{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T21:08:49Z","timestamp":1793394529400,"version":"4.5.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pancreatology"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.pan.2021.03.006","type":"journal-article","created":{"date-parts":[[2021,3,19]],"date-time":"2021-03-19T02:36:28Z","timestamp":1616121388000},"page":"903-911","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"title":["Improved prognosis of pancreatic cancer patients with peritoneal metastasis"],"prefix":"10.1016","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0786-8166","authenticated-orcid":false,"given":"Tsuyoshi","family":"Takeda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7109-9835","authenticated-orcid":false,"given":"Takashi","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7561-5558","authenticated-orcid":false,"given":"Takafumi","family":"Mie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9746-6776","authenticated-orcid":false,"given":"Takaaki","family":"Furukawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8065-9037","authenticated-orcid":false,"given":"Yuto","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2234-1135","authenticated-orcid":false,"given":"Akiyoshi","family":"Kasuga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3604-1624","authenticated-orcid":false,"given":"Masato","family":"Matsuyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masato","family":"Ozaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0672-7214","authenticated-orcid":false,"given":"Naoki","family":"Sasahira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pan.2021.03.006_bib1","first-page":"7","article-title":"Cancer statistics","volume":"70","author":"Siegel","year":"2020","journal-title":"CA Canc J Clin"},{"key":"10.1016\/j.pan.2021.03.006_bib2","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/S1470-2045(16)00172-8","article-title":"Folfirinox for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis","volume":"17","author":"Suker","year":"2016","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.pan.2021.03.006_bib3","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1097\/MPA.0b013e3182021376","article-title":"Construction and validation of a prognostic index for patients with metastatic pancreatic adenocarcinoma","volume":"40","author":"Morizane","year":"2011","journal-title":"Pancreas"},{"key":"10.1016\/j.pan.2021.03.006_bib4","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1097\/MPA.0000000000000290","article-title":"Pancreatic cancer with malignant ascites: clinical features and outcomes","volume":"44","author":"Takahara","year":"2015","journal-title":"Pancreas"},{"key":"10.1016\/j.pan.2021.03.006_bib5","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/MPA.0b013e31825abf8c","article-title":"Incidence, prognosis, and possible treatment strategies of peritoneal carcinomatosis of pancreatic origin: a population-based study","volume":"42","author":"Thomassen","year":"2013","journal-title":"Pancreas"},{"key":"10.1016\/j.pan.2021.03.006_bib6","doi-asserted-by":"crossref","first-page":"2403","DOI":"10.1200\/JCO.1997.15.6.2403","article-title":"Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial","volume":"15","author":"Burris","year":"1997","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.pan.2021.03.006_bib7","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1200\/JCO.2006.07.9525","article-title":"Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase iii trial of the national cancer institute of Canada clinical trials group","volume":"25","author":"Moore","year":"2007","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.pan.2021.03.006_bib8","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1056\/NEJMoa1011923","article-title":"Folfirinox versus gemcitabine for metastatic pancreatic cancer","volume":"364","author":"Conroy","year":"2011","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.pan.2021.03.006_bib9","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1056\/NEJMoa1304369","article-title":"Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine","volume":"369","author":"Von Hoff","year":"2013","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.pan.2021.03.006_bib10","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/PL00011681","article-title":"Japanese classification of gastric carcinoma - 2nd English edition","volume":"1","author":"Japanese Gastric Cancer","year":"1998","journal-title":"Gastric Cancer"},{"key":"10.1016\/j.pan.2021.03.006_bib11","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1200\/JCO.2018.77.8613","article-title":"Phase iii trial comparing intraperitoneal and intravenous paclitaxel plus s-1 versus cisplatin plus s-1 in patients with gastric cancer with peritoneal metastasis: phoenix-gc trial","volume":"36","author":"Ishigami","year":"2018","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.pan.2021.03.006_bib12","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1097\/MPA.0000000000000446","article-title":"Evaluation of modified glasgow prognostic score for pancreatic cancer: a retrospective cohort