{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T22:46:27Z","timestamp":1794091587556,"version":"4.8.0"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["painjournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.pain.2014.05.029","type":"journal-article","created":{"date-parts":[[2014,6,5]],"date-time":"2014-06-05T13:52:41Z","timestamp":1401976361000},"page":"1755-1761","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":100,"title":["Inflammation and inflammatory control in interstitial cystitis\/bladder pain syndrome: Associations with painful symptoms"],"prefix":"10.1097","volume":"155","author":[{"given":"Andrew","family":"Schrepf","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"O\u2019Donnell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine S.","family":"Bradley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Kreder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Lutgendorf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-11-20210126","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/s00192-010-1252-8","article-title":"Treatment choice, duration, and cost in patients with interstitial cystitis and painful bladder syndrome.","volume":"22","author":"Anger","year":"2011","journal-title":"Int Urogynecol J"},{"key":"R2-11-20210126","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.neulet.2013.03.014","article-title":"A minocycline derivative reduces nerve injury-induced allodynia, LPS-induced prostaglandin E2 microglial production and signaling via toll-like receptors 2 and 4.","volume":"543","author":"Bastos","year":"2013","journal-title":"Neurosci Lett"},{"key":"R3-11-20210126","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.juro.2011.03.132","article-title":"Prevalence of symptoms of bladder pain syndromeinterstitial cystitis among adult females in the United States.","volume":"186","author":"Berry","year":"2011","journal-title":"J Urol"},{"key":"R4-11-20210126","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.4049\/jimmunol.0902383","article-title":"17Beta-estradiol promotes TLR4-triggered proinflammatory mediator production through direct estrogen receptor alpha signaling in macrophages in vivo.","volume":"185","author":"Calippe","year":"2010","journal-title":"J Immunol"},{"key":"R5-11-20210126","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/1043-4666(91)90497-2","article-title":"Altered cytokine release in peripheral blood mononuclear cell cultures from patients with the chronic fatigue syndrome.","volume":"3","author":"Chao","year":"1991","journal-title":"Cytokine"},{"key":"R6-11-20210126","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0022-3956(96)00051-9","article-title":"The relationship between fibromyalgia and interstitial cystitis.","volume":"31","author":"Clauw","year":"1997","journal-title":"J Psychiatr Res"},{"key":"R7-11-20210126","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/j.urology.2009.06.078","article-title":"Urologic Pelvic Pain Collaborative Research Network. Validation of a modified National Institutes of Health chronic prostatitis symptom index to assess genitourinary pain in both men and women.","volume":"74","author":"Clemens","year":"2009","journal-title":"Urology"},{"key":"R8-11-20210126","doi-asserted-by":"crossref","first-page":"e84159","DOI":"10.1371\/journal.pone.0084159","article-title":"Systemic inflammation decreases pain threshold in humans in vivo.","volume":"8","author":"de Goeij","year":"2013","journal-title":"PLoS One"},{"key":"R9-11-20210126","first-page":"237","article-title":"Rome III: new standard for functional gastrointestinal disorders.","volume":"15","author":"Drossman","year":"2006","journal-title":"J Gastrointest Liver Dis"},{"key":"R11-11-20210126","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1038\/sj.ijo.0801792","article-title":"The relation of body fat mass and distribution to markers of chronic inflammation.","volume":"25","author":"Festa","year":"2001","journal-title":"Int J Obes Relat Metab Disord"},{"key":"R12-11-20210126","doi-asserted-by":"crossref","first-page":"953","DOI":"10.7326\/0003-4819-121-12-199412150-00009","article-title":"The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group.","volume":"121","author":"Fukuda","year":"1994","journal-title":"Ann Intern Med"},{"key":"R13-11-20210126","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1100\/tsw.2007.230","article-title":"Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence, and reward.","volume":"7","author":"Hutchinson","year":"2007","journal-title":"Sci World J"},{"key":"R14-11-20210126","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/j.1460-9568.2008.06321.x","article-title":"Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4).","volume":"28","author":"Hutchinson","year":"2008","journal-title":"Eur J Neurosci"},{"key":"R15-11-20210126","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1111\/j.1365-2362.2010.02407.x","article-title":"Impaired anti-inflammatory efficacy of N-butyrate in patients with IBD.","volume":"41","author":"Kovarik","year":"2011","journal-title":"Eur J Clin Invest"},{"key":"R17-11-20210126","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1097\/01.JGP.0000201816.26786.5b","article-title":"Design decisions to optimize reliability of daytime cortisol slopes in an older population.","volume":"14","author":"Kraemer","year":"2006","journal-title":"Am J Geriatr Psychiatry"},{"key":"R18-11-20210126","doi-asserted-by":"crossref","first-page":"e44232","DOI":"10.1371\/journal.pone.0044232","article-title":"Increased responsiveness of peripheral blood mononuclear cells to in vitro TLR 2, 4 and 7 ligand in chronic pain patients.","volume":"7","author":"Kwok","year":"2012","journal-title":"PLoS One"},{"key":"R19-11-20210126","doi-asserted-by":"crossref","first-page":"e77799","DOI":"10.1371\/journal.pone.0077799","article-title":"TLR 2 and 4 responsiveness from isolated peripheral blood mononuclear cells from rats and humans as potential chronic pain biomarkers.","volume":"8","author":"Kwok","year":"2013","journal-title":"PLoS One"},{"key":"R20-11-20210126","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1016\/j.bbi.2011.04.013","article-title":"Prior exposure to glucocorticoids potentiates lipopolysaccharide induced mechanical allodynia and spinal neuroinflammation.","volume":"25","author":"Loram","year":"2011","journal-title":"Brain Behav Immun"},{"key":"R21-11-20210126","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1016\/S0022-5347(05)65295-0","article-title":"Diurnal cortisol variations and symptoms in patients with interstitial