{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T01:14:56Z","timestamp":1775092496615,"version":"3.50.1"},"reference-count":32,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["BO 5659\/1-1"],"award-info":[{"award-number":["BO 5659\/1-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pancreatology"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.pan.2021.03.009","type":"journal-article","created":{"date-parts":[[2021,3,20]],"date-time":"2021-03-20T01:17:01Z","timestamp":1616203021000},"page":"957-964","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["A simple preoperative stratification tool predicting the risk of postoperative pancreatic fistula after pancreatoduodenectomy"],"prefix":"10.1016","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0435-5189","authenticated-orcid":false,"given":"Hryhoriy","family":"Lapshyn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8769-744X","authenticated-orcid":false,"given":"Natalie","family":"Petruch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5405-9716","authenticated-orcid":false,"given":"Michael","family":"Thomaschewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6973-0824","authenticated-orcid":false,"given":"Stefan","family":"Sondermann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"May","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Frohneberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekaterina","family":"Petrova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergii","family":"Zemskov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim C.","family":"Honselmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00fcdiger","family":"Braun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Keck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich F.","family":"Wellner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louisa","family":"Bolm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.pan.2021.03.009_bib1","first-page":"241","article-title":"Pancreatic cancer: state-of-the-art care","volume":"50","author":"Lillemoe","year":"2000","journal-title":"Ca - Cancer J Clin"},{"key":"10.1016\/j.pan.2021.03.009_bib2","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1097\/SLA.0000000000001660","article-title":"Minimally invasive versus open pancreatoduodenectomy: systematic review and meta-analysis of comparative cohort and registry studies","volume":"264","author":"de Rooij","year":"2016","journal-title":"Ann Surg"},{"key":"10.1016\/j.pan.2021.03.009_bib3","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1111\/j.1477-2574.2010.00216.x","article-title":"Pancreatectomy risk calculator: an ACS-NSQIP resource","volume":"12","author":"Parikh","year":"2010","journal-title":"Hpb"},{"key":"10.1016\/j.pan.2021.03.009_bib4","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1245\/s10434-006-9131-8","article-title":"Pancreatic resection for M1 pancreatic ductal adenocarcinoma","volume":"14","author":"Shrikhande","year":"2007","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.pan.2021.03.009_bib5","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/602478","article-title":"Pancreatic fistula after pancreatectomy: definitions, risk factors, preventive measures, and management\u2014review","volume":"2012","author":"Oneil Machado","year":"2012","journal-title":"International journal of surgical oncology"},{"key":"10.1016\/j.pan.2021.03.009_bib6","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1097\/01.sla.0000189124.47589.6d","article-title":"Reconstruction by pancreaticojejunostomy versus pancreaticogastrostomy following pancreatectomy: results of a comparative study","volume":"242","author":"Bassi","year":"2005","journal-title":"Ann Surg"},{"key":"10.1016\/j.pan.2021.03.009_bib7","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.surg.2016.11.014","article-title":"The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years after","volume":"161","author":"Bassi","year":"2017","journal-title":"Surgery"},{"key":"10.1016\/j.pan.2021.03.009_bib8","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/hpb.12063","article-title":"Pancreatic fistula after a pancreaticoduodenectomy for ductal adenocarcinoma and its association with morbidity: a multicentre study of the French Surgical Association","volume":"16","author":"Addeo","year":"2014","journal-title":"HPB"},{"key":"10.1016\/j.pan.2021.03.009_bib9","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.pan.2018.11.008","article-title":"Risk stratification for postoperative pancreatic fistula using the pancreatic surgery registry StuDoQ|Pancreas of the German Society for General and Visceral Surgery","volume":"19","author":"Petrova","year":"2019","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2021.03.009_bib10","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1007\/s11605-008-0763-9","article-title":"Reduced postoperative pancreatic fistula rate after pancreatogastrostomy versus pancreaticojejunostomy","volume":"13","author":"Wellner","year":"2009","journal-title":"J\u00a0Gastrointest Surg"},{"key":"10.1016\/j.pan.2021.03.009_bib11","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1007\/s11605-012-1940-4","article-title":"Randomized controlled single-center trial comparing pancreatogastrostomy versus pancreaticojejunostomy after partial pancreatoduodenectomy","volume":"16","author":"Wellner","year":"2012","journal-title":"J\u00a0Gastrointest Surg"},{"key":"10.1016\/j.pan.2021.03.009_bib12","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/j.pan.2019.05.457","article-title":"Perioperative hydrocortisone treatment reduces postoperative pancreatic fistula rate after open distal pancreatectomy. A randomized placebo-controlled trial","volume":"19","author":"Antila","year":"2019","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2021.03.009_bib13","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.surg.2007.05.005","article-title":"Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS)","volume":"142","author":"Wente","year":"2007","journal-title":"Surgery"},{"key":"10.1016\/j.pan.2021.03.009_bib14","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.surg.2007.02.001","article-title":"Postpancreatectomy hemorrhage (PPH)\u2013an international study group of pancreatic surgery (ISGPS) definition","volume":"142","author":"Wente","year":"2007","journal-title":"Surgery"},{"key":"10.1016\/j.pan.2021.03.009_bib15","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.ejca.2008.10.026","article-title":"New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)","volume":"45","author":"Eisenhauer","year":"2009","journal-title":"Eur