study","volume":"45","author":"Imaoka","year":"2016","journal-title":"Pancreas"},{"key":"10.1016\/j.pan.2021.03.006_bib13","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.cca.2018.01.024","article-title":"Prognostic role of the neutrophil-to-lymphocyte ratio in pancreatic cancer: a meta-analysis containing 8252 patients","volume":"479","author":"Zhou","year":"2018","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.pan.2021.03.006_bib14","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/bmt.2012.244","article-title":"Investigation of the freely available easy-to-use software \u2019ezr\u2019 for medical statistics","volume":"48","author":"Kanda","year":"2013","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.pan.2021.03.006_bib15","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/(SICI)1097-0142(20000115)88:2<358::AID-CNCR16>3.0.CO;2-O","article-title":"Peritoneal carcinomatosis from non-gynecologic malignancies: results of the evocape 1 multicentric prospective study","volume":"88","author":"Sadeghi","year":"2000","journal-title":"Cancer"},{"key":"10.1016\/j.pan.2021.03.006_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1443-1661.2012.01319.x","article-title":"Japanese multicenter estimation of wallflex duodenal stent for unresectable malignant gastric outlet obstruction","volume":"25","author":"Sasaki","year":"2013","journal-title":"Dig Endosc"},{"key":"10.1016\/j.pan.2021.03.006_bib17","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1200\/JOP.2017.022210","article-title":"Management of malignant bowel obstruction associated with gi cancers","volume":"13","author":"Franke","year":"2017","journal-title":"J\u00a0Oncol Pract"},{"key":"10.1016\/j.pan.2021.03.006_bib18","series-title":"Feasibility, efficacy, and safety of cell-free and concentrated ascites reinfusion therapy (km-cart) for malignant ascites","author":"Matsusaki","year":"2020"},{"key":"10.1016\/j.pan.2021.03.006_bib19","first-page":"201","article-title":"[effect of tolvaptan on ascites due to malignancy]","volume":"42","author":"Mitsuhashi","year":"2015","journal-title":"Gan To Kagaku Ryoho"},{"key":"10.1016\/j.pan.2021.03.006_bib20","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1093\/jjco\/hyaa196","article-title":"Efficacy and safety of tolvaptan in patients with malignant ascites: a phase 2, multicenter, open-label, dose-escalation study","volume":"51","author":"Kudo","year":"2021","journal-title":"Jpn J Clin Oncol"},{"key":"10.1016\/j.pan.2021.03.006_bib21","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1111\/j.1440-1746.2012.07241.x","article-title":"Role of intervention for biliary and gastric\/intestinal obstruction in gastric cancer with peritoneal metastasis","volume":"27","author":"Nakai","year":"2012","journal-title":"J\u00a0Gastroenterol Hepatol"},{"key":"10.1016\/j.pan.2021.03.006_bib22","first-page":"271","article-title":"Improvement of treatment outcomes for metastatic pancreatic cancer: a real-world data analysis","volume":"33","author":"Sasaki","year":"2019","journal-title":"In\u00a0vivo (Athens, Greece)"},{"key":"10.1016\/j.pan.2021.03.006_bib23","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1056\/NEJMoa052985","article-title":"Intraperitoneal cisplatin and paclitaxel in ovarian cancer","volume":"354","author":"Armstrong","year":"2006","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.pan.2021.03.006_bib24","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s10637-020-00982-7","article-title":"A\u00a0phase i study of intraperitoneal paclitaxel combined with gemcitabine plus nab-paclitaxel for pancreatic cancer with peritoneal metastasis","volume":"39","author":"Takahara","year":"2021","journal-title":"Invest N Drugs"},{"key":"10.1016\/j.pan.2021.03.006_bib25","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1007\/s10637-016-0369-0","article-title":"Intravenous and intraperitoneal paclitaxel with s-1 for treatment of refractory pancreatic cancer with malignant ascites","volume":"34","author":"Takahara","year":"2016","journal-title":"Invest N Drugs"},{"key":"10.1016\/j.pan.2021.03.006_bib26","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1097\/SLA.0000000000001705","article-title":"Multicenter phase ii study of intravenous and intraperitoneal paclitaxel with s-1 for pancreatic ductal adenocarcinoma patients with peritoneal metastasis","volume":"265","author":"Satoi","year":"2017","journal-title":"Ann Surg"}],"container-title":["Pancreatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1424390321001009?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1424390321001009?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T16:13:59Z","timestamp":1761408839000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1424390321001009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["S1424390321001009"],"URL":"https:\/\/doi.org\/10.1016\/j.pan.2021.03.006","relation":{},"ISSN":["1424-3903"],"issn-type":[{"value":"1424-3903","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Improved prognosis of pancreatic cancer patients with peritoneal metastasis","name":"articletitle","label":"Article Title"},{"value":"Pancreatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pan.2021.03.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 IAP and EPC. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}