{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T22:47:50Z","timestamp":1784242070567,"version":"3.55.0"},"reference-count":45,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100007827","name":"American College of Gastroenterology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007827","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["U01DK108327"],"award-info":[{"award-number":["U01DK108327"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center For Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR002733"],"award-info":[{"award-number":["UL1TR002733"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pancreatology"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1016\/j.pan.2020.04.018","type":"journal-article","created":{"date-parts":[[2020,6,6]],"date-time":"2020-06-06T18:27:15Z","timestamp":1591468035000},"page":"852-859","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Reduction of inflammation in chronic pancreatitis using a soy bread intervention: A feasibility study"],"prefix":"10.1016","volume":"20","author":[{"given":"Jennifer","family":"Ahn-Jarvis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin","family":"Lombardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zobeida","family":"Cruz-Monserrate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niharika","family":"Badi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Crowe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Kaul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Komar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somashekar G.","family":"Krishna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory B.","family":"Lesinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas A.","family":"Mace","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell L.","family":"Ramsey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle","family":"Stinehart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madelyn","family":"Traczek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darwin L.","family":"Conwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yael","family":"Vodovotz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phil A.","family":"Hart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pan.2020.04.018_bib1","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.pan.2016.02.001","article-title":"Chronic pancreatitis: an international draft consensus proposal for a new mechanistic definition","volume":"16","author":"Whitcomb","year":"2016","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2020.04.018_bib2","doi-asserted-by":"crossref","first-page":"49","DOI":"10.14309\/ajg.0000000000000421","article-title":"Chronic pancreatitis: managing a difficult disease","volume":"115","author":"Hart","year":"2019","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.pan.2020.04.018_bib3","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1007\/s10620-017-4518-x","article-title":"Complications of chronic pancreatitis","volume":"62","author":"Ramsey","year":"2017","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.pan.2020.04.018_bib4","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1097\/MPA.0000000000000896","article-title":"Local and systemic expression of immunomodulatory factors in chronic pancreatitis","volume":"46","author":"Komar","year":"2017","journal-title":"Pancreas"},{"key":"10.1016\/j.pan.2020.04.018_bib5","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1053\/j.gastro.2012.05.046","article-title":"Antioxidant therapy does not reduce pain in patients with chronic pancreatitis: the ANTICIPATE study","volume":"143","author":"Siriwardena","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1016\/j.pan.2020.04.018_bib6","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1053\/j.gastro.2008.09.028","article-title":"A\u00a0randomized controlled trial of antioxidant supplementation for pain relief in patients with chronic pancreatitis","volume":"136","author":"Bhardwaj","year":"2009","journal-title":"Gastroenterology"},{"key":"10.1016\/j.pan.2020.04.018_bib7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1476-9255-4-17","article-title":"Soy isoflavones avert chronic inflammation-induced bone loss and vascular disease","volume":"4","author":"Droke","year":"2007","journal-title":"J\u00a0Inflamm (Lond)"},{"key":"10.1016\/j.pan.2020.04.018_bib8","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.phymed.2010.07.011","article-title":"Soy isoflavones, diet and physical exercise modify serum cytokines in healthy obese postmenopausal women","volume":"18","author":"Llaneza","year":"2011","journal-title":"Phytomedicine"},{"key":"10.1016\/j.pan.2020.04.018_bib9","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1093\/ndt\/gfl169","article-title":"Positive effect of dietary soy in ESRD patients with systemic inflammation--correlation between blood levels of the soy isoflavones and the acute-phase reactants","volume":"21","author":"Fanti","year":"2006","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.pan.2020.04.018_bib10","first-page":"649","article-title":"Skeletal benefits of soy isoflavones: a review of the clinical trial and epidemiologic data","volume":"7","author":"Messina","year":"2004","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"10.1016\/j.pan.2020.04.018_bib11","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/01635589409514310","article-title":"Soy intake and cancer risk: a review of the in\u00a0vitro and in\u00a0vivo data","volume":"21","author":"Messina","year":"1994","journal-title":"Nutr Canc"},{"key":"10.1016\/j.pan.2020.04.018_bib12","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1016\/j.ejpain.2009.12.002","article-title":"Effects