{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:39:20Z","timestamp":1762101560297,"version":"3.37.3"},"reference-count":52,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["painjournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1016\/j.pain.2014.05.019","type":"journal-article","created":{"date-parts":[[2014,5,23]],"date-time":"2014-05-23T15:00:51Z","timestamp":1400857251000},"page":"1649-1658","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Association of acetazolamide infusion with headache and cranial artery dilation in healthy volunteers"],"prefix":"10.1097","volume":"155","author":[{"given":"Nanna","family":"Arngrim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik Winther","family":"Schytz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Sohail","family":"Asghar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faisal Mohammad","family":"Amin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anders","family":"Hougaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vibeke Andr\u00e9e","family":"Larsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick J.H.","family":"de Koning","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik Bo Wiberg","family":"Larsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jes","family":"Olesen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Messoud","family":"Ashina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-28-20210126","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1177\/0333102411431333","article-title":"Headache and prolonged dilatation of the middle meningeal artery by PACAP38 in healthy volunteers.","volume":"32","author":"Amin","year":"2012","journal-title":"Cephalalgia"},{"key":"R2-28-20210126","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/S1474-4422(13)70067-X","article-title":"Magnetic resonance angiography of intracranial and extracranial arteries in patients with spontaneous migraine without aura: a cross-sectional study.","volume":"12","author":"Amin","year":"2013","journal-title":"Lancet Neurol"},{"key":"R3-28-20210126","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1002\/ana.22292","article-title":"Evidence for a vascular factor in migraine.","volume":"69","author":"Asghar","year":"2011","journal-title":"Ann Neurol"},{"key":"R4-28-20210126","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1212\/WNL.0b013e3181f9626a","article-title":"Dilation by CGRP of middle meningeal artery and reversal by sumatriptan in normal volunteers.","volume":"75","author":"Asghar","year":"2010","journal-title":"Neurology"},{"key":"R5-28-20210126","first-page":"921","article-title":"Pharmacological modulation of the BOLD response: a study of acetazolamide and glyceryl trinitrate in humans.","volume":"34","author":"Asghar","year":"2011","journal-title":"J Magn Reson"},{"key":"R6-28-20210126","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1093\/brain\/123.9.1830","article-title":"Nitric oxide-induced headache in patients with chronic tension-type headache.","volume":"123","author":"Ashina","year":"2000","journal-title":"Brain"},{"key":"R7-28-20210126","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1177\/0333102410394672","article-title":"Lack of correlation between vasodilatation and pharmacologically induced immediate headache in healthy subjects.","volume":"31","author":"Ashina","year":"2011","journal-title":"Cephalalgia"},{"key":"R8-28-20210126","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0002-9394(54)92027-9","article-title":"Decrease in intraocular pressure in man by a carbonic anhydrase inhibitor, diamox.","volume":"37","author":"Becker","year":"1954","journal-title":"Am J Ophthalmol"},{"key":"R9-28-20210126","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1152\/jn.1998.79.2.964","article-title":"Chemical stimulation of the intracranial dura induces enhanced responses to facial stimulation in brain stem trigeminal neurons.","volume":"79","author":"Burstein","year":"1998","journal-title":"J Neurophysiol"},{"key":"R10-28-20210126","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1111\/head.12150","article-title":"Sex differences in the prevalence, symptoms, and associated features of migraine, probable migraine and other severe headache: results of the American Migraine Prevalence and Prevention (AMPP) Study.","volume":"53","author":"Buse","year":"2013","journal-title":"Headache"},{"key":"R11-28-20210126","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1046\/j.1468-2982.1999.019007660.x","article-title":"Glyceryl trinitrate induces attacks of migraine without aura in sufferers of migraine with aura.","volume":"19","author":"Christiansen","year":"1999","journal-title":"Cephalalgia"},{"key":"R12-28-20210126","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1093\/brain\/awl351","article-title":"Interictal habituation deficit of the nociceptive blink reflex: an endophenotypic marker for presymptomatic migraine?","volume":"130","author":"Di Clemente","year":"2007","journal-title":"Brain"},{"key":"R13-28-20210126","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1038\/jcbfm.1994.130","article-title":"Simultaneous assessment of vasoreactivity using transcranial Doppler ultrasound and cerebral blood flow in healthy subjects.","volume":"14","author":"Dahl","year":"1994","journal-title":"J Cereb Blood Flow Metab"},{"key":"R14-28-20210126","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1111\/j.1468-2982.2009.01887.x","article-title":"Delayed migraine-like headache in healthy volunteers after a combination of acetazolamide and glyceryl trinitrate.","volume":"29","author":"Daugaard","year":"2009","journal-title":"Cephalalgia"},{"key":"R15-28-20210126","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1161\/01.STR.30.1.76","article-title":"Influence of acetazolamide and CO2 on extracranial flow volume and intracranial blood flow velocity.","volume":"30","author":"Eicke","year":"1999","journal-title":"Stroke"},{"key":"R16-28-20210126","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1001\/archneur.1968.00480050057005","article-title":"Nitroglycerin as a provocative agent in cluster headache.","volume":"19","author":"Ekbom","year":"1968","journal-title":"Arch Neurol"},{"key":"R17-28-20210126","first-page":"H954","article-title":"Cerebral blood flow and end-tidal PCO2 during prolonged acetazolamide treatment in humans.","volume":"258","author":"Friberg","year":"1990","journal-title":"Am J Physiol"},{"key":"R18-28-20210126","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1111\/j.1468-2982.2006.01257.x","article-title":"Magnetic resonance angiography shows dilatation of the middle cerebral artery after infusion of glyceryl trinitrate in healthy volunteers.","volume":"27","author":"Hansen","year":"2007","journal-title":"Cephalalgia"},{"key":"R19-28-20210126","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1111\/j.1468-2982.2006.01149.x","article-title":"Vasoactive intestinal polypeptide evokes only a minimal headache in healthy volunteers.","volume":"26","author":"Hansen","year":"2006","journal-title":"Cephalalgia"},{"key":"R20-28-20210126","doi-asserted-by":"crossref","first-page":"205","DOI":"10.2165\/00003088-200342030-00001","article-title":"Clinical pharmacokinetics and pharmacodynamics of glyceryl trinitrate and its metabolites.","volume":"42","author":"Hashimoto","year":"2003","journal-title":"Clin Pharmacokinet"},{"key":"R21-28-20210126","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1177\/0333102413485658","article-title":"The International Classification of Headache Disorders, 3rd edition (beta version).","volume":"33","year":"2013","journal-title":"Cephalalgia"},{"key":"R22-28-20210126","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0304-3959(89)90067-5","article-title":"Intravenous nitroglycerin as an experimental model of vascular headache. Basic characteristics.","volume":"38","author":"Iversen","year":"1989","journal-title":"PAIN"},{"key":"R23-28-20210126","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1046\/j.1468-2982.1996.1605310.x","article-title":"Calcitonin gene-related peptide is released from capsaicin-sensitive nerve fibres and induces vasodilatation of human cerebral arteries concomitant with activation of adenylyl cyclase.","volume":"16","author":"Jansen-Olesen","year":"1996","journal-title":"Cephalalgia"},{"key":"R24-28-20210126","first-page":"R1661","article-title":"Acetazolamide-induced cerebral and ocular vasodilation in humans is independent of nitric oxide.","volume":"276","author":"Kiss","year":"1999","journal-title":"Am J Physiol"},{"key":"R25-28-20210126","doi-asserted-by":"crossref","first-page":"313","DOI":"10.2176\/nmc.37.313","article-title":"Brain pH responses to acetazolamide and hypercapnia in