{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:36:18Z","timestamp":1787067378281,"version":"build-2736575974"},"reference-count":37,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100008048","name":"Nanjing University","doi-asserted-by":"publisher","award":["97104"],"award-info":[{"award-number":["97104"]}],"id":[{"id":"10.13039\/501100008048","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pancreatology"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.pan.2026.01.073","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T15:55:09Z","timestamp":1769442909000},"page":"231-237","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Accelerated focused open necrosectomy-based step-cross versus conventional step-up approach in infected necrotizing pancreatitis"],"prefix":"10.1016","volume":"26","author":[{"given":"Shuai","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wutao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaiming","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minchun","family":"Bu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Ke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihui","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiqin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pan.2026.01.073_bib1","doi-asserted-by":"crossref","first-page":"419","DOI":"10.14309\/ajg.0000000000002645","article-title":"American college of gastroenterology guidelines: management of acute pancreatitis","volume":"119","author":"Tenner","year":"2024","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.pan.2026.01.073_bib2","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1053\/j.gastro.2024.02.052","article-title":"Diagnosis and management of acute pancreatitis","volume":"167","author":"Trikudanathan","year":"2024","journal-title":"Gastroenterology"},{"key":"10.1016\/j.pan.2026.01.073_bib3","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/S0140-6736(20)31310-6","article-title":"Acute pancreatitis","volume":"396","author":"Boxhoorn","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.pan.2026.01.073_bib4","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1001\/jama.2020.20317","article-title":"Acute pancreatitis: a review","volume":"325","author":"Mederos","year":"2021","journal-title":"JAMA"},{"key":"10.1016\/j.pan.2026.01.073_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejim.2024.10.030","article-title":"Practical management of severe acute pancreatitis","volume":"133","author":"Hamesch","year":"2025","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.pan.2026.01.073_bib6","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1097\/SLA.0000000000006001","article-title":"Long-term outcome of immediate versus postponed intervention in patients with infected necrotizing pancreatitis (pointer): Multicenter randomized trial","volume":"279","author":"Van Veldhuisen","year":"2024","journal-title":"Ann Surg"},{"key":"10.1016\/j.pan.2026.01.073_bib7","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1001\/jamasurg.2022.5695","article-title":"Contemporary surgical management of pancreatic necrosis","volume":"158","author":"Maurer","year":"2023","journal-title":"JAMA Surg"},{"key":"10.1016\/j.pan.2026.01.073_bib8","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1056\/NEJMoa0908821","article-title":"A step-up approach or open necrosectomy for necrotizing pancreatitis","volume":"362","author":"van Santvoort","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pan.2026.01.073_bib9","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.pan.2013.07.063","article-title":"Iap\/apa evidence-based guidelines for the management of acute pancreatitis","volume":"13","year":"2013","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2026.01.073_bib10","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1053\/j.gastro.2019.07.064","article-title":"American gastroenterological association clinical practice update: management of pancreatic necrosis","volume":"158","author":"Baron","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1016\/j.pan.2026.01.073_bib11","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1053\/j.gastro.2022.05.015","article-title":"Endoscopic versus surgical step-up approach for infected necrotizing pancreatitis (extension): Long-Term follow-up of a randomized trial","volume":"163","author":"Onnekink","year":"2022","journal-title":"Gastroenterology"},{"key":"10.1016\/j.pan.2026.01.073_bib12","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.jamcollsurg.2020.01.038","article-title":"Improved mortality in necrotizing pancreatitis with a multidisciplinary minimally invasive step-up approach: Comparison with a modern open necrosectomy cohort","volume":"230","author":"Luckhurst","year":"2020","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.pan.2026.01.073_bib13","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.pan.2020.05.024","article-title":"Operative pancreatic debridement: contemporary outcomes in changing times","volume":"20","author":"Maatman","year":"2020","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2026.01.073_bib14","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1016\/j.surg.2024.01.021","article-title":"Is contemporary open pancreatic necrosectomy still useful in the minimally invasive era?","volume":"175","author":"Ning","year":"2024","journal-title":"Surgery"},{"key":"10.1016\/j.pan.2026.01.073_bib15","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s13017-020-00326-z","article-title":"Open necrosectomy is feasible as a last resort in selected cases with infected pancreatic necrosis: a case series and systematic literature review","volume":"15","author":"Sgaramella","year":"2020","journal-title":"World J Emerg Surg"},{"key":"10.1016\/j.pan.2026.01.073_bib16","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1097\/SLA.0b013e318269d25d","article-title":"Predictors of surgery in patients with severe acute pancreatitis managed by the step-up approach","volume":"257","author":"Babu","year":"2013","journal-title":"Ann Surg"},{"key":"10.1016\/j.pan.2026.01.073_bib17","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1007\/s00535-023-01994-9","article-title":"Does early intervention for infected pancreatic necrosis lead to better clinical outcomes compared to delayed intervention?","volume":"58","author":"Sakai","year":"2023","journal-title":"J Gastroenterol"},{"key":"10.1016\/j.pan.2026.01.073_bib18","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1097\/JS9.0000000000000415","article-title":"Nomogram development and validation for predicting minimally invasive step-up approach failure in infected necrotizing pancreatitis patients: a retrospective cohort study","volume":"109","author":"Li","year":"2023","journal-title":"Int J