":"Tsubokawa","year":"1993","journal-title":"J Neurosurg"},{"key":"R46-6-20210227","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1159\/000070829","article-title":"Motor cortex stimulation in the treatment of deafferentation pain. I. Localisation of the motor cortex.","volume":"79","author":"Velasco","year":"2002","journal-title":"Stereotact Funct Neurosurg"},{"key":"R47-6-20210227","doi-asserted-by":"crossref","first-page":"99","DOI":"10.3171\/jns.1988.68.1.0099","article-title":"Localization of human sensorimotor cortex during surgery by cortical surface recording of somatosensory evoked potentials.","volume":"68","author":"Wood","year":"1988","journal-title":"J Neurosurg"},{"key":"R48-6-20210227","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0304-3959(97)00028-6","article-title":"Pharmacological classification of central post-stroke pain: comparison with the results of chronic motor cortex stimulation therapy.","volume":"72","author":"Yamamoto","year":"1997","journal-title":"Pain"}],"container-title":["Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00006396-200603000-00006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T15:10:15Z","timestamp":1785856215000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00006396-200603000-00006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006]]}},"URL":"https:\/\/doi.org\/10.1016\/j.pain.2005.12.006","relation":{},"ISSN":["0304-3959"],"issn-type":[{"value":"0304-3959","type":"print"}],"subject":[],"published":{"date-parts":[[2006,3]]}}}