cystitis.","volume":"167","author":"Lutgendorf","year":"2002","journal-title":"J Urol"},{"key":"R22-11-20210126","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/nrn2533","article-title":"Pathological and protective roles of glia in chronic pain.","volume":"10","author":"Milligan","year":"2009","journal-title":"Nat Rev Neurosci"},{"key":"R23-11-20210126","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.juro.2013.08.024","article-title":"An endogenous pain control system is altered in subjects with interstitial cystitis.","volume":"191","author":"Ness","year":"2014","journal-title":"J Urol"},{"key":"R24-11-20210126","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.juro.2009.02.122","article-title":"Clinical phenotyping of women with interstitial cystitispainful bladder syndrome: a key to classification and potentially improved management.","volume":"182","author":"Nickel","year":"2009","journal-title":"J Urol"},{"key":"R25-11-20210126","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.expneurol.2011.09.038","article-title":"Toll-like receptors in chronic pain.","volume":"234","author":"Nicotra","year":"2012","journal-title":"Exp Neurol"},{"key":"R26-11-20210126","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1097\/01.ju.0000169258.31345.5d","article-title":"Risk of irritable bowel syndrome and depression in women with interstitial cystitis: a case-control study.","volume":"174","author":"Novi","year":"2005","journal-title":"J Urol"},{"key":"R27-11-20210126","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/S0090-4295(99)80333-1","article-title":"The interstitial cystitis symptom index and problem index.","volume":"49","author":"OLeary","year":"1997","journal-title":"Urology"},{"key":"R28-11-20210126","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1001\/jama.2009.1091","article-title":"Sexual abuse and lifetime diagnosis of somatic disorders: a systematic review and meta-analysis.","volume":"302","author":"Paras","year":"2009","journal-title":"JAMA"},{"key":"R29-11-20210126","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.pain.2011.10.005","article-title":"Urologic chronic pelvic pain.","volume":"153","author":"Potts","year":"2012","journal-title":"PAIN"},{"key":"R30-11-20210126","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1097\/01.ju.0000176747.40242.3d","article-title":"Menstrual cycle affects bladder pain sensation in subjects with interstitial cystitis.","volume":"174","author":"Powell-Boone","year":"2005","journal-title":"J Urol"},{"key":"R31-11-20210126","first-page":"1434","article-title":"A prospective study of interstitial cystitis: results of longitudinal followup of the interstitial cystitis data base cohort.","volume":"63","author":"Propert","year":"2000","journal-title":"J Urol"},{"key":"R32-11-20210126","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1080\/009262300278597","article-title":"The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function.","volume":"26","author":"Rosen","year":"2000","journal-title":"J Sex Marital Ther"},{"key":"R33-11-20210126","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/S0090-4295(00)00988-2","article-title":"Stress and symptoms in patients with interstitial cystitis: a life stress model.","volume":"57","author":"Rothrock","year":"2001","journal-title":"Urology"},{"key":"R34-11-20210126","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1152\/physiolgenomics.00128.2011","article-title":"Transcriptional implications of ultradian glucocorticoid secretion in homeostasis and in the acute stress response.","volume":"44","author":"Scheff","year":"2012","journal-title":"Physiol Genomics"},{"key":"R35-11-20210126","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.pain.2008.01.008","article-title":"The effects of anxiety and depression on weekly pain in women with arthritis.","volume":"138","author":"Smith","year":"2008","journal-title":"PAIN"},{"key":"R36-11-20210126","doi-asserted-by":"crossref","first-page":"15450","DOI":"10.1523\/JNEUROSCI.3859-11.2011","article-title":"Spinal cord Toll-like receptor 4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice.","volume":"31","author":"Sorge","year":"2011","journal-title":"J Neurosci"},{"key":"R37-11-20210126","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1186\/1742-2094-10-148","article-title":"Toll-like receptor signaling adapter proteins govern spread of neuropathic pain and recovery following nerve injury in male mice.","volume":"10","author":"Stokes","year":"2013","journal-title":"J Neuroinflammation"},{"key":"R38-11-20210126","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.pain.2008.01.018","article-title":"Effects of mood on pain responses and pain tolerance: an experimental study in chronic back pain patients.","volume":"138","author":"Tang","year":"2008","journal-title":"PAIN"},{"key":"R39-11-20210126","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1016\/j.psyneuen.2008.05.002","article-title":"Higher body mass index (BMI) is associated with reduced glucocorticoid inhibition of inflammatory cytokine production following acute psychosocial stress in men.","volume":"33","author":"Wirtz","year":"2008","journal-title":"Psychoneuroendocrinology"},{"key":"R40-11-20210126","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1002\/acr.20140","article-title":"The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity.","volume":"62","author":"Wolfe","year":"2010","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"R41-11-20210126","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1016\/j.pain.2010.09.030","article-title":"Central sensitization: implications for the diagnosis and treatment of pain.","volume":"152","author":"Woolf","year":"2011","journal-title":"PAIN"}],"container-title":["Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1016\/j.pain.2014.05.029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T00:49:47Z","timestamp":1623804587000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00006396-201409000-00011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":39,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1016\/j.pain.2014.05.029","relation":{},"ISSN":["0304-3959"],"issn-type":[{"value":"0304-3959","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inflammation and inflammatory control in interstitial cystitis\/bladder pain syndrome: Associations with painful symptoms","name":"articletitle","label":"Article Title"},{"value":"PAIN\u00ae","name":"journaltitle","label":"Journal Title"},{"value":"http:\/\/dx.doi.org\/10.1016\/j.pain.2014.05.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}