Surg"},{"key":"10.1016\/j.pan.2026.01.073_bib19","first-page":"666","article-title":"Damage control surgery: old concepts and new indications","volume":"29","author":"Chung","year":"2023","journal-title":"Curr Opin Crit Care"},{"key":"10.1016\/j.pan.2026.01.073_bib20","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1111\/hpb.12004","article-title":"Focused open necrosectomy in necrotizing pancreatitis","volume":"15","author":"Pupelis","year":"2013","journal-title":"HPB (Oxford)"},{"key":"10.1016\/j.pan.2026.01.073_bib21","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1097\/CM9.0000000000001877","article-title":"From \"step-up\" to \"step-jump\": a leap-forward intervention for infected necrotizing pancreatitis","volume":"135","author":"Huang","year":"2021","journal-title":"Chin Med J (Engl)"},{"key":"10.1016\/j.pan.2026.01.073_bib22","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1136\/gutjnl-2012-302779","article-title":"Classification of acute pancreatitis--2012: revision of the atlanta classification and definitions by international consensus","volume":"62","author":"Banks","year":"2013","journal-title":"Gut"},{"key":"10.1016\/j.pan.2026.01.073_bib23","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","article-title":"The strengthening the reporting of observational studies in epidemiology (strobe) statement: guidelines for reporting observational studies","volume":"370","author":"von Elm","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.pan.2026.01.073_bib24","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1001\/jama.2016.0287","article-title":"The third international consensus definitions for sepsis and septic shock (sepsis-3)","volume":"315","author":"Singer","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.pan.2026.01.073_bib25","article-title":"Early spontaneous abdominal bleeding is associated with poor outcome in moderate to severe acute pancreatitis patients: a propensity matched study","volume":"7","author":"Chen","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.pan.2026.01.073_bib26","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.pan.2019.11.010","article-title":"Site and size of extrapancreatic necrosis are associated with clinical outcomes in patients with acute necrotizing pancreatitis","volume":"20","author":"Gupta","year":"2020","journal-title":"Pancreatology"},{"key":"10.1016\/j.pan.2026.01.073_bib27","doi-asserted-by":"crossref","first-page":"4603","DOI":"10.1007\/s00464-017-5522-0","article-title":"The effect of a novel minimally invasive strategy for infected necrotizing pancreatitis","volume":"31","author":"Tong","year":"2017","journal-title":"Surg Endosc"},{"key":"10.1016\/j.pan.2026.01.073_bib28","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/0895-4356(95)00510-2","article-title":"Importance of events per independent variable in proportional hazards analysis. I. Background, goals, and general strategy","volume":"48","author":"Concato","year":"1995","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.pan.2026.01.073_bib29","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1056\/NEJMra2403213","article-title":"Sepsis and septic shock","volume":"391","author":"Meyer","year":"2024","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pan.2026.01.073_bib30","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s13054-022-03901-9","article-title":"Adverse effects of delayed antimicrobial treatment and surgical source control in adults with sepsis: results of a planned secondary analysis of a cluster-randomized controlled trial","volume":"26","author":"Ruddel","year":"2022","journal-title":"Crit Care"},{"key":"10.1016\/j.pan.2026.01.073_bib31","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1056\/NEJMoa1703058","article-title":"Time to treatment and mortality during mandated emergency care for sepsis","volume":"376","author":"Seymour","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pan.2026.01.073_bib32","first-page":"225","article-title":"Is minimally invasive surgical treatment justified for severe acute necrotizing pancreatitis patients with dysfunction of two or more organ systems?","volume":"12","author":"Sileikis","year":"2017","journal-title":"Wideochir Inne Tech Maloinwazyjne"},{"key":"10.1016\/j.pan.2026.01.073_bib33","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1159\/000501076","article-title":"One-step verse step-up laparoscopic-assisted necrosectomy for infected pancreatic necrosis","volume":"37","author":"Cao","year":"2020","journal-title":"Dig Surg"},{"key":"10.1016\/j.pan.2026.01.073_bib34","doi-asserted-by":"crossref","first-page":"274","DOI":"10.5847\/wjem.j.1920-8642.2022.058","article-title":"One-step laparoscopic pancreatic necrosectomy verse surgical step-up approach for infected pancreatic necrosis: a case-control study","volume":"13","author":"Han","year":"2022","journal-title":"World J Emerg Med"},{"key":"10.1016\/j.pan.2026.01.073_bib35","doi-asserted-by":"crossref","first-page":"6005","DOI":"10.2147\/JIR.S461740","article-title":"Effect of the step-jump approach in infected pancreatic necrosis: a propensity score-matched study","volume":"17","author":"Bai","year":"2024","journal-title":"J Inflamm Res"},{"key":"10.1016\/j.pan.2026.01.073_bib36","doi-asserted-by":"crossref","first-page":"e573","DOI":"10.1097\/MPA.0000000000002334","article-title":"The potential clinical benefits of direct surgical transgastric pancreatic necrosectomy for patients with infected necrotizing pancreatitis","volume":"53","author":"Timmerhuis","year":"2024","journal-title":"Pancreas"},{"key":"10.1016\/j.pan.2026.01.073_bib37","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1097\/SLA.0000000000004997","article-title":"Outcomes in endoscopic and operative transgastric pancreatic debridement","volume":"274","author":"Maatman","year":"2021","journal-title":"Ann Surg"}],"container-title":["Pancreatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1424390326000888?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1424390326000888?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T07:24:09Z","timestamp":1773991449000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1424390326000888"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S1424390326000888"],"URL":"https:\/\/doi.org\/10.1016\/j.pan.2026.01.073","relation":{},"ISSN":["1424-3903"],"issn-type":[{"value":"1424-3903","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Accelerated focused open necrosectomy-based step-cross versus conventional step-up approach in infected necrotizing pancreatitis","name":"articletitle","label":"Article Title"},{"value":"Pancreatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pan.2026.01.073","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 IAP and EPC. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}