{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T21:21:12Z","timestamp":1788470472655,"version":"build-2803163510"},"reference-count":39,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100016714","name":"University of Sharjah","doi-asserted-by":"publisher","award":["25010901180"],"award-info":[{"award-number":["25010901180"]}],"id":[{"id":"10.13039\/100016714","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pancreatology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.pan.2026.07.001","type":"journal-article","created":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T06:48:17Z","timestamp":1783147697000},"page":"826-834","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Neuromuscular biomarkers are associated with sarcopenia and physical performance in chronic pancreatitis: An integrative biomarker profiling study"],"prefix":"10.1016","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8485-7172","authenticated-orcid":false,"given":"Rizwan","family":"Qaisar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taimur","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Firdos","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6288-0686","authenticated-orcid":false,"given":"Asima","family":"Karim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.pan.2026.07.001_bib1","doi-asserted-by":"crossref","DOI":"10.3390\/nu17050870","article-title":"Prevalence and risk of sarcopenia in patients with chronic pancreatitis: systematic review and meta-analysis","volume":"17","author":"Khurmatullina","year":"2025","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.pan.2026.07.001_bib2","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s10238-025-02023-0","article-title":"Global, regional, and national burden and future projections of pancreatitis: a joinpoint, APC, and ARIMA modeling analysis","volume":"26","author":"Zhang","year":"2026","journal-title":"Clin Exp Med"},{"issue":"4","key":"10.1016\/j.pan.2026.07.001_bib3","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s11894-022-00837-6","article-title":"Sarcopenia in chronic pancreatitis - prevalence, diagnosis, mechanisms and potential therapies","volume":"24","author":"Fasullo","year":"2022","journal-title":"Curr Gastroenterol Rep"},{"issue":"18","key":"10.1016\/j.pan.2026.07.001_bib4","doi-asserted-by":"crossref","DOI":"10.3346\/jkms.2022.37.e146","article-title":"A review of sarcopenia pathophysiology, diagnosis, treatment and future direction","volume":"37","author":"Cho","year":"2022","journal-title":"J Kor Med Sci"},{"issue":"4","key":"10.1016\/j.pan.2026.07.001_bib5","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1093\/ageing\/afz046","article-title":"Sarcopenia: revised European consensus on definition and diagnosis","volume":"48","author":"Cruz-Jentoft","year":"2019","journal-title":"Age Ageing"},{"key":"10.1016\/j.pan.2026.07.001_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2023.101966","article-title":"Neuromuscular junction transmission failure in aging and sarcopenia: the nexus of the neurological and muscular systems","volume":"89","author":"Arnold","year":"2023","journal-title":"Ageing Res Rev"},{"key":"10.1016\/j.pan.2026.07.001_bib7","doi-asserted-by":"crossref","DOI":"10.1007\/s40291-026-00833-w","article-title":"Neuromuscular junction as a molecular target in sarcopenia: mechanisms, therapeutic strategies, and future directions","author":"Qaisar","year":"2026","journal-title":"Mol Diagn Ther"},{"issue":"4","key":"10.1016\/j.pan.2026.07.001_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.jocd.2025.101618","article-title":"The interface of a leaky gut with neuromuscular junction degradation; implications for severe sarcopenia","volume":"28","author":"Qaisar","year":"2025","journal-title":"J Clin Densitom"},{"key":"10.1016\/j.pan.2026.07.001_bib9","doi-asserted-by":"crossref","DOI":"10.1002\/bcp.70065","article-title":"The improvement in muscle function following statin withdrawal might involve the repair of the neuromuscular junction","author":"Qaisar","year":"2025","journal-title":"Br J Clin Pharmacol"},{"issue":"5","key":"10.1016\/j.pan.2026.07.001_bib10","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1007\/s40291-024-00724-y","article-title":"Tracking the plasma C-Terminal agrin fragment as a biomarker of neuromuscular decline in 18- to 87-Year-Old men","volume":"28","author":"Qaisar","year":"2024","journal-title":"Mol Diagn Ther"},{"issue":"4","key":"10.1016\/j.pan.2026.07.001_bib11","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1007\/s12031-022-01970-7","article-title":"Evaluation of sarcopenia using biomarkers of the neuromuscular junction in Parkinson's disease","volume":"72","author":"Karim","year":"2022","journal-title":"J Mol Neurosci"},{"issue":"2","key":"10.1016\/j.pan.2026.07.001_bib12","doi-asserted-by":"crossref","DOI":"10.1093\/ageing\/afaf024","article-title":"Plasma brain-derived neurotrophic factor concentrations are elevated in community-dwelling adults with