cats.","volume":"37","author":"Kohshi","year":"1997","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"R26-28-20210126","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1152\/jappl.1994.76.5.2199","article-title":"In situ arterial and brain tissue PCO2 responses to acetazolamide in cats.","volume":"76","author":"Kohshi","year":"1994","journal-title":"J Appl Physiol"},{"key":"R27-28-20210126","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1161\/01.STR.8.3.358","article-title":"Analysis of vasoactivity of local pH, PCO2 and bicarbonate on pial vessels.","volume":"8","author":"Kontos","year":"1977","journal-title":"Stroke"},{"key":"R28-28-20210126","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0167-0115(85)90013-8","article-title":"Infusion of a novel peptide, calcitonin gene-related peptide (CGRP) in man. Pharmacokinetics and effects on gastric acid secretion and on gastrointestinal hormones.","volume":"10","author":"Kraenzlin","year":"1985","journal-title":"Regul Pept"},{"key":"R29-28-20210126","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/j.1468-2982.2004.00862.x","article-title":"The effect of i.v. L-NG methylarginine hydrochloride (L-NMMA: 546C88) on basal and acetazolamide (Diamox) induced changes of blood velocity in cerebral arteries and regional cerebral blood flow in man.","volume":"25","author":"Lassen","year":"2004","journal-title":"Cephalalgia"},{"key":"R30-28-20210126","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1152\/japplphysiol.01572.2005","article-title":"Mechanisms of action of acetazolamide in the prophylaxis and treatment of acute mountain sickness.","volume":"102","author":"Leaf","year":"2007","journal-title":"J Appl Physiol"},{"key":"R31-28-20210126","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1021\/cn100094b","article-title":"ASIC3 channels in multimodal sensory perception.","volume":"2","author":"Li","year":"2011","journal-title":"ACS Chem Neurosci"},{"key":"R32-28-20210126","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1358\/dot.1998.34.6.485254","article-title":"Pseudotumor cerebri and its medical treatment.","volume":"34","author":"Liu","year":"1998","journal-title":"Drugs Today (Barc)"},{"key":"R33-28-20210126","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1161\/01.STR.25.9.1807","article-title":"Evaluation of cerebral vasoreactivity by three-dimensional time-of-flight magnetic resonance angiography.","volume":"25","author":"Mandai","year":"1994","journal-title":"Stroke"},{"key":"R34-28-20210126","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1136\/bmj.300.6719.230","article-title":"Analysis of serial measurements in medical research.","volume":"300","author":"Matthews","year":"1990","journal-title":"BMJ"},{"key":"R35-28-20210126","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.pharmthera.2008.08.003","article-title":"The role of nitric oxide (NO) in migraine, tension-type headache and cluster headache.","volume":"120","author":"Olesen","year":"2008","journal-title":"Pharmacol Ther"},{"key":"R36-28-20210126","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.clpt.2004.10.001","article-title":"BIBN4096BS antagonizes human alpha-calcitonin gene related peptide-induced headache and extracerebral artery dilatation.","volume":"77","author":"Petersen","year":"2005","journal-title":"Clin Pharmacol Ther"},{"key":"R37-28-20210126","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1038\/sj.bjp.0703825","article-title":"In vivo evidence for K(Ca) channel opening properties of acetazolamide in the human vasculature.","volume":"132","author":"Pickkers","year":"2001","journal-title":"Br J Pharmacol"},{"key":"R38-28-20210126","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/j.1468-2982.2007.01497.x","article-title":"Vasoactive intestinal peptide causes marked cephalic vasodilation, but does not induce migraine.","volume":"28","author":"Rahmann","year":"2008","journal-title":"Cephalalgia"},{"key":"R39-28-20210126","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1177\/033310240102100708","article-title":"Epidemiology of headache.","volume":"21","author":"Rasmussen","year":"2001","journal-title":"Cephalalgia"},{"key":"R40-28-20210126","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/jcbfm.1992.20","article-title":"Evaluation of cerebral vasomotor reactivity by various vasodilating stimuli: comparison of CO2 to acetazolamide.","volume":"12","author":"Ringelstein","year":"1992","journal-title":"J Cereb Blood Flow