J Canc"},{"key":"10.1016\/j.pan.2021.03.009_bib16","first-page":"1","article-title":"Regularization paths for generalized linear models via coordinate descent","volume":"33","author":"Friedman","year":"2010","journal-title":"J\u00a0Stat Software"},{"key":"10.1016\/j.pan.2021.03.009_bib17","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1080\/10618600.1996.10474713","article-title":"A\u00a0language for data analysis and graphics","volume":"5","author":"Ihaka","year":"1996","journal-title":"J\u00a0Comput Graph Stat"},{"key":"10.1016\/j.pan.2021.03.009_bib18","article-title":"Effect of preoperative biliary drainage on complications following pancreatoduodenectomy: a meta-analysis","volume":"94","author":"Chen","year":"2015","journal-title":"Medicine"},{"key":"10.1016\/j.pan.2021.03.009_bib19","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1007\/s11605-014-2725-8","article-title":"Perioperative and long-term outcome after standard pancreaticoduodenectomy, additional portal vein and multivisceral resection for pancreatic head cancer","volume":"19","author":"Kulemann","year":"2015","journal-title":"J\u00a0Gastrointest Surg"},{"key":"10.1016\/j.pan.2021.03.009_bib20","series-title":"Quality indicators for pancreatic surgery: scientific derivation and clinical relevance. Der Chirurg","author":"Wellner","year":"2017"},{"key":"10.1016\/j.pan.2021.03.009_bib21","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1097\/SLA.0000000000001240","article-title":"Pancreatogastrostomy versus pancreatojejunostomy for RECOnstruction after PANCreatoduodenectomy (RECOPANC, DRKS 00000767): perioperative and long-term results of a multicenter randomized controlled trial","volume":"263","author":"Keck","year":"2016","journal-title":"Ann Surg"},{"key":"10.1016\/j.pan.2021.03.009_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jamcollsurg.2012.09.002","article-title":"A\u00a0prospectively validated clinical risk score accurately predicts pancreatic fistula after pancreatoduodenectomy","volume":"216","author":"Callery","year":"2013","journal-title":"J\u00a0Am Coll Surg"},{"key":"10.1016\/j.pan.2021.03.009_bib23","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1001\/archsurg.137.9.1044","article-title":"Selection of pancreaticojejunostomy techniques according to pancreatic texture and duct size","volume":"137","author":"Suzuki","year":"2002","journal-title":"Arch Surg"},{"key":"10.1016\/j.pan.2021.03.009_bib24","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1007\/s11605-017-3356-7","article-title":"In patients with a soft pancreas, a thick parenchyma, a small duct, and fatty infiltration are significant risks for pancreatic fistula after pancreaticoduodenectomy","volume":"21","author":"Sugimoto","year":"2017","journal-title":"J\u00a0Gastrointest Surg"},{"key":"10.1016\/j.pan.2021.03.009_bib25","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1007\/s00595-016-1364-y","article-title":"A\u00a0comparative study on the complications of conventional and end-to-side inserting pancreatojejunostomy after pancreaticoduodenectomy","volume":"47","author":"Hashimoto","year":"2017","journal-title":"Surg Today"},{"key":"10.1016\/j.pan.2021.03.009_bib26","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.jamcollsurg.2017.01.054","article-title":"Using the NSQIP pancreatic demonstration project to derive a modified fistula risk score for preoperative risk stratification in patients undergoing pancreaticoduodenectomy","volume":"224","author":"Kantor","year":"2017","journal-title":"J\u00a0Am Coll Surg"},{"key":"10.1016\/j.pan.2021.03.009_bib27","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1097\/SLA.0000000000002620","article-title":"Alternative fistula risk score for pancreatoduodenectomy (a-FRS): design and international external validation","volume":"269","author":"Mungroop","year":"2019","journal-title":"Ann Surg"},{"key":"10.1016\/j.pan.2021.03.009_bib28","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.pan.2013.04.322","article-title":"Pre-operative prediction of pancreatic fistula: is it possible?","volume":"13","author":"Roberts","year":"2013","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2021.03.009_bib29","doi-asserted-by":"crossref","first-page":"103096","DOI":"10.1016\/j.ebiom.2020.103096","article-title":"Computed tomography-adjusted fistula risk score for predicting clinically relevant postoperative pancreatic fistula after pancreatoduodenectomy: training and external validation of model upgrade","volume":"62","author":"Shi","year":"2020","journal-title":"EBioMedicine"},{"key":"10.1016\/j.pan.2021.03.009_bib30","doi-asserted-by":"crossref","first-page":"2747","DOI":"10.1007\/s00268-011-1253-x","article-title":"A\u00a0preoperative predictive scoring system for postoperative pancreatic fistula after pancreaticoduodenectomy","volume":"35","author":"Yamamoto","year":"2011","journal-title":"World J Surg"},{"key":"10.1016\/j.pan.2021.03.009_bib31","doi-asserted-by":"crossref","first-page":"e1152","DOI":"10.1097\/MD.0000000000001152","article-title":"Preoperative computed tomography to predict and stratify the risk of severe pancreatic fistula after pancreatoduodenectomy","volume":"94","author":"Sandini","year":"2015","journal-title":"Medicine (Baltim)"},{"key":"10.1016\/j.pan.2021.03.009_bib32","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1056\/NEJMoa1313688","article-title":"Pasireotide for postoperative pancreatic fistula","volume":"370","author":"Allen","year":"2014","journal-title":"N\u00a0Engl J Med"}],"container-title":["Pancreatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1424390321001034?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1424390321001034?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T16:14:22Z","timestamp":1761408862000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1424390321001034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["S1424390321001034"],"URL":"https:\/\/doi.org\/10.1016\/j.pan.2021.03.009","relation":{},"ISSN":["1424-3903"],"issn-type":[{"value":"1424-3903","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A simple preoperative stratification tool predicting the risk of postoperative pancreatic fistula after pancreatoduodenectomy","name":"articletitle","label":"Article Title"},{"value":"Pancreatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pan.2021.03.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 IAP and EPC. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}