of soy diet on inflammation-induced primary and secondary hyperalgesia in rat","volume":"14","author":"Borzan","year":"2010","journal-title":"Eur J Pain"},{"key":"10.1016\/j.pan.2020.04.018_bib13","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1301\/nr.2003.apr.117-131","article-title":"Emerging evidence on the role of soy in reducing prostate cancer risk","volume":"61","author":"Messina","year":"2003","journal-title":"Nutr Rev"},{"key":"10.1016\/j.pan.2020.04.018_bib14","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.jnutbio.2010.04.006","article-title":"Dietary soy and tea mitigate chronic inflammation and prostate cancer via NFkappaB pathway in the Noble rat model","volume":"22","author":"Hsu","year":"2011","journal-title":"J\u00a0Nutr Biochem"},{"key":"10.1016\/j.pan.2020.04.018_bib15","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1158\/1940-6207.CAPR-14-0464","article-title":"Consumption of soy isoflavone enriched bread in men with prostate cancer is associated with reduced proinflammatory cytokines and immunosuppressive cells","volume":"8","author":"Lesinski","year":"2015","journal-title":"Canc Prev Res (Phila)"},{"key":"10.1016\/j.pan.2020.04.018_bib16","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1158\/1940-6207.CAPR-14-0465","article-title":"Isoflavone pharmacokinetics and metabolism after consumption of a standardized soy and soy-almond bread in men with asymptomatic prostate cancer","volume":"8","author":"Ahn-Jarvis","year":"2015","journal-title":"Canc Prev Res (Phila)"},{"key":"10.1016\/j.pan.2020.04.018_bib17","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1097\/MPA.0000000000000237","article-title":"American Pancreatic Association practice guidelines in chronic pancreatitis: evidence-based report on diagnostic guidelines","volume":"43","author":"Conwell","year":"2014","journal-title":"Pancreas"},{"key":"10.1016\/j.pan.2020.04.018_bib18","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1007\/s10620-017-4493-2","article-title":"Diagnosing chronic pancreatitis","volume":"62","author":"Anaizi","year":"2017","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.pan.2020.04.018_bib19","doi-asserted-by":"crossref","first-page":"3111","DOI":"10.1021\/jf304699k","article-title":"Design and selection of soy breads used for evaluating isoflavone bioavailability in clinical trials","volume":"61","author":"Ahn-Jarvis","year":"2013","journal-title":"J\u00a0Agric Food Chem"},{"key":"10.1016\/j.pan.2020.04.018_bib20","doi-asserted-by":"crossref","first-page":"2318","DOI":"10.1007\/s10620-019-05536-3","article-title":"Does the healthy eating index and mediterranean diet score identify the nutritional adequacy of dietary patterns in chronic pancreatitis?","volume":"64","author":"Roberts","year":"2019","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.pan.2020.04.018_bib21","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.clnu.2006.01.019","article-title":"ESPEN guidelines on enteral nutrition: pancreas","volume":"25","author":"Meier","year":"2006","journal-title":"Clin Nutr"},{"key":"10.1016\/j.pan.2020.04.018_bib22","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1038\/ejcn.2013.78","article-title":"Delayed gastric emptying and reduced postprandial small bowel water content of equicaloric whole meal bread versus rice meals in healthy subjects: novel MRI insights","volume":"67","author":"Marciani","year":"2013","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.pan.2020.04.018_bib23","first-page":"2786","article-title":"Isoflavones and functional foods alter the dominant intestinal microbiota in postmenopausal women","volume":"135","author":"Clavel","year":"2005","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.pan.2020.04.018_bib24","doi-asserted-by":"crossref","first-page":"7946431","DOI":"10.1155\/2018\/7946431","article-title":"Gut microbiota-immune System crosstalk and pancreatic disorders","volume":"2018","author":"Pagliari","year":"2018","journal-title":"Mediat Inflamm"},{"key":"10.1016\/j.pan.2020.04.018_bib25","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.jnutbio.2010.08.001","article-title":"Role of flavonoids in intestinal tight junction regulation","volume":"22","author":"Suzuki","year":"2011","journal-title":"J\u00a0Nutr Biochem"},{"key":"10.1016\/j.pan.2020.04.018_bib26","series-title":"Isoflavones: Chemistry, analysis, function and effects","first-page":"399","article-title":"CHAPTER 24 optimizing isoflavone-rich food delivery systems for human clinical trials","author":"Ahn-Jarvis","year":"2013"},{"key":"10.1016\/j.pan.2020.04.018_bib27","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1080\/10408390802248726","article-title":"Manipulating digestion with foods designed to change the physical characteristics of digesta","volume":"50","author":"Lentle","year":"2010","journal-title":"Crit Rev Food Sci Nutr"},{"issue":"Suppl","key":"10.1016\/j.pan.2020.04.018_bib28","doi-asserted-by":"crossref","first-page":"S46","DOI":"10.1097\/MCG.0b013e3182652096","article-title":"Role of the gut barrier in acute pancreatitis","volume":"46","author":"Capurso","year":"2012","journal-title":"J\u00a0Clin Gastroenterol"},{"key":"10.1016\/j.pan.2020.04.018_bib29","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s12026-012-8331-5","article-title":"Regulation of the immune response by soybean isoflavones","volume":"54","author":"Masilamani","year":"2012","journal-title":"Immunol Res"},{"key":"10.1016\/j.pan.2020.04.018_bib30","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3109\/09637486.2013.832170","article-title":"Intakes of total and individual flavonoids by US adults","volume":"65","author":"Bai","year":"2014","journal-title":"Int