Metab"},{"key":"R41-28-20210126","first-page":"1207","article-title":"Assessment of blood flow velocity and diameter of the middle cerebral artery during the acetazolamide provocation test by use of transcranial Doppler sonography and MR imaging.","volume":"21","author":"Schreiber","year":"2000","journal-title":"AJNR Am J Neuroradiol"},{"key":"R42-28-20210126","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/brain\/awn307","article-title":"PACAP38 induces migraine-like attacks in patients with migraine without aura.","volume":"132","author":"Schytz","year":"2009","journal-title":"Brain"},{"key":"R43-28-20210126","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/j.1468-1331.2008.02398.x","article-title":"Changes in cerebral blood flow after acetazolamide: an experimental study comparing near-infrared spectroscopy and SPECT.","volume":"16","author":"Schytz","year":"2009","journal-title":"Eur J Neurolol"},{"key":"R44-28-20210126","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/j.1468-2982.2008.01715.x","article-title":"The cholinomimetic agent carbachol induces headache in healthy subjects.","volume":"29","author":"Schytz","year":"2009","journal-title":"Cephalalgia"},{"key":"R45-28-20210126","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1046\/j.1526-4610.1996.3610589.x","article-title":"Acetazolamide testing of cerebral vasodilator capacity provokes vascular but not tension headaches.","volume":"36","author":"Shirai","year":"1996","journal-title":"Headache"},{"key":"R46-28-20210126","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/BF01772826","article-title":"Effect of acetazolamide on cerebral artery blood velocity and regional cerebral blood flow in normal subjects.","volume":"97","author":"Sorteberg","year":"1989","journal-title":"Acta Neurochir"},{"key":"R47-28-20210126","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1523\/JNEUROSCI.12-01-00086.1992","article-title":"Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro.","volume":"12","author":"Steen","year":"1992","journal-title":"J Neurosci"},{"key":"R48-28-20210126","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1038\/384560a0","article-title":"Sensitization of meningeal sensory neurons and the origin of headaches.","volume":"384","author":"Strassman","year":"1996","journal-title":"Nature"},{"key":"R49-28-20210126","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1007\/BF02583501","article-title":"Effects of acetazolamide on medullary extracellular pH and PCO2 and on ventilation in peripherally chemodenervated cats.","volume":"415","author":"Teppema","year":"1990","journal-title":"Pflugers Arch"},{"key":"R50-28-20210126","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1172\/JCI111579","article-title":"Effect of acetazolamide on cerebral blood flow and cerebral metabolic rate for oxygen.","volume":"74","author":"Vorstrup","year":"1984","journal-title":"J Clin Invest"},{"key":"R51-28-20210126","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1111\/head.12152","article-title":"PH-evoked dural afferent signaling is mediated by ASIC3 and is sensitized by mast cell mediators.","volume":"53","author":"Yan","year":"2013","journal-title":"Headache"},{"key":"R52-28-20210126","doi-asserted-by":"crossref","first-page":"89","DOI":"10.18433\/J3QG7Z","article-title":"Population pharmacokinetic and pharmacodynamic modeling of acetazolamide in peritoneal dialysis patients and healthy volunteers.","volume":"16","author":"Yue","year":"2013","journal-title":"J Pharm Pharm Sci"}],"container-title":["Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1016\/j.pain.2014.05.019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T04:49:43Z","timestamp":1623818983000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00006396-201408000-00028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":52,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1016\/j.pain.2014.05.019","relation":{},"ISSN":["0304-3959"],"issn-type":[{"type":"print","value":"0304-3959"}],"subject":[],"published":{"date-parts":[[2014,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of acetazolamide infusion with headache and cranial artery dilation in healthy volunteers","name":"articletitle","label":"Article Title"},{"value":"PAIN\u00ae","name":"journaltitle","label":"Journal Title"},{"value":"http:\/\/dx.doi.org\/10.1016\/j.pain.2014.05.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}