{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T21:37:46Z","timestamp":1791236266077,"version":"4.1.0"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["painjournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1016\/j.pain.2013.07.007","type":"journal-article","created":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T02:04:15Z","timestamp":1373940255000},"page":"2344-2352","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":68,"title":["Repeated intramuscular injections of nerve growth factor induced progressive muscle hyperalgesia, facilitated temporal summation, and expanded pain areas"],"prefix":"10.1097","volume":"154","author":[{"given":"Koei","family":"Hayashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichiro","family":"Shiozawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriyuki","family":"Ozaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazue","family":"Mizumura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Graven-Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R10-16-20210126","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/0304-3940(91)90418-S","article-title":"Production of nerve growth factor in rat skeletal muscle.","volume":"132","author":"Amano","year":"1991","journal-title":"Neurosci Lett"},{"key":"R15-16-20210126","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1080\/08990220600856255","article-title":"Pressure pain sensitivity and hardness along human normal and sensitized muscle.","volume":"23","author":"Andersen","year":"2006","journal-title":"Somatosens Mot Res"},{"key":"R20-16-20210126","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s00221-008-1531-5","article-title":"Spatial and temporal aspects of muscle hyperalgesia induced by nerve growth factor in humans.","volume":"191","author":"Andersen","year":"2008","journal-title":"Exp Brain Res"},{"key":"R25-16-20210126","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.pain.2010.04.003","article-title":"Sensitization in patients with painful knee osteoarthritis.","volume":"149","author":"Arendt-Nielsen","year":"2010","journal-title":"PAIN"},{"key":"R30-16-20210126","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1016\/j.pain.2012.04.033","article-title":"NGF-evoked sensitization of muscle fascia nociceptors in humans.","volume":"153","author":"Deising","year":"2012","journal-title":"PAIN"},{"key":"R35-16-20210126","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1097\/AJP.0b013e3182048481","article-title":"Local pain and spreading hyperalgesia induced by intramuscular injection of nerve growth factor are not reduced by local anesthesia of the muscle.","volume":"27","author":"Gerber","year":"2011","journal-title":"Clin J Pain"},{"key":"R40-16-20210126","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/s11916-001-0052-8","article-title":"Classification, epidemiology, and natural history of myofascial pain syndrome.","volume":"5","author":"Gerwin","year":"2001","journal-title":"Curr Pain Headache Rep"},{"key":"R45-16-20210126","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.pain.2005.10.023","article-title":"Referred pain and hyperalgesia in human tendon and muscle belly tissue.","volume":"120","author":"Gibson","year":"2006","journal-title":"PAIN"},{"key":"R50-16-20210126","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/03009740600865980","article-title":"Fundamentals of muscle pain, referred pain, and deep tissue hyperalgesia.","volume":"35","author":"Graven-Nielsen","year":"2006","journal-title":"Scand J Rheumatol"},{"key":"R55-16-20210126","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s00221-004-1937-7","article-title":"Painful and non-painful pressure sensations from human skeletal muscle.","volume":"159","author":"Graven-Nielsen","year":"2004","journal-title":"Exp Brain Res"},{"key":"R60-16-20210126","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.jpain.2011.04.010","article-title":"Involvement of NGF in the rat model of persistent muscle pain associated with taut band.","volume":"12","author":"Hayashi","year":"2011","journal-title":"J Pain"},{"key":"R65-16-20210126","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0304-3940(93)90064-R","article-title":"Appearance of new receptive fields in rat dorsal horn neurons following noxious stimulation of skeletal muscle: a model for referral of muscle pain?","volume":"153","author":"Hoheisel","year":"1993","journal-title":"Neurosci Lett"},{"key":"R70-16-20210126","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.pain.2004.12.020","article-title":"Excitatory and modulatory effects of inflammatory cytokines and neurotrophins on mechanosensitive group IV muscle afferents in the rat.","volume":"114","author":"Hoheisel","year":"2005","journal-title":"PAIN"},{"key":"R75-16-20210126","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.brainres.2007.06.054","article-title":"Sensitization of rat dorsal horn neurons by NGF-induced subthreshold potentials and low-frequency activation. A study employing intracellular recordings in vivo.","volume":"1169","author":"Hoheisel","year":"2007","journal-title":"Brain Res"},{"key":"R80-16-20210126","first-page":"175","article-title":"Observations on referred pain arising from muscle.","volume":"3","author":"Kellgren","year":"1938","journal-title":"Clin Sci"},{"key":"R85-16-20210126","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0166-2236(93)90092-Z","article-title":"Nerve growth factor and nociception.","volume":"16","author":"Lewin","year":"1993","journal-title":"Trends Neurosci"},{"key":"R90-16-20210126","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1038\/206097a0","article-title":"Responses of single