{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T11:36:35Z","timestamp":1774611395706,"version":"3.50.1"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pancreatology"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.pan.2023.01.002","type":"journal-article","created":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T11:55:11Z","timestamp":1672746911000},"page":"151-157","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Utility of Fecal Elastase-1 to diagnose severe exocrine insufficiency in chronic pancreatitis: Real world experience"],"prefix":"10.1016","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3459-8448","authenticated-orcid":false,"given":"Srikanth","family":"Gopi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8912-2949","authenticated-orcid":false,"given":"Namrata","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6088-6064","authenticated-orcid":false,"given":"Jatin","family":"Yegurla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5192-6901","authenticated-orcid":false,"given":"Mohammad","family":"Tabish","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2053-2069","authenticated-orcid":false,"given":"Samagra","family":"Agarwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8434-3884","authenticated-orcid":false,"given":"Sumaira","family":"Qamar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepak","family":"Gunjan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3921-6752","authenticated-orcid":false,"given":"Anoop","family":"Saraya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.pan.2023.01.002_bib1","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1007\/s10620-017-4524-z","article-title":"Potential for screening for pancreatic exocrine insufficiency using the fecal elastase-1 test","volume":"62","author":"Dom\u00ednguez-Mu\u00f1oz","year":"2017","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.pan.2023.01.002_bib2","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1007\/BF01308149","article-title":"Pancreolauryl test. Evaluation of a tubeless pancreatic function test in comparison with other indirect and direct tests for exocrine pancreatic function","volume":"28","author":"Lankisch","year":"1983","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.pan.2023.01.002_bib3","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/s11894-007-0005-4","article-title":"Pancreatic enzyme therapy for pancreatic exocrine insufficiency","volume":"9","author":"Dom\u00ednguez-Mu\u00f1oz","year":"2007","journal-title":"Curr Gastroenterol Rep"},{"key":"10.1016\/j.pan.2023.01.002_bib4","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1016\/j.cgh.2018.01.027","article-title":"Diagnostic performance of measurement of fecal elastase-1 in detection of exocrine pancreatic insufficiency: systematic review and meta-analysis","volume":"16","author":"Vanga","year":"2018","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.pan.2023.01.002_bib5","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1177\/2050640616684695","article-title":"United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis (HaPanEU)","volume":"5","author":"L\u00f6hr","year":"2017","journal-title":"United European Gastroenterol J"},{"key":"10.1016\/j.pan.2023.01.002_bib6","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1136\/gut.42.4.551","article-title":"Faecal elastase 1: not helpful in diagnosing chronic pancreatitis associated with mild to moderate exocrine pancreatic insufficiency","volume":"42","author":"Lankisch","year":"1998","journal-title":"Gut"},{"key":"10.1016\/j.pan.2023.01.002_bib7","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1097\/00006676-199610000-00002","article-title":"Fecal pancreatic elastase 1 is inaccurate in the diagnosis of chronic pancreatitis","volume":"13","author":"Amann","year":"1996","journal-title":"Pancreas"},{"key":"10.1016\/j.pan.2023.01.002_bib8","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.pan.2012.11.307","article-title":"Fecal elastase-1 is useful in the detection of steatorrhea in patients with pancreatic diseases but not after pancreatic resection","volume":"13","author":"Benini","year":"2013","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2023.01.002_bib9","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.pan.2020.02.004","article-title":"Natural course of chronic pancreatitis and predictors of its progression","volume":"20","author":"Agarwal","year":"2020","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2023.01.002_bib10","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1097\/MPA.0000000000001473","article-title":"Natural course and treatment of pancreatic exocrine insufficiency in a nationwide cohort of chronic pancreatitis","volume":"49","author":"Kempeneers","year":"2020","journal-title":"Pancreas"},{"key":"10.1016\/j.pan.2023.01.002_bib11","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1097\/MCG.0000000000001178","article-title":"Antioxidants for pancreatic functions in chronic pancreatitis: a double-blind randomized placebo-controlled pilot study","volume":"54","author":"Singh","year":"2020","journal-title":"J\u00a0Clin Gastroenterol"},{"key":"10.1016\/j.pan.2023.01.002_bib12","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.pan.2020.03.014","volume":"20","author":"P","year":"2020","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2023.01.002_bib13","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.1001\/jama.2019.19411","article-title":"Diagnosis and management of chronic pancreatitis: a review","volume":"322","author":"Singh","year":"2019","journal-title":"JAMA, J Am Med Assoc"},{"issue":"1","key":"10.1016\/j.pan.2023.01.002_bib14","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1023\/A:1026691209094","article-title":"Fecal elastase 1 