sarcopenia","volume":"54","author":"Pratt","year":"2025","journal-title":"Age Ageing"},{"issue":"15","key":"10.1016\/j.pan.2026.07.001_bib13","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25158283","article-title":"Role of interleukin 6 in acute pancreatitis: a possible marker for disease prognosis","volume":"25","author":"Mititelu","year":"2024","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.pan.2026.07.001_bib14","doi-asserted-by":"crossref","DOI":"10.1080\/07853890.2024.2384664","article-title":"Association of interleukin-6 with sarcopenia and its components in older adults: a systematic review and meta-analysis of cross-sectional studies","volume":"56","author":"Ding","year":"2024","journal-title":"Ann Med"},{"key":"10.1016\/j.pan.2026.07.001_bib15","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2024.1408312","article-title":"Unveiling the role of interleukin-6 in pancreatic cancer occurrence and progression","volume":"15","author":"Song","year":"2024","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.pan.2026.07.001_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biopen.2017.12.001","article-title":"Isoprostanes as markers for muscle aging in older athletes","volume":"6","author":"Vinel","year":"2018","journal-title":"Biochim Open"},{"issue":"8","key":"10.1016\/j.pan.2026.07.001_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e29734","article-title":"Associations of serum albumin and dietary protein intake with all-cause mortality in community-dwelling older adults at risk of sarcopenia","volume":"10","author":"Zhang","year":"2024","journal-title":"Heliyon"},{"issue":"1","key":"10.1016\/j.pan.2026.07.001_bib18","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1148\/radiol.2018181353","article-title":"Reporting standards for chronic pancreatitis by using CT, MRI, and MR cholangiopancreatography: the consortium for the study of chronic pancreatitis, diabetes, and pancreatic cancer","volume":"290","author":"Tirkes","year":"2019","journal-title":"Radiology"},{"issue":"8","key":"10.1016\/j.pan.2026.07.001_bib19","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.3748\/wjg.14.1218","article-title":"Diagnosis of mild chronic pancreatitis (Cambridge classification): comparative study using secretin injection-magnetic resonance cholangiopancreatography and endoscopic retrograde pancreatography","volume":"14","author":"Sai","year":"2008","journal-title":"World J Gastroenterol"},{"issue":"12","key":"10.1016\/j.pan.2026.07.001_bib20","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1007\/s10147-025-02890-3","article-title":"Plasma CAF22 and NfL reflect neuromuscular decline during cisplatin-based chemotherapy and radical cystectomy in muscle-invasive bladder cancer","volume":"30","author":"Qaisar","year":"2025","journal-title":"Int J Clin Oncol"},{"key":"10.1016\/j.pan.2026.07.001_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.rmed.2023.107510","article-title":"Butyrate supplementation reduces sarcopenia by repairing neuromuscular junction in patients with chronic obstructive pulmonary disease","volume":"222","author":"Qaisar","year":"2024","journal-title":"Respir Med"},{"issue":"5","key":"10.1016\/j.pan.2026.07.001_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.arcmed.2024.103025","article-title":"Resistance exercise reduces sarcopenia by repairing leaky gut in patients with Alzheimer's disease","volume":"55","author":"Qaisar","year":"2024","journal-title":"Arch Med Res"},{"issue":"20","key":"10.1016\/j.pan.2026.07.001_bib23","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1001\/jama.2013.281053","article-title":"World medical association declaration of helsinki: ethical principles for medical research involving human subjects","volume":"310","author":"World Medical","year":"2013","journal-title":"JAMA"},{"issue":"4","key":"10.1016\/j.pan.2026.07.001_bib24","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.resinv.2024.04.014","article-title":"Plasma levels of neurofilament light chain correlate with handgrip strength and sarcopenia in patients with chronic obstructive pulmonary disease","volume":"62","author":"Qaisar","year":"2024","journal-title":"Respir Investig"},{"issue":"2","key":"10.1016\/j.pan.2026.07.001_bib25","doi-asserted-by":"crossref","first-page":"641","DOI":"10.3233\/JAD-230201","article-title":"ACE inhibitors improve skeletal muscle by preserving neuromuscular junctions in patients with Alzheimer's disease","volume":"94","author":"Qaisar","year":"2023","journal-title":"J Alzheimers Dis"},{"issue":"23","key":"10.1016\/j.pan.2026.07.001_bib26","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph192316319","article-title":"Associations of the short physical performance battery (SPPB) with adverse health outcomes in older adults: a 14-Year Follow-Up from the English longitudinal study of ageing (ELSA)","volume":"19","author":"Western","year":"2022","journal-title":"Int J Environ Res Publ Health"},{"key":"10.1016\/j.pan.2026.07.001_bib27","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2022.934714","article-title":"The