J Food Sci Nutr"},{"key":"10.1016\/j.pan.2020.04.018_bib31","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1007\/s00394-015-0942-x","article-title":"Estimated intake and major food sources of flavonoids among US adults: changes between 1999-2002 and 2007-2010 in NHANES","volume":"55","author":"Kim","year":"2016","journal-title":"Eur J Nutr"},{"key":"10.1016\/j.pan.2020.04.018_bib32","first-page":"2243","article-title":"Dietary intakes of flavonols, flavones and isoflavones by Japanese women and the inverse correlation between quercetin intake and plasma LDL cholesterol concentration","volume":"130","author":"Arai","year":"2000","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.pan.2020.04.018_bib33","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.jand.2016.10.016","article-title":"Soy isoflavone intake and sleep parameters over 5 Years among Chinese adults: longitudinal analysis from the jiangsu nutrition study","volume":"117","author":"Cao","year":"2017","journal-title":"J\u00a0Acad Nutr Diet"},{"key":"10.1016\/j.pan.2020.04.018_bib34","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1017\/S0007114515004006","article-title":"Estimation of dietary flavonoid intake and major food sources of Korean adults","volume":"115","author":"Jun","year":"2016","journal-title":"Br J Nutr"},{"key":"10.1016\/j.pan.2020.04.018_bib35","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1093\/ajcn\/54.6.1093","article-title":"Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese diet","volume":"54","author":"Adlercreutz","year":"1991","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.pan.2020.04.018_bib36","first-page":"205","article-title":"Urinary isoflavonoid excretion as a biomarker of dietary soy intake during two randomized soy trials","volume":"23","author":"Morimoto","year":"2014","journal-title":"Asia Pac J Clin Nutr"},{"key":"10.1016\/j.pan.2020.04.018_bib37","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1039\/c2fo10284f","article-title":"Impact of food matrix on isoflavone metabolism and cardiovascular biomarkers in adults with hypercholesterolemia","volume":"3","author":"Ahn-Jarvis","year":"2012","journal-title":"Food Funct"},{"key":"10.1016\/j.pan.2020.04.018_bib38","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1053\/j.gastro.2016.09.064","article-title":"Aryl hydrocarbon receptor ligands in cigarette smoke induce production of interleukin-22 to promote pancreatic fibrosis in models of chronic pancreatitis","volume":"151","author":"Xue","year":"2016","journal-title":"Gastroenterology"},{"key":"10.1016\/j.pan.2020.04.018_bib39","doi-asserted-by":"crossref","first-page":"5011","DOI":"10.1073\/pnas.1620264114","article-title":"Mathematical model of chronic pancreatitis","volume":"114","author":"Hao","year":"2017","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.pan.2020.04.018_bib40","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1007\/s00424-017-1968-0","article-title":"Biology of pancreatic stellate cells-more than just pancreatic cancer","volume":"469","author":"Ferdek","year":"2017","journal-title":"Pfl\u00fcgers Archiv"},{"key":"10.1016\/j.pan.2020.04.018_bib41","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1161\/01.CIR.0000096055.62724.C5","article-title":"Inflammatory cytokines stimulated C-reactive protein production by human coronary artery smooth muscle cells","volume":"108","author":"Calabro","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.pan.2020.04.018_bib42","doi-asserted-by":"crossref","first-page":"2044","DOI":"10.1002\/hep.22888","article-title":"Novel mechanism of C-reactive protein for enhancing mouse liver innate immunity","volume":"49","author":"Inatsu","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.pan.2020.04.018_bib43","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.pan.2016.08.002","article-title":"Acceleration of our understanding of recurrent acute and chronic pancreatitis","volume":"16","author":"Pandol","year":"2016","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2020.04.018_bib44","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1097\/MPA.0000000000001170","article-title":"PROspective evaluation of chronic pancreatitis for EpidEmiologic and translational StuDies: rationale and study design for PROCEED from the Consortium for the study of chronic pancreatitis, Diabetes, and pancreatic cancer","volume":"47","author":"Yadav","year":"2018","journal-title":"Pancreas"},{"key":"10.1016\/j.pan.2020.04.018_bib45","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1177\/1082013210387712","article-title":"Review: starch matrices and the glycemic response","volume":"17","author":"Parada","year":"2011","journal-title":"Food Sci Technol Int"}],"container-title":["Pancreatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1424390320301484?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1424390320301484?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T16:09:12Z","timestamp":1761408552000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1424390320301484"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":45,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["S1424390320301484"],"URL":"https:\/\/doi.org\/10.1016\/j.pan.2020.04.018","relation":{},"ISSN":["1424-3903"],"issn-type":[{"value":"1424-3903","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reduction of inflammation in chronic pancreatitis using a soy bread intervention: A feasibility study","name":"articletitle","label":"Article Title"},{"value":"Pancreatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pan.2020.04.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 IAP and EPC. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}