determination in chronic pancreatitis","volume":"44","author":"Gullo","year":"1999","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.pan.2023.01.002_bib15","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1136\/gut.39.4.580","article-title":"Faecal elastase 1: a novel, highly sensitive, and specific tubeless pancreatic function test","volume":"39","author":"L\u00f6ser","year":"1996","journal-title":"Gut"},{"key":"10.1016\/j.pan.2023.01.002_bib16","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1007\/s00535-006-1884-0","article-title":"Fecal pancreatic elastase: a reproducible marker for severe exocrine pancreatic insufficiency","volume":"41","author":"Naruse","year":"2006","journal-title":"J\u00a0Gastroenterol"},{"key":"10.1016\/j.pan.2023.01.002_bib17","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1097\/MOG.0000000000000459","article-title":"Diagnosis and treatment of pancreatic exocrine insufficiency","volume":"34","author":"Dominguez-Mu\u00f1oz","year":"2018","journal-title":"Curr Opin Gastroenterol"},{"key":"10.1016\/j.pan.2023.01.002_bib18","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.pan.2021.11.005","article-title":"Staging exocrine pancreatic dysfunction","volume":"22","author":"Khan","year":"2022","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2023.01.002_bib19","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.pan.2022.02.004","article-title":"Malnutrition by GLIM criteria in chronic pancreatitis: prevalence, predictors, and its impact on quality of life","volume":"22","author":"Gopi","year":"2022","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2023.01.002_bib20","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.pan.2022.02.003","article-title":"Exocrine pancreas insufficiency in chronic pancreatitis \u2013 risk factors and associations with complications. A multicentre study of 1869 patients","volume":"22","author":"Erchinger","year":"2022","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2023.01.002_bib21","doi-asserted-by":"crossref","DOI":"10.14309\/ctg.0000000000000072","article-title":"Factors that affect prevalence of small intestinal bacterial overgrowth in chronic pancreatitis: a systematic review, meta-analysis, and meta-regression","volume":"10","author":"el Kurdi","year":"2019","journal-title":"Clin Transl Gastroenterol"},{"key":"10.1016\/j.pan.2023.01.002_bib22","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1177\/0884533614528361","article-title":"The prevalence of malnutrition and fat-soluble vitamin deficiencies in chronic pancreatitis","volume":"29","author":"Duggan","year":"2014","journal-title":"Nutr Clin Pract"},{"key":"10.1016\/j.pan.2023.01.002_bib23","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.pan.2013.02.008","article-title":"The prevalence of fat-soluble vitamin deficiencies and a decreased bone mass in patients with chronic pancreatitis","volume":"13","author":"Sikkens","year":"2013","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2023.01.002_bib24","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1007\/BF02087550","article-title":"Marks IN. Fat-soluble vitamin concentration in chronic alcohol-induced pancreatitis. Relationship with steatorrhea","volume":"39","author":"Marotta","year":"1994","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.pan.2023.01.002_bib25","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.pan.2015.07.001","article-title":"Clinical, anthropometric and laboratory nutritional markers of pancreatic exocrine insufficiency: prevalence and diagnostic use","volume":"15","author":"Lindkvist","year":"2015","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2023.01.002_bib26","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1007\/BF02088241","article-title":"Deficiency in antioxidant factors in patients with alcohol-related chronic pancreatitis","volume":"41","author":"van Gossum","year":"1996","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.pan.2023.01.002_bib27","first-page":"286","article-title":"Faecal elastase-I: helpful in analysing steatorrhoea?","volume":"62","author":"Symersky","year":"2004","journal-title":"Neth J Med"},{"key":"10.1016\/j.pan.2023.01.002_bib28","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.pan.2012.11.307","article-title":"Fecal elastase-1 is useful in the detection of steatorrhea in patients with pancreatic diseases but not after pancreatic resection","volume":"13","author":"Benini","year":"2013","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2023.01.002_bib29","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/s12664-016-0714-4","article-title":"Pancreatic exocrine insufficiency: comparing fecal elastase 1 with 72-h stool for fecal fat estimation","volume":"35","author":"Chowdhury","year":"2016","journal-title":"Indian J Gastroenterol"}],"container-title":["Pancreatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1424390323000261?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1424390323000261?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T16:18:17Z","timestamp":1761409097000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1424390323000261"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["S1424390323000261"],"URL":"https:\/\/doi.org\/10.1016\/j.pan.2023.01.002","relation":{},"ISSN":["1424-3903"],"issn-type":[{"value":"1424-3903","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Utility of Fecal Elastase-1 to diagnose severe exocrine insufficiency in chronic pancreatitis: Real world experience","name":"articletitle","label":"Article Title"},{"value":"Pancreatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pan.2023.01.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Published by Elsevier B.V. on behalf of IAP and EPC.","name":"copyright","label":"Copyright"}]}}