dorsal cord cells to peripheral cutaneous unmyelinated fibres.","volume":"206","author":"Mendell","year":"1965","journal-title":"Nature"},{"key":"R95-16-20210126","doi-asserted-by":"crossref","first-page":"3752","DOI":"10.1523\/JNEUROSCI.3803-09.2010","article-title":"Bradykinin and nerve growth factor play pivotal roles in muscular mechanical hyperalgesia after exercise (delayed-onset muscle soreness).","volume":"30","author":"Murase","year":"2010","journal-title":"J Neurosci"},{"key":"R100-16-20210126","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.jpain.2005.01.352","article-title":"Temporal summation of pain evoked by mechanical stimulation in deep and superficial tissue.","volume":"6","author":"Nie","year":"2005","journal-title":"J Pain"},{"key":"R105-16-20210126","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1007\/s00221-005-0196-6","article-title":"Enhanced temporal summation of pressure pain in the trapezius muscle after delayed onset muscle soreness.","volume":"170","author":"Nie","year":"2006","journal-title":"Exp Brain Res"},{"key":"R110-16-20210126","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/j.ejpain.2008.06.015","article-title":"Temporal summation of pressure pain during muscle hyperalgesia evoked by nerve growth factor and eccentric contractions.","volume":"13","author":"Nie","year":"2009","journal-title":"Eur J Pain"},{"key":"R115-16-20210126","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1146\/annurev.neuro.29.051605.112929","article-title":"Neurotrophins: mediators and modulators of pain.","volume":"29","author":"Pezet","year":"2006","journal-title":"Annu Rev Neurosci"},{"key":"R125-16-20210126","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S1090-3801(02)00141-6","article-title":"Experimental deep tissue pain in wrist extensors - a model of lateral epicondylalgia.","volume":"7","author":"Slater","year":"2003","journal-title":"Eur J Pain"},{"key":"R130-16-20210126","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/1097-4598(200101)24:1<37::AID-MUS4>3.0.CO;2-8","article-title":"Unilateral intramuscular injections of acidic saline produce a bilateral, long-lasting hyperalgesia.","volume":"24","author":"Sluka","year":"2001","journal-title":"Muscle Nerve"},{"key":"R135-16-20210126","first-page":"152","article-title":"Hyperexcitability in fibromyalgia.","volume":"25","author":"Sorensen","year":"1998","journal-title":"J Rheumatol"},{"key":"R140-16-20210126","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/s0304-3959(02)00344-5","article-title":"Temporal summation of pain from mechanical stimulation of muscle tissue in normal controls and subjects with fibromyalgia syndrome.","volume":"102","author":"Staud","year":"2003","journal-title":"PAIN"},{"key":"R145-16-20210126","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1016\/j.ejpain.2008.02.002","article-title":"Brain activity associated with slow temporal summation of C-fiber evoked pain in fibromyalgia patients and healthy controls.","volume":"12","author":"Staud","year":"2008","journal-title":"Eur J Pain"},{"key":"R150-16-20210126","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0304-3959(03)00012-5","article-title":"Injection of nerve growth factor into human masseter muscle evokes long-lasting mechanical allodynia and hyperalgesia.","volume":"104","author":"Svensson","year":"2003","journal-title":"PAIN"},{"key":"R155-16-20210126","first-page":"340","article-title":"Nerve growth factor-evoked masseter muscle sensitization and perturbation of jaw motor function in healthy women.","volume":"22","author":"Svensson","year":"2008","journal-title":"J Orofac Pain"},{"key":"R160-16-20210126","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00221-008-1399-4","article-title":"Effects of NGF-induced muscle sensitization on proprioception and nociception.","volume":"189","author":"Svensson","year":"2008","journal-title":"Exp Brain Res"},{"key":"R165-16-20210126","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.pain.2009.12.009","article-title":"Human nerve growth factor sensitizes masseter muscle nociceptors in female rats.","volume":"148","author":"Svensson","year":"2010","journal-title":"PAIN"},{"key":"R170-16-20210126","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.pain.2007.11.015","article-title":"Dorsal horn neurons having input from low back structures in rats.","volume":"138","author":"Taguchi","year":"2008","journal-title":"PAIN"},{"key":"R175-16-20210126","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1097\/ALN.0b013e318190bc84","article-title":"Expression profile of nerve growth factor after muscle incision in the rat.","volume":"110","author":"Wu","year":"2009","journal-title":"Anesthesiology"}],"container-title":["Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1016\/j.pain.2013.07.007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T04:47:09Z","timestamp":1623818829000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00006396-201311000-00016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":33,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1016\/j.pain.2013.07.007","relation":{},"ISSN":["0304-3959"],"issn-type":[{"value":"0304-3959","type":"print"}],"subject":[],"published":{"date-parts":[[2013,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Repeated intramuscular injections of nerve growth factor induced progressive muscle hyperalgesia, facilitated temporal summation, and expanded pain areas","name":"articletitle","label":"Article Title"},{"value":"PAIN\u00ae","name":"journaltitle","label":"Journal Title"},{"value":"http:\/\/dx.doi.org\/10.1016\/j.pain.2013.07.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}