molecular effects of BDNF synthesis on skeletal muscle: a mini-review","volume":"13","author":"Renteria","year":"2022","journal-title":"Front Physiol"},{"issue":"9","key":"10.1016\/j.pan.2026.07.001_bib28","doi-asserted-by":"crossref","DOI":"10.3390\/jpm11090919","article-title":"Prediction of sarcopenia using multiple biomarkers of neuromuscular junction degeneration in chronic obstructive pulmonary disease","volume":"11","author":"Karim","year":"2021","journal-title":"J Personalized Med"},{"key":"10.1016\/j.pan.2026.07.001_bib29","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.3389\/fphys.2017.01045","article-title":"The role of inflammation in age-related sarcopenia","volume":"8","author":"Dalle","year":"2017","journal-title":"Front Physiol"},{"issue":"5","key":"10.1016\/j.pan.2026.07.001_bib30","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1097\/MOG.0000000000000195","article-title":"Inflammation in acute and chronic pancreatitis","volume":"31","author":"Habtezion","year":"2015","journal-title":"Curr Opin Gastroenterol"},{"key":"10.1016\/j.pan.2026.07.001_bib31","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.freeradbiomed.2024.11.046","article-title":"Reactive oxygen species in the pathogenesis of sarcopenia","volume":"227","author":"Xu","year":"2025","journal-title":"Free Radic Biol Med"},{"issue":"16","key":"10.1016\/j.pan.2026.07.001_bib32","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26167787","article-title":"A reassessment of sarcopenia from a redox perspective as a basis for preventive and therapeutic interventions","volume":"26","author":"Arcaro","year":"2025","journal-title":"Int J Mol Sci"},{"issue":"5","key":"10.1016\/j.pan.2026.07.001_bib33","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.4103\/NRR.NRR-D-24-01338","article-title":"Systematic review of mitochondrial dysfunction and oxidative stress in aging: a focus on neuromuscular junctions","volume":"21","author":"Chai","year":"2026","journal-title":"Neural Regen Res"},{"issue":"4","key":"10.1016\/j.pan.2026.07.001_bib34","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1002\/jcsm.13275","article-title":"Association between sarcopenia and frailty in elderly patients with chronic kidney disease","volume":"14","author":"Wang","year":"2023","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"1","key":"10.1016\/j.pan.2026.07.001_bib35","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1186\/s40001-025-02925-5","article-title":"Dynamic association of serum albumin changes with inflammation, nutritional status and clinical outcomes: a secondary analysis of a large prospective observational cohort study","volume":"30","author":"Li","year":"2025","journal-title":"Eur J Med Res"},{"issue":"7","key":"10.1016\/j.pan.2026.07.001_bib36","doi-asserted-by":"crossref","DOI":"10.3390\/nu17071237","article-title":"An overview of sarcopenia: focusing on nutritional treatment approaches","volume":"17","author":"Barone","year":"2025","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.pan.2026.07.001_bib37","doi-asserted-by":"crossref","first-page":"30","DOI":"10.14283\/jfa.2019.42","article-title":"Neuromuscular attributes are associated with poor mobility in older adults with vascular risk conditions","volume":"9","author":"Jor'dan","year":"2020","journal-title":"J Frailty Aging"},{"key":"10.1016\/j.pan.2026.07.001_bib38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13064-026-00241-0","article-title":"Sex hormones regulate neuromuscular junction structure, plasticity, and disease vulnerability","volume":"21","author":"Qaisar","year":"2026","journal-title":"Discov Neurosci"},{"issue":"1","key":"10.1016\/j.pan.2026.07.001_bib39","doi-asserted-by":"crossref","DOI":"10.1002\/rmb2.12569","article-title":"The roles of sex hormones in the pathophysiology of age-related sarcopenia and frailty","volume":"23","author":"Hosoi","year":"2024","journal-title":"Reprod Med Biol"}],"container-title":["Pancreatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1424390326002292?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1424390326002292?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T20:44:00Z","timestamp":1788468240000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1424390326002292"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":39,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S1424390326002292"],"URL":"https:\/\/doi.org\/10.1016\/j.pan.2026.07.001","relation":{},"ISSN":["1424-3903"],"issn-type":[{"value":"1424-3903","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neuromuscular biomarkers are associated with sarcopenia and physical performance in chronic pancreatitis: An integrative biomarker profiling study","name":"articletitle","label":"Article Title"},{"value":"Pancreatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pan.2026.07.